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HUP0303354A3 - 6-alpha, 9-alpha-difluoro-17-alpha-(2-furanylcarboxyl)oxy-11-betha-hydroxy-16-alpha-methyl-3-oxo-androst-1,4,-diene-17-carbothioic acid s-fluoromethyl ester with anti-inflammatory effect, process for its preparation and pahrmaceutical composition containing it - Google Patents

6-alpha, 9-alpha-difluoro-17-alpha-(2-furanylcarboxyl)oxy-11-betha-hydroxy-16-alpha-methyl-3-oxo-androst-1,4,-diene-17-carbothioic acid s-fluoromethyl ester with anti-inflammatory effect, process for its preparation and pahrmaceutical composition containing it

Info

Publication number
HUP0303354A3
HUP0303354A3 HU0303354A HUP0303354A HUP0303354A3 HU P0303354 A3 HUP0303354 A3 HU P0303354A3 HU 0303354 A HU0303354 A HU 0303354A HU P0303354 A HUP0303354 A HU P0303354A HU P0303354 A3 HUP0303354 A3 HU P0303354A3
Authority
HU
Hungary
Prior art keywords
alpha
furanylcarboxyl
pahrmaceutical
betha
androst
Prior art date
Application number
HU0303354A
Other languages
Hungarian (hu)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26244792&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0303354(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB0019172.6A external-priority patent/GB0019172D0/en
Priority claimed from GBGB0108800.4A external-priority patent/GB0108800D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of HUP0303354A2 publication Critical patent/HUP0303354A2/en
Publication of HUP0303354A3 publication Critical patent/HUP0303354A3/en
Publication of HU230328B1 publication Critical patent/HU230328B1/en
Priority to HUS1600012C priority Critical patent/HUS1600012I1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HU0303354A 2000-08-05 2001-08-03 6-alpha,9-alpha-difluoro-17-alpha-(2-furanylcarboxyl)oxy-11-beta-hydroxy-16-alpha-methyl-3-oxo-androst-1,4-diene-17-carbothioic acid s-fluoromethyl ester with anti-inflammatory effect HU230328B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HUS1600012C HUS1600012I1 (en) 2000-08-05 2016-03-11 6-alpha,9-alpha-difluoro-17-alpha-(2-furanylcarboxyl)oxy-11-beta-hydroxy-16-alpha-methyl-3-oxo-androst-1,4-diene-17-carbothioic acid s-fluoromethyl ester with anti-inflammatory effect

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0019172.6 2000-08-05
GBGB0019172.6A GB0019172D0 (en) 2000-08-05 2000-08-05 Novel compounds
GBGB0108800.4A GB0108800D0 (en) 2001-04-07 2001-04-07 Novel compounds
GB0108800.4 2001-04-07
PCT/GB2001/003495 WO2002012265A1 (en) 2000-08-05 2001-08-03 6.ALPHA., 9.ALPHA.-DIFLUORO-17.ALPHA.-`(2-FURANYLCARBOXYL) OXY!-11.BETA.-HYDROXY-16.ALPHA.-METHYL-3-OXO-ANDROST-1,4,-DIENE-17-CARBOTHIOIC ACID S-FLUOROMETHYL ESTER AS AN ANTI-INFLAMMATORY AGENT

Publications (3)

Publication Number Publication Date
HUP0303354A2 HUP0303354A2 (en) 2004-01-28
HUP0303354A3 true HUP0303354A3 (en) 2012-12-28
HU230328B1 HU230328B1 (en) 2016-02-29

Family

ID=26244792

Family Applications (3)

Application Number Title Priority Date Filing Date
HU0303084A HUP0303084A2 (en) 2000-08-05 2001-08-03 17 beta-carbothioate 17-alpha-arylcarbonyloxyloxy androstane derivative as anti-inflammatory agents, process for their preparation and pharmaceutical compositions containing them
HU0303354A HU230328B1 (en) 2000-08-05 2001-08-03 6-alpha,9-alpha-difluoro-17-alpha-(2-furanylcarboxyl)oxy-11-beta-hydroxy-16-alpha-methyl-3-oxo-androst-1,4-diene-17-carbothioic acid s-fluoromethyl ester with anti-inflammatory effect
HUS1600012C HUS1600012I1 (en) 2000-08-05 2016-03-11 6-alpha,9-alpha-difluoro-17-alpha-(2-furanylcarboxyl)oxy-11-beta-hydroxy-16-alpha-methyl-3-oxo-androst-1,4-diene-17-carbothioic acid s-fluoromethyl ester with anti-inflammatory effect

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HU0303084A HUP0303084A2 (en) 2000-08-05 2001-08-03 17 beta-carbothioate 17-alpha-arylcarbonyloxyloxy androstane derivative as anti-inflammatory agents, process for their preparation and pharmaceutical compositions containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
HUS1600012C HUS1600012I1 (en) 2000-08-05 2016-03-11 6-alpha,9-alpha-difluoro-17-alpha-(2-furanylcarboxyl)oxy-11-beta-hydroxy-16-alpha-methyl-3-oxo-androst-1,4-diene-17-carbothioic acid s-fluoromethyl ester with anti-inflammatory effect

Country Status (36)

Country Link
US (3) US7498321B2 (en)
EP (5) EP1305329B2 (en)
JP (3) JP4436041B2 (en)
KR (3) KR20030071751A (en)
CN (4) CN1315867C (en)
AP (1) AP1422A (en)
AR (3) AR032471A1 (en)
AT (2) ATE380194T1 (en)
AU (4) AU7649701A (en)
BG (1) BG66241B1 (en)
BR (2) BR0113039A (en)
CA (3) CA2634715A1 (en)
CO (2) CO5310550A1 (en)
CY (4) CY1107899T1 (en)
CZ (2) CZ304043B6 (en)
DE (3) DE122008000029I1 (en)
DK (3) DK1775305T3 (en)
DZ (1) DZ3468A1 (en)
EA (1) EA005992B1 (en)
ES (4) ES2523930T3 (en)
FR (1) FR08C0014I2 (en)
HK (1) HK1056181A1 (en)
HU (3) HUP0303084A2 (en)
IL (4) IL154148A0 (en)
LU (1) LU91429I2 (en)
MA (1) MA25899A1 (en)
MX (2) MXPA03001096A (en)
NL (1) NL300343I2 (en)
NO (4) NO324747B1 (en)
NZ (2) NZ523957A (en)
OA (1) OA12394A (en)
PL (2) PL359917A1 (en)
PT (3) PT1775305E (en)
SI (3) SI1775305T1 (en)
SK (1) SK287576B6 (en)
WO (2) WO2002012265A1 (en)

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