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HUP0105230A2 - Specifikus hibrid promóterek alkalmazása szöveti kifejeződés szabályozására - Google Patents

Specifikus hibrid promóterek alkalmazása szöveti kifejeződés szabályozására

Info

Publication number
HUP0105230A2
HUP0105230A2 HU0105230A HUP0105230A HUP0105230A2 HU P0105230 A2 HUP0105230 A2 HU P0105230A2 HU 0105230 A HU0105230 A HU 0105230A HU P0105230 A HUP0105230 A HU P0105230A HU P0105230 A2 HUP0105230 A2 HU P0105230A2
Authority
HU
Hungary
Prior art keywords
hybrid promoters
tissue expression
specific hybrid
promoter
controlling tissue
Prior art date
Application number
HU0105230A
Other languages
English (en)
Inventor
Didier Branellec
Raphaël Darteil
Abderrahim Mahfoudi
Daniel Scherman
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9812000A external-priority patent/FR2783839B1/fr
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of HUP0105230A2 publication Critical patent/HUP0105230A2/hu
Publication of HUP0105230A3 publication Critical patent/HUP0105230A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4716—Muscle proteins, e.g. myosin, actin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10345—Special targeting system for viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A tal lm ny t rgy t egy olyan hibrid promóter képezi, amely mag bafoglalja - egy erős és ubikvista promóter/enhanszer enhanszer régiójnak egy részét vagy egészét, és - egy simaizom sejtekben specifikusexpressziót lehetővé tévő promóter régiót, valamint a tal lm ny t rgyae promótert tartalmazó b rmely vektor vagy sejt és azok alkalmaz sa. Ó
HU0105230A 1998-09-25 1999-09-23 Use of specific hybrid promoters for controlling tissue expression HUP0105230A3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9812000A FR2783839B1 (fr) 1998-09-25 1998-09-25 Utilisation de promoteurs specifiques hybrides pour controler l'expression tissulaire
US12329899P 1999-03-04 1999-03-04
PCT/FR1999/002265 WO2000018908A1 (fr) 1998-09-25 1999-09-23 Utilisation de promoteurs specifiques hybrides pour controler l'expression tissulaire

Publications (2)

Publication Number Publication Date
HUP0105230A2 true HUP0105230A2 (hu) 2002-04-29
HUP0105230A3 HUP0105230A3 (en) 2003-10-28

Family

ID=26234566

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0105230A HUP0105230A3 (en) 1998-09-25 1999-09-23 Use of specific hybrid promoters for controlling tissue expression

Country Status (9)

Country Link
EP (1) EP1115857A1 (hu)
JP (1) JP2002525109A (hu)
KR (1) KR20010075338A (hu)
CN (1) CN1326506A (hu)
AU (1) AU775717B2 (hu)
CA (1) CA2343922A1 (hu)
HU (1) HUP0105230A3 (hu)
IL (1) IL142107A0 (hu)
WO (1) WO2000018908A1 (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7482155B1 (en) 2000-07-05 2009-01-27 Transgene S.A. Chimeric promoters for controlling expression in smooth muscle cells
EP1310561A1 (en) * 2001-11-09 2003-05-14 Transgene S.A. Chimeric promoters for controlling expression in skeletal muscle cells

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5266490A (en) * 1991-03-28 1993-11-30 Regeneron Pharmaceuticals, Inc. Mammalian expression vector
US5298422A (en) * 1991-11-06 1994-03-29 Baylor College Of Medicine Myogenic vector systems
DK0787200T3 (da) * 1994-10-28 2005-08-15 Univ Pennsylvania Forbedret adenovirus og fremgangsmåder til anvendelse heraf
JP4131569B2 (ja) * 1996-12-02 2008-08-13 バレンティス・インコーポレーテッド インシュリン様成長因子ｉ（ｉｇｆ−ｉ）発現系及び使用法

Also Published As

Publication number Publication date
CN1326506A (zh) 2001-12-12
AU775717B2 (en) 2004-08-12
KR20010075338A (ko) 2001-08-09
CA2343922A1 (fr) 2000-04-06
EP1115857A1 (fr) 2001-07-18
HUP0105230A3 (en) 2003-10-28
JP2002525109A (ja) 2002-08-13
WO2000018908A1 (fr) 2000-04-06
IL142107A0 (en) 2002-03-10
AU5632499A (en) 2000-04-17

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees