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HUP0002176A2 - Vakcinákban vagy diagnosztikai vizsgálatokban alkalmazható PRRSV-peptidszekvenciákat azonosító PRRSV-antigénhelyek - Google Patents

Vakcinákban vagy diagnosztikai vizsgálatokban alkalmazható PRRSV-peptidszekvenciákat azonosító PRRSV-antigénhelyek

Info

Publication number
HUP0002176A2
HUP0002176A2 HU0002176A HUP0002176A HUP0002176A2 HU P0002176 A2 HUP0002176 A2 HU P0002176A2 HU 0002176 A HU0002176 A HU 0002176A HU P0002176 A HUP0002176 A HU P0002176A HU P0002176 A2 HUP0002176 A2 HU P0002176A2
Authority
HU
Hungary
Prior art keywords
vaccines
peptides
antibodies
peptide sequences
diagnostic assays
Prior art date
Application number
HU0002176A
Other languages
English (en)
Inventor
Jan Langeveld
Janneke Meulenberg
Antonie Paul Van Nieuwstadt
Original Assignee
Stichting Dienst Landbouwkundig Onderzoek
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stichting Dienst Landbouwkundig Onderzoek filed Critical Stichting Dienst Landbouwkundig Onderzoek
Publication of HUP0002176A2 publication Critical patent/HUP0002176A2/hu
Publication of HUP0002176A3 publication Critical patent/HUP0002176A3/hu
Publication of HU228704B1 publication Critical patent/HU228704B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

A találmány tárgyát a PRRSV GP4-protein neutralizációs helyénekmegfelelő aminosavszekvenciából származó aminosavszekvenciáttartalmazó, neutralizáló ellenanyagok termelődését kiváltó peptidekképezik, amelyek lehetnek legalább két különböző PRRSV-izolátummalreagáló ellenanyagok termelődését kiváltó peptidek, vagy legalább kétkülönböző PRRSV-izolátum megkülönböztetésére alkalmas ellenanyagoktermelődését kiváltó peptidek. A találmány tárgyát képezik továbbá aGP4-protein neutralizációs helyének megfelelő neutralizálóellenanyagokat indukáló immunológiai készítmények, vakcinák PRRS-fertőzés megelőzésére, a peptidekkel reagáló szintetikus ellenanyagok,továbbá diagnosztikai reagenskészletek, valamint alkalmazásaik. Atalálmány szerinti megoldás PRRS-vírusok vizsgálata területénalkalmazható. Ó
HU0002176A 1997-05-06 1998-05-05 Prrsv antigenic sites identifying peptide sequences of prrs virus for use in vaccines or diagnostic assays HU228704B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97201343 1997-05-06
PCT/NL1998/000251 WO1998050426A1 (en) 1997-05-06 1998-05-05 Prrsv antigenic sites identifying peptide sequences of prrs virus for use in vaccines or diagnostic assays

Publications (3)

Publication Number Publication Date
HUP0002176A2 true HUP0002176A2 (hu) 2000-11-28
HUP0002176A3 HUP0002176A3 (en) 2001-09-28
HU228704B1 HU228704B1 (en) 2013-05-28

Family

ID=8228298

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0002176A HU228704B1 (en) 1997-05-06 1998-05-05 Prrsv antigenic sites identifying peptide sequences of prrs virus for use in vaccines or diagnostic assays

Country Status (21)

Country Link
US (1) US6495138B1 (hu)
EP (2) EP0980387B1 (hu)
JP (1) JP2000512313A (hu)
KR (1) KR100388257B1 (hu)
CN (1) CN1259141B (hu)
AT (1) ATE365746T1 (hu)
AU (1) AU754938B2 (hu)
BR (1) BR9809221A (hu)
CA (2) CA2703181C (hu)
CZ (1) CZ297371B6 (hu)
DE (1) DE69837992T2 (hu)
DK (1) DK0980387T3 (hu)
ES (1) ES2289781T3 (hu)
HU (1) HU228704B1 (hu)
ID (1) ID23399A (hu)
PL (1) PL197057B1 (hu)
PT (1) PT980387E (hu)
RU (1) RU2220978C2 (hu)
SK (1) SK286063B6 (hu)
UA (1) UA73915C2 (hu)
WO (1) WO1998050426A1 (hu)

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AR078253A1 (es) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
EP2576789A4 (en) * 2010-06-02 2014-01-22 Virginia Tech Intell Prop NEW MODIFIED LIVESTINE VACCINES (MLV) AND SUB-VEIN VACCINES OBTAINED BY DNA SHUFFLING AGAINST PRRS VIRUS
CN101885759B (zh) * 2010-06-25 2013-01-09 国家兽用生物制品工程技术研究中心 一种特异性结合猪繁殖与呼吸综合症病毒的多肽及其筛选方法和应用
BR112013020966B1 (pt) 2011-02-17 2020-05-26 Boehringer Ingelheim Vetmedica Gmbh Processo em escala comercial para produção do prrsv
PH12017500962B1 (en) 2011-02-17 2023-02-22 Boehringer Ingelheim Vetmedica Gmbh Novel european prrsv strain
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
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CN103421817B (zh) * 2012-10-15 2016-01-13 华中农业大学 人工合成的猪繁殖与呼吸综合征病毒多表位基因及应用
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CN112458115B (zh) * 2020-10-21 2022-06-07 天津农学院 一种基因构建重组质粒pEGFP-GRE-GP5gB及应用

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Also Published As

Publication number Publication date
CA2289980C (en) 2010-07-20
CA2703181A1 (en) 1998-11-12
HU228704B1 (en) 2013-05-28
DE69837992D1 (de) 2007-08-09
ES2289781T3 (es) 2008-02-01
KR100388257B1 (ko) 2003-06-19
CN1259141A (zh) 2000-07-05
PL197057B1 (pl) 2008-02-29
DK0980387T3 (da) 2007-10-22
ATE365746T1 (de) 2007-07-15
AU7457198A (en) 1998-11-27
ID23399A (id) 2000-04-20
BR9809221A (pt) 2000-07-04
CZ9903932A3 (cs) 2000-10-11
EP0980387A1 (en) 2000-02-23
SK286063B6 (sk) 2008-02-05
US6495138B1 (en) 2002-12-17
JP2000512313A (ja) 2000-09-19
HUP0002176A3 (en) 2001-09-28
SK152699A3 (en) 2000-08-14
AU754938B2 (en) 2002-11-28
CA2289980A1 (en) 1998-11-12
RU2220978C2 (ru) 2004-01-10
EP1882696A3 (en) 2008-03-05
UA73915C2 (uk) 2005-10-17
PT980387E (pt) 2007-07-31
WO1998050426A1 (en) 1998-11-12
EP1882696A2 (en) 2008-01-30
CA2703181C (en) 2016-06-28
EP0980387B1 (en) 2007-06-27
CN1259141B (zh) 2013-03-27
DE69837992T2 (de) 2008-03-20
PL336714A1 (en) 2000-07-03
CZ297371B6 (cs) 2006-11-15
KR20010012337A (ko) 2001-02-15

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