HUP0103826A2 - A process for the preparation of zofenopril calcium salt and medicament containing it and its use - Google Patents

A process for the preparation of zofenopril calcium salt and medicament containing it and its use

Info

Publication number: HUP0103826A2
Authority: HU; Hungary
Prior art keywords: preparation; calcium salt; medicament containing; zofenopril calcium; zofenopril
Prior art date: 1998-08-04

Application number

HU0103826A

Other languages

Hungarian (hu)

Inventor

Anita Falezza

Antonio Giachetti

Raffaello Giorgi

Carlo Mannucci

Original Assignee

Menarini Ricerche S.P.A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-08-04

Filing date

1999-07-30

Publication date

2002-02-28

1999-07-30 Application filed by Menarini Ricerche S.P.A. filed Critical Menarini Ricerche S.P.A.

2002-02-28 Publication of HUP0103826A2 publication Critical patent/HUP0103826A2/en

2002-03-28 Publication of HUP0103826A3 publication Critical patent/HUP0103826A3/en

2011-08-29 Publication of HU227557B1 publication Critical patent/HU227557B1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01F—COMPOUNDS OF THE METALS BERYLLIUM, MAGNESIUM, ALUMINIUM, CALCIUM, STRONTIUM, BARIUM, RADIUM, THORIUM, OR OF THE RARE-EARTH METALS
- C01F11/00—Compounds of calcium, strontium, or barium
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Cardiology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Geology (AREA)
Inorganic Chemistry (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

HU0103826A 1998-08-04 1999-07-30 A process for the preparation of zofenopril calcium salt and medicament containing it and its use HU227557B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT1998MI001833A IT1301993B1 (en)	1998-08-04	1998-08-04	PROCESS FOR THE PREPARATION OF ZOFENOPRIL CALCIUM SALT.
PCT/EP1999/005461 WO2000007984A1 (en)	1998-08-04	1999-07-30	A process for the preparation of zofenopril calcium salt

Publications (3)

Publication Number	Publication Date
HUP0103826A2 true HUP0103826A2 (en)	2002-02-28
HUP0103826A3 HUP0103826A3 (en)	2002-03-28
HU227557B1 HU227557B1 (en)	2011-08-29

Family

ID=11380611

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU0103826A HU227557B1 (en)	1998-08-04	1999-07-30	A process for the preparation of zofenopril calcium salt and medicament containing it and its use

Country Status (32)

Country	Link
US (2)	US6521760B1 (en)
EP (1)	EP1102745B1 (en)
JP (1)	JP2002522417A (en)
KR (1)	KR100593428B1 (en)
CN (1)	CN1146538C (en)
AT (1)	ATE266635T1 (en)
AU (1)	AU5372299A (en)
BG (1)	BG65022B1 (en)
BR (1)	BR9912842A (en)
CA (1)	CA2339283C (en)
CU (1)	CU23171A3 (en)
CZ (1)	CZ301908B6 (en)
DE (1)	DE69917282T2 (en)
DK (1)	DK1102745T3 (en)
EA (1)	EA003454B1 (en)
EE (1)	EE04798B1 (en)
ES (1)	ES2221417T3 (en)
HK (1)	HK1039616B (en)
HR (1)	HRP20010083B1 (en)
HU (1)	HU227557B1 (en)
IL (1)	IL141222A0 (en)
IT (1)	IT1301993B1 (en)
NO (1)	NO319773B1 (en)
PL (1)	PL193828B1 (en)
PT (1)	PT1102745E (en)
RS (1)	RS49768B (en)
SI (1)	SI1102745T1 (en)
SK (1)	SK285527B6 (en)
TR (1)	TR200100272T2 (en)
UA (1)	UA65628C2 (en)
WO (1)	WO2000007984A1 (en)
ZA (1)	ZA200100907B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1899297B1 (en) *	2005-07-01	2015-12-09	Generics [UK] Limited	Zofenopril calcium in polymorph form c
EA012845B1 (en) *	2005-12-09	2009-12-30	Менарини Интернэшнл Оперейшнс Люксембург С. А.	Pharmaceutical compositions comprising zofenopril and hctz for treating hypertension
EP2041083B1 (en) *	2006-05-26	2014-11-05	Generics [UK] Limited	Methods of preparing zofenopril calcium
GB0715626D0 (en) *	2007-08-10	2007-09-19	Generics Uk Ltd	Crystalline form of zofenopril calcium
CN101981004B (en) *	2008-02-27	2014-09-17	基因里克斯(英国)有限公司	Novel crystalline forms
US8853421B2 (en)	2008-02-27	2014-10-07	Generics [Uk] Limited	Crystalline forms of zofenopril calcium
EP2389360A4 (en) *	2009-01-23	2013-01-16	Glenmark Generics Ltd	A process for the preparation of zofenopril and its pharmaceutically acceptable salts thereof
SI23949A (en)	2011-12-19	2013-06-28	Silverstone Pharma	The new crystalline salts of zofenopril, the procedure for obtaining them and their use in therapy
CN104138359B (en) *	2013-05-06	2016-03-02	扬子江药业集团上海海尼药业有限公司	The preparation method of zofenopril calcium tablet

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4105776A (en) *	1976-06-21	1978-08-08	E. R. Squibb & Sons, Inc.	Proline derivatives and related compounds
US4154935A (en) *	1978-02-21	1979-05-15	E. R. Squibb & Sons, Inc.	Halogen substituted mercaptoacylamino acids
US4316906A (en)	1978-08-11	1982-02-23	E. R. Squibb & Sons, Inc.	Mercaptoacyl derivatives of substituted prolines

1998
- 1998-08-04 IT IT1998MI001833A patent/IT1301993B1/en active IP Right Grant
1999
- 1999-07-30 DE DE69917282T patent/DE69917282T2/en not_active Expired - Lifetime
- 1999-07-30 BR BR9912842-0A patent/BR9912842A/en not_active Application Discontinuation
- 1999-07-30 EA EA200100095A patent/EA003454B1/en not_active IP Right Cessation
- 1999-07-30 JP JP2000563619A patent/JP2002522417A/en active Pending
- 1999-07-30 AT AT99939416T patent/ATE266635T1/en active
- 1999-07-30 PT PT99939416T patent/PT1102745E/en unknown
- 1999-07-30 US US09/762,054 patent/US6521760B1/en not_active Expired - Fee Related
- 1999-07-30 IL IL14122299A patent/IL141222A0/en not_active IP Right Cessation
- 1999-07-30 SK SK163-2001A patent/SK285527B6/en not_active IP Right Cessation
- 1999-07-30 AU AU53722/99A patent/AU5372299A/en not_active Abandoned
- 1999-07-30 UA UA2001010590A patent/UA65628C2/en unknown
- 1999-07-30 KR KR1020017001379A patent/KR100593428B1/en not_active IP Right Cessation
- 1999-07-30 PL PL99345814A patent/PL193828B1/en unknown
- 1999-07-30 CN CNB998105171A patent/CN1146538C/en not_active Expired - Lifetime
- 1999-07-30 EP EP99939416A patent/EP1102745B1/en not_active Expired - Lifetime
- 1999-07-30 RS YUP-75/01A patent/RS49768B/en unknown
- 1999-07-30 CA CA002339283A patent/CA2339283C/en not_active Expired - Lifetime
- 1999-07-30 DK DK99939416T patent/DK1102745T3/en active
- 1999-07-30 TR TR2001/00272T patent/TR200100272T2/en unknown
- 1999-07-30 ES ES99939416T patent/ES2221417T3/en not_active Expired - Lifetime
- 1999-07-30 EE EEP200100065A patent/EE04798B1/en unknown
- 1999-07-30 HU HU0103826A patent/HU227557B1/en unknown
- 1999-07-30 CZ CZ20010408A patent/CZ301908B6/en not_active IP Right Cessation
- 1999-07-30 WO PCT/EP1999/005461 patent/WO2000007984A1/en active IP Right Grant
- 1999-07-30 SI SI9930575T patent/SI1102745T1/en unknown
2001
- 2001-01-24 BG BG105176A patent/BG65022B1/en unknown
- 2001-02-01 ZA ZA200100907A patent/ZA200100907B/en unknown
- 2001-02-01 HR HR20010083A patent/HRP20010083B1/en not_active IP Right Cessation
- 2001-02-01 NO NO20010552A patent/NO319773B1/en not_active IP Right Cessation
- 2001-02-01 CU CU20010032A patent/CU23171A3/en unknown
2002
- 2002-02-21 HK HK02101248.6A patent/HK1039616B/en not_active IP Right Cessation
- 2002-05-28 US US10/155,129 patent/US6515012B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
UA65628C2 (en)	2004-04-15
CN1146538C (en)	2004-04-21
YU7501A (en)	2005-06-10
HUP0103826A3 (en)	2002-03-28
HK1039616A1 (en)	2002-05-03
SI1102745T1 (en)	2004-10-31
US6521760B1 (en)	2003-02-18
EP1102745B1 (en)	2004-05-12
JP2002522417A (en)	2002-07-23
PT1102745E (en)	2004-08-31
ZA200100907B (en)	2001-10-04
HRP20010083A2 (en)	2002-02-28
CA2339283A1 (en)	2000-02-17
DK1102745T3 (en)	2004-08-02
ATE266635T1 (en)	2004-05-15
KR20010072171A (en)	2001-07-31
IT1301993B1 (en)	2000-07-20
NO319773B1 (en)	2005-09-12
ITMI981833A0 (en)	1998-08-04
ES2221417T3 (en)	2004-12-16
CA2339283C (en)	2009-03-17
PL345814A1 (en)	2002-01-14
PL193828B1 (en)	2007-03-30
WO2000007984A1 (en)	2000-02-17
CZ301908B6 (en)	2010-07-28
EA200100095A1 (en)	2001-08-27
AU5372299A (en)	2000-02-28
HK1039616B (en)	2004-10-08
EA003454B1 (en)	2003-06-26
TR200100272T2 (en)	2001-05-21
BG105176A (en)	2001-11-30
IL141222A0 (en)	2002-03-10
DE69917282T2 (en)	2005-05-25
US6515012B2 (en)	2003-02-04
NO20010552D0 (en)	2001-02-01
BG65022B1 (en)	2006-12-29
DE69917282D1 (en)	2004-06-17
EE200100065A (en)	2002-06-17
SK1632001A3 (en)	2001-09-11
HU227557B1 (en)	2011-08-29
BR9912842A (en)	2001-10-16
CU23171A3 (en)	2006-09-22
HRP20010083B1 (en)	2005-02-28
CZ2001408A3 (en)	2001-07-11
ITMI981833A1 (en)	2000-02-04
EP1102745A1 (en)	2001-05-30
US20020156293A1 (en)	2002-10-24
KR100593428B1 (en)	2006-06-28
NO20010552L (en)	2001-02-01
CN1316992A (en)	2001-10-10
EE04798B1 (en)	2007-04-16
SK285527B6 (en)	2007-03-01
RS49768B (en)	2008-06-05

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