HUP0302614A3 - Il-8 receptor antagonists and pharmaceutical compositions containing them - Google Patents
Il-8 receptor antagonists and pharmaceutical compositions containing themInfo
- Publication number
- HUP0302614A3 HUP0302614A3 HU0302614A HUP0302614A HUP0302614A3 HU P0302614 A3 HUP0302614 A3 HU P0302614A3 HU 0302614 A HU0302614 A HU 0302614A HU P0302614 A HUP0302614 A HU P0302614A HU P0302614 A3 HUP0302614 A3 HU P0302614A3
- Authority
- HU
- Hungary
- Prior art keywords
- pharmaceutical compositions
- compositions containing
- receptor antagonists
- antagonists
- receptor
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/64—X and Y being nitrogen atoms, e.g. N-sulfonylguanidine
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/47—Y being a hetero atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
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- C07D207/14—Nitrogen atoms not forming part of a nitro radical
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- C—CHEMISTRY; METALLURGY
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- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
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- C07D295/26—Sulfur atoms
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19213200P | 2000-03-24 | 2000-03-24 | |
PCT/US2001/009216 WO2001072960A2 (en) | 2000-03-24 | 2001-03-23 | Il-8 receptor antagonists |
Publications (2)
Publication Number | Publication Date |
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HUP0302614A2 HUP0302614A2 (hu) | 2003-11-28 |
HUP0302614A3 true HUP0302614A3 (en) | 2005-05-30 |
Family
ID=22708394
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0302614A HUP0302614A3 (en) | 2000-03-24 | 2001-03-23 | Il-8 receptor antagonists and pharmaceutical compositions containing them |
Country Status (31)
Country | Link |
---|---|
US (1) | US6680317B2 (hu) |
EP (1) | EP1272175B1 (hu) |
JP (1) | JP2004508287A (hu) |
KR (1) | KR20040014901A (hu) |
CN (1) | CN1452483A (hu) |
AP (1) | AP1548A (hu) |
AR (1) | AR031101A1 (hu) |
AT (1) | ATE464893T1 (hu) |
AU (1) | AU2001249354A1 (hu) |
BG (1) | BG107035A (hu) |
BR (1) | BR0108867A (hu) |
CA (1) | CA2403787A1 (hu) |
CZ (1) | CZ20023192A3 (hu) |
DE (1) | DE60141896D1 (hu) |
DZ (1) | DZ3333A1 (hu) |
EA (1) | EA200201019A1 (hu) |
ES (1) | ES2344587T3 (hu) |
HK (1) | HK1053789A1 (hu) |
HU (1) | HUP0302614A3 (hu) |
IL (1) | IL151210A0 (hu) |
MA (1) | MA25739A1 (hu) |
MX (1) | MXPA02009355A (hu) |
MY (1) | MY128154A (hu) |
NO (1) | NO20024554D0 (hu) |
OA (1) | OA12235A (hu) |
PE (1) | PE20020839A1 (hu) |
PL (1) | PL205103B1 (hu) |
SK (1) | SK13682002A3 (hu) |
UY (1) | UY26627A1 (hu) |
WO (1) | WO2001072960A2 (hu) |
ZA (1) | ZA200207576B (hu) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CO5170528A1 (es) * | 1999-05-28 | 2002-06-27 | Smithkline Beecham Corp | Antagonistas de los receptores de la il-8 nistas del recpetor de la il-8 |
TW200418812A (en) * | 2002-10-29 | 2004-10-01 | Smithkline Beecham Corp | IL-8 receptor antagonists |
JP2007537272A (ja) | 2004-05-12 | 2007-12-20 | シェーリング コーポレイション | Cxcr1およびcxcr2ケモカインアンタゴニスト |
EP1812008A4 (en) * | 2004-10-20 | 2008-10-29 | Smithkline Beecham Corp | ANTAGONISTS OF THE IL-8 RECEPTOR |
US7893089B2 (en) * | 2006-04-21 | 2011-02-22 | GlaxoSmithKline, LLC | IL-8 receptor antagonists |
CN101495113A (zh) * | 2006-04-21 | 2009-07-29 | 史密丝克莱恩比彻姆公司 | Il-8受体拮抗剂 |
PE20080943A1 (es) * | 2006-06-23 | 2008-09-27 | Smithkline Beecham Corp | Sal toluenosulfonato de 4-{[6-cloro-3-({[(2-cloro-3-fluorofenil)amino]carbonil}amino)-2-hidroxifenil]sulfonil}-1-piperazinacarboxilato de 1,1-dimetiletilo como antagonista del receptor de il-8 |
US20090131329A1 (en) * | 2007-09-14 | 2009-05-21 | Edmund John Miller | Treatment for allograft rejection |
RU2593759C2 (ru) * | 2010-09-03 | 2016-08-10 | ФОРМА ТиЭм, ЭлЭлСИ | Гуанидиновые соединения и композиции для ингибирования nampt |
US8648070B2 (en) | 2010-12-17 | 2014-02-11 | Boehringer Ingelheim International Gmbh | Bicyclic ring system substituted sulfonamide functionalised phenols as medicaments |
BR112014027700A2 (pt) * | 2012-05-08 | 2017-06-27 | Ishihara Sangyo Kaisha | método para produção de um composto de ácido benzoico substituído |
US12227501B2 (en) | 2019-02-07 | 2025-02-18 | Bayer Aktiengesellschaft | 3-amino-2-[2-(acylamino)pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as CSNK1 inhibitors |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0809492A4 (en) * | 1995-02-17 | 2007-01-24 | Smithkline Beecham Corp | IL-8 RECEPTOR ANTAGONISTS |
AR008290A1 (es) | 1996-08-15 | 1999-12-29 | Smithkline Beecham Corp | Nuevos compuestos que contienen guanidina utiles como antagonistas de los receptores de il-8, composiciones farmaceuticas que los contienenprocedimiento para la preparacion de dichos compuestos y procedimiento para la preparacion de intermediarios. |
EP1115701B1 (en) * | 1998-09-23 | 2003-05-21 | Tularik Inc. | Arylsulfonanilide ureas |
UY25842A1 (es) * | 1998-12-16 | 2001-04-30 | Smithkline Beecham Corp | Antagonistas de receptores de il-8 |
-
2001
- 2001-03-21 UY UY26627A patent/UY26627A1/es not_active Application Discontinuation
- 2001-03-22 MY MYPI20011375A patent/MY128154A/en unknown
- 2001-03-22 AR ARP010101346A patent/AR031101A1/es not_active Application Discontinuation
- 2001-03-23 AP APAP/P/2002/002599A patent/AP1548A/en active
- 2001-03-23 MX MXPA02009355A patent/MXPA02009355A/es active IP Right Grant
- 2001-03-23 HU HU0302614A patent/HUP0302614A3/hu unknown
- 2001-03-23 SK SK1368-2002A patent/SK13682002A3/sk not_active Application Discontinuation
- 2001-03-23 EA EA200201019A patent/EA200201019A1/ru unknown
- 2001-03-23 DE DE60141896T patent/DE60141896D1/de not_active Expired - Lifetime
- 2001-03-23 JP JP2001571875A patent/JP2004508287A/ja not_active Withdrawn
- 2001-03-23 US US10/221,908 patent/US6680317B2/en not_active Expired - Fee Related
- 2001-03-23 ES ES01922568T patent/ES2344587T3/es not_active Expired - Lifetime
- 2001-03-23 PE PE2001000277A patent/PE20020839A1/es not_active Application Discontinuation
- 2001-03-23 KR KR1020027012514A patent/KR20040014901A/ko active IP Right Grant
- 2001-03-23 AT AT01922568T patent/ATE464893T1/de not_active IP Right Cessation
- 2001-03-23 WO PCT/US2001/009216 patent/WO2001072960A2/en active Application Filing
- 2001-03-23 IL IL15121001A patent/IL151210A0/xx unknown
- 2001-03-23 DZ DZ013333A patent/DZ3333A1/fr active
- 2001-03-23 CA CA002403787A patent/CA2403787A1/en not_active Abandoned
- 2001-03-23 CZ CZ20023192A patent/CZ20023192A3/cs unknown
- 2001-03-23 PL PL366315A patent/PL205103B1/pl not_active IP Right Cessation
- 2001-03-23 OA OA1200200297A patent/OA12235A/en unknown
- 2001-03-23 CN CN01806920A patent/CN1452483A/zh active Pending
- 2001-03-23 AU AU2001249354A patent/AU2001249354A1/en not_active Abandoned
- 2001-03-23 BR BR0108867-0A patent/BR0108867A/pt not_active IP Right Cessation
- 2001-03-23 EP EP01922568A patent/EP1272175B1/en not_active Expired - Lifetime
-
2002
- 2002-08-26 BG BG107035A patent/BG107035A/bg unknown
- 2002-09-20 ZA ZA200207576A patent/ZA200207576B/en unknown
- 2002-09-20 MA MA26831A patent/MA25739A1/fr unknown
- 2002-09-23 NO NO20024554A patent/NO20024554D0/no not_active Application Discontinuation
-
2003
- 2003-06-23 HK HK03104498.6A patent/HK1053789A1/zh unknown
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