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HUP0103826A2 - Eljárás zofenopril kalciumsó előállítására és a vegyületet tartalmazó gyógyszerkészítmény és alkalmazása - Google Patents

Eljárás zofenopril kalciumsó előállítására és a vegyületet tartalmazó gyógyszerkészítmény és alkalmazása

Info

Publication number
HUP0103826A2
HUP0103826A2 HU0103826A HUP0103826A HUP0103826A2 HU P0103826 A2 HUP0103826 A2 HU P0103826A2 HU 0103826 A HU0103826 A HU 0103826A HU P0103826 A HUP0103826 A HU P0103826A HU P0103826 A2 HUP0103826 A2 HU P0103826A2
Authority
HU
Hungary
Prior art keywords
preparation
calcium salt
medicament containing
zofenopril calcium
zofenopril
Prior art date
Application number
HU0103826A
Other languages
English (en)
Inventor
Anita Falezza
Antonio Giachetti
Raffaello Giorgi
Carlo Mannucci
Original Assignee
Menarini Ricerche S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Ricerche S.P.A. filed Critical Menarini Ricerche S.P.A.
Publication of HUP0103826A2 publication Critical patent/HUP0103826A2/hu
Publication of HUP0103826A3 publication Critical patent/HUP0103826A3/hu
Publication of HU227557B1 publication Critical patent/HU227557B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
    • C01F11/00—Compounds of calcium, strontium, or barium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Geology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU0103826A 1998-08-04 1999-07-30 A process for the preparation of zofenopril calcium salt and medicament containing it and its use HU227557B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI001833A IT1301993B1 (it) 1998-08-04 1998-08-04 Processo per la preparazione di zofenopril sale di calcio.
PCT/EP1999/005461 WO2000007984A1 (en) 1998-08-04 1999-07-30 A process for the preparation of zofenopril calcium salt

Publications (3)

Publication Number Publication Date
HUP0103826A2 true HUP0103826A2 (hu) 2002-02-28
HUP0103826A3 HUP0103826A3 (en) 2002-03-28
HU227557B1 HU227557B1 (en) 2011-08-29

Family

ID=11380611

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0103826A HU227557B1 (en) 1998-08-04 1999-07-30 A process for the preparation of zofenopril calcium salt and medicament containing it and its use

Country Status (32)

Country Link
US (2) US6521760B1 (hu)
EP (1) EP1102745B1 (hu)
JP (1) JP2002522417A (hu)
KR (1) KR100593428B1 (hu)
CN (1) CN1146538C (hu)
AT (1) ATE266635T1 (hu)
AU (1) AU5372299A (hu)
BG (1) BG65022B1 (hu)
BR (1) BR9912842A (hu)
CA (1) CA2339283C (hu)
CU (1) CU23171A3 (hu)
CZ (1) CZ301908B6 (hu)
DE (1) DE69917282T2 (hu)
DK (1) DK1102745T3 (hu)
EA (1) EA003454B1 (hu)
EE (1) EE04798B1 (hu)
ES (1) ES2221417T3 (hu)
HK (1) HK1039616B (hu)
HR (1) HRP20010083B1 (hu)
HU (1) HU227557B1 (hu)
IL (1) IL141222A0 (hu)
IT (1) IT1301993B1 (hu)
NO (1) NO319773B1 (hu)
PL (1) PL193828B1 (hu)
PT (1) PT1102745E (hu)
RS (1) RS49768B (hu)
SI (1) SI1102745T1 (hu)
SK (1) SK285527B6 (hu)
TR (1) TR200100272T2 (hu)
UA (1) UA65628C2 (hu)
WO (1) WO2000007984A1 (hu)
ZA (1) ZA200100907B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007003963A1 (en) 2005-07-01 2007-01-11 Generics [Uk] Limited Zofenopril calcium in polymorph form c
EA012845B1 (ru) * 2005-12-09 2009-12-30 Менарини Интернэшнл Оперейшнс Люксембург С. А. Фармацевтическая композиция, содержащая зофеноприл и hctz, для лечения гипертензии
DK2041083T3 (en) * 2006-05-26 2015-01-26 Generics Uk Ltd Methods for the preparation of zofenopril calcium
GB0715626D0 (en) * 2007-08-10 2007-09-19 Generics Uk Ltd Crystalline form of zofenopril calcium
US8853421B2 (en) 2008-02-27 2014-10-07 Generics [Uk] Limited Crystalline forms of zofenopril calcium
CA2715726C (en) * 2008-02-27 2014-12-02 Vinayak Gore Novel crystalline forms
EP2389360A4 (en) * 2009-01-23 2013-01-16 Glenmark Generics Ltd METHOD FOR PRODUCING ZOFENOPRIL AND PHARMACEUTICAL ACCEPTIC SALTS THEREFOR
SI23949A (sl) 2011-12-19 2013-06-28 Silverstone Pharma Nove kristalne soli zofenoprila, postopek za njihovo dobivanje in njihova uporaba v terapiji
CN104138359B (zh) * 2013-05-06 2016-03-02 扬子江药业集团上海海尼药业有限公司 佐芬普利钙片的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4105776A (en) * 1976-06-21 1978-08-08 E. R. Squibb & Sons, Inc. Proline derivatives and related compounds
US4154935A (en) * 1978-02-21 1979-05-15 E. R. Squibb & Sons, Inc. Halogen substituted mercaptoacylamino acids
US4316906A (en) * 1978-08-11 1982-02-23 E. R. Squibb & Sons, Inc. Mercaptoacyl derivatives of substituted prolines

Also Published As

Publication number Publication date
SI1102745T1 (en) 2004-10-31
EE04798B1 (et) 2007-04-16
HRP20010083A2 (en) 2002-02-28
DE69917282D1 (de) 2004-06-17
HUP0103826A3 (en) 2002-03-28
PT1102745E (pt) 2004-08-31
US6521760B1 (en) 2003-02-18
CZ2001408A3 (cs) 2001-07-11
EP1102745B1 (en) 2004-05-12
EE200100065A (et) 2002-06-17
HU227557B1 (en) 2011-08-29
EP1102745A1 (en) 2001-05-30
DK1102745T3 (da) 2004-08-02
IT1301993B1 (it) 2000-07-20
NO319773B1 (no) 2005-09-12
JP2002522417A (ja) 2002-07-23
IL141222A0 (en) 2002-03-10
YU7501A (sh) 2005-06-10
WO2000007984A1 (en) 2000-02-17
BR9912842A (pt) 2001-10-16
UA65628C2 (uk) 2004-04-15
KR100593428B1 (ko) 2006-06-28
ITMI981833A1 (it) 2000-02-04
HK1039616A1 (en) 2002-05-03
EA003454B1 (ru) 2003-06-26
CA2339283C (en) 2009-03-17
ITMI981833A0 (it) 1998-08-04
CN1146538C (zh) 2004-04-21
NO20010552D0 (no) 2001-02-01
RS49768B (sr) 2008-06-05
CU23171A3 (es) 2006-09-22
HK1039616B (zh) 2004-10-08
PL345814A1 (en) 2002-01-14
KR20010072171A (ko) 2001-07-31
AU5372299A (en) 2000-02-28
EA200100095A1 (ru) 2001-08-27
US6515012B2 (en) 2003-02-04
PL193828B1 (pl) 2007-03-30
TR200100272T2 (tr) 2001-05-21
ES2221417T3 (es) 2004-12-16
BG65022B1 (bg) 2006-12-29
HRP20010083B1 (en) 2005-02-28
BG105176A (en) 2001-11-30
DE69917282T2 (de) 2005-05-25
CN1316992A (zh) 2001-10-10
US20020156293A1 (en) 2002-10-24
SK1632001A3 (en) 2001-09-11
CZ301908B6 (cs) 2010-07-28
CA2339283A1 (en) 2000-02-17
NO20010552L (no) 2001-02-01
SK285527B6 (sk) 2007-03-01
ZA200100907B (en) 2001-10-04
ATE266635T1 (de) 2004-05-15

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