[go: up one dir, main page]

ES2122921B1 - Proteinas recombinantes de fusion del virus reproductivo y respiratorio porcino (prrsv) y su empleo en diagnostico. - Google Patents

Proteinas recombinantes de fusion del virus reproductivo y respiratorio porcino (prrsv) y su empleo en diagnostico.

Info

Publication number
ES2122921B1
ES2122921B1 ES09602770A ES9602770A ES2122921B1 ES 2122921 B1 ES2122921 B1 ES 2122921B1 ES 09602770 A ES09602770 A ES 09602770A ES 9602770 A ES9602770 A ES 9602770A ES 2122921 B1 ES2122921 B1 ES 2122921B1
Authority
ES
Spain
Prior art keywords
prrsv
fusion proteins
diagnosis
recombinant fusion
porcine reproductive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES09602770A
Other languages
English (en)
Other versions
ES2122921A1 (es
Inventor
Maria Jose Rodriguez
Antonio Sanz
Jose Ignacio Casal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inmunologia y Genetica Aplicada SA
Original Assignee
Inmunologia y Genetica Aplicada SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8297194&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2122921(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Inmunologia y Genetica Aplicada SA filed Critical Inmunologia y Genetica Aplicada SA
Priority to ES09602770A priority Critical patent/ES2122921B1/es
Priority to PCT/ES1997/000313 priority patent/WO1998029550A1/es
Priority to EP97947734A priority patent/EP0952219B1/en
Priority to DK97947734T priority patent/DK0952219T3/da
Priority to CA2276086A priority patent/CA2276086C/en
Priority to US09/331,924 priority patent/US6468538B1/en
Priority to AU53988/98A priority patent/AU722732B2/en
Priority to ES97947734T priority patent/ES2255114T3/es
Priority to AT97947734T priority patent/ATE312925T1/de
Priority to DE69734893T priority patent/DE69734893T2/de
Publication of ES2122921A1 publication Critical patent/ES2122921A1/es
Publication of ES2122921B1 publication Critical patent/ES2122921B1/es
Application granted granted Critical
Priority to US10/147,951 priority patent/US6592870B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/10011—Arteriviridae
    • C12N2770/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/165—Coronaviridae, e.g. avian infectious bronchitis virus
    • G01N2333/17—Porcine transmissible gastroenteritis virus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROTEINAS RECOMBINANTES DE FUSION DEL VIRUS DEL SINDROME REPRODUCTIVO Y RESPIRATORIO PORCINO (PRRSV) Y SU EMPLEO EN DIAGNOSTICO. LAS PROTEINAS RECOMBINANTES DE FUSION COMPRENDEN LA PROTEINA DE LA NUCLEOCAPSIDA DEL VIRUS DEL SINDROME REPRODUCTIVO Y RESPIRATORIO PORCINO (PRRSV), OBTENIDA TANTO A PARTIR DE UN AISLADO EUROPEO DE PRRSV COMO DE UN AISLADO AMERICANO, FUSIONADA A UNA SECUENCIA DE AMINOACIDOS DERIVADA DEL SISTEMA ELEGIDO PARA LA EXPRESION DE DICHA PROTEINA RECOMBINANTE DE FUSION BIEN DIRECTAMENTE O BIEN A TRAVES DE UNA ZONA DE UNION FORMADA POR UN NUMERO PEQUEÑO DE AMINOACIDOS. ESTAS PROTEINAS RECOMBINANTES DE FUSION SON ADECUADAS PARA SU EMPLEO EN EL DIAGNOSTICO DE PRRSV.
ES09602770A 1996-12-30 1996-12-30 Proteinas recombinantes de fusion del virus reproductivo y respiratorio porcino (prrsv) y su empleo en diagnostico. Expired - Fee Related ES2122921B1 (es)

Priority Applications (11)

Application Number Priority Date Filing Date Title
ES09602770A ES2122921B1 (es) 1996-12-30 1996-12-30 Proteinas recombinantes de fusion del virus reproductivo y respiratorio porcino (prrsv) y su empleo en diagnostico.
AU53988/98A AU722732B2 (en) 1996-12-30 1997-12-24 Recombinant fusion proteins of the porcine reproductive and respiratory syndrome virus (PRRSV) and its use in diagnosis
AT97947734T ATE312925T1 (de) 1996-12-30 1997-12-24 Rekombinante fusionsproteine des reproduktiven und respiratorischen syndrom virus aus dem schwein (prrsv) und deren verwendung in der diagnose
DK97947734T DK0952219T3 (da) 1996-12-30 1997-12-24 Rekombinante fusionsproteiner fra porcint reproduktivt og respiratorisk syndrom virus (PRRSV) og dets anvendelse i diagnosen
CA2276086A CA2276086C (en) 1996-12-30 1997-12-24 Recombinant fusion proteins of the porcine reproductive and respiratory syndrome virus (prrsv) and its use in diagnosis
US09/331,924 US6468538B1 (en) 1996-12-30 1997-12-24 Recombinant proteins for the fusion of the porcine reproductive and respiratory syndrome virus and its use in diagnosis
PCT/ES1997/000313 WO1998029550A1 (es) 1996-12-30 1997-12-24 Proteinas recombinantes de fusion del virus del sindrome reproductivo y respiratorio porcino (prrsv) y su empleo en diagnostico
ES97947734T ES2255114T3 (es) 1996-12-30 1997-12-24 Proteinas recombinantes de fusion del virus del sindrome reproductivo y respiratorio porcio (prrsv) y su empleo en diagnostico.
EP97947734A EP0952219B1 (en) 1996-12-30 1997-12-24 Recombinant fusion proteins of the porcine reproductive and respiratory syndrome virus (PRRSV) and its use in diagnosis
DE69734893T DE69734893T2 (de) 1996-12-30 1997-12-24 Rekombinante fusionsproteine des reproduktiven und respiratorischen syndrom virus aus dem schwein (prrsv) und deren verwendung in der diagnose
US10/147,951 US6592870B2 (en) 1996-12-30 2002-05-17 Method and kit using recombinant proteins in fusion of porcine reproductive and respiratory syndrome virus and for diagnosis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09602770A ES2122921B1 (es) 1996-12-30 1996-12-30 Proteinas recombinantes de fusion del virus reproductivo y respiratorio porcino (prrsv) y su empleo en diagnostico.

Publications (2)

Publication Number Publication Date
ES2122921A1 ES2122921A1 (es) 1998-12-16
ES2122921B1 true ES2122921B1 (es) 1999-09-16

Family

ID=8297194

Family Applications (2)

Application Number Title Priority Date Filing Date
ES09602770A Expired - Fee Related ES2122921B1 (es) 1996-12-30 1996-12-30 Proteinas recombinantes de fusion del virus reproductivo y respiratorio porcino (prrsv) y su empleo en diagnostico.
ES97947734T Expired - Lifetime ES2255114T3 (es) 1996-12-30 1997-12-24 Proteinas recombinantes de fusion del virus del sindrome reproductivo y respiratorio porcio (prrsv) y su empleo en diagnostico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES97947734T Expired - Lifetime ES2255114T3 (es) 1996-12-30 1997-12-24 Proteinas recombinantes de fusion del virus del sindrome reproductivo y respiratorio porcio (prrsv) y su empleo en diagnostico.

Country Status (9)

Country Link
US (2) US6468538B1 (es)
EP (1) EP0952219B1 (es)
AT (1) ATE312925T1 (es)
AU (1) AU722732B2 (es)
CA (1) CA2276086C (es)
DE (1) DE69734893T2 (es)
DK (1) DK0952219T3 (es)
ES (2) ES2122921B1 (es)
WO (1) WO1998029550A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE365746T1 (de) * 1997-05-06 2007-07-15 Boehringer Ingelheim Vetmed Prrsv-antigene, die auf peptidsequenzen des prrs- virus basieren, für die verwendung als impfstoff und für diagnostische tests
US6754889B1 (en) * 2000-10-04 2004-06-22 Compuware Corporation Java automation, testing, and analysis
KR20130105750A (ko) 2005-02-25 2013-09-25 아이덱스 래보러토리즈, 인코포레이티드 돼지 생식기 호흡기 증후군 바이러스에 대한 항체를 검출하기 위한 펩티드
ES2311423B1 (es) 2007-07-27 2010-01-07 Inmunologia Y Genetica Aplicada, S.A. Inmunoensayo de doble reconocimiento para la deteccion de anticuerpos.
KR101258611B1 (ko) * 2011-01-07 2013-04-26 유한회사 바이오노트 북미형 및 유럽형 ｐｒｒｓｖ 항원을 포함하는 분리된 단백질 및 그의 용도
CN104330572A (zh) * 2014-10-27 2015-02-04 苏州市吴江区畜牧兽医站 一种用于间接ELISA检测猪PRRSV病毒IgG或IgA抗体的试剂盒
CN108653194B (zh) * 2018-07-06 2020-09-29 中国科学院微生物研究所 一种以融合干扰素为活性成分的嚼糖剂型药物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK53595A (da) * 1994-05-13 1995-11-14 Iberica Cyanamid Rekombinante PRRSV-proteiner, diagnostiske kits og vaccine indeholdende sådanne rekombinante PRRSV-proteiner

Also Published As

Publication number Publication date
DE69734893T2 (de) 2006-08-24
AU722732B2 (en) 2000-08-10
EP0952219A1 (en) 1999-10-27
WO1998029550A1 (es) 1998-07-09
ES2255114T3 (es) 2006-06-16
DK0952219T3 (da) 2006-05-01
ES2122921A1 (es) 1998-12-16
AU5398898A (en) 1998-07-31
US6468538B1 (en) 2002-10-22
US20030108570A1 (en) 2003-06-12
CA2276086A1 (en) 1998-07-09
US6592870B2 (en) 2003-07-15
ATE312925T1 (de) 2005-12-15
EP0952219B1 (en) 2005-12-14
DE69734893D1 (de) 2006-01-19
CA2276086C (en) 2015-05-19

Similar Documents

Publication Publication Date Title
ITTO950367A0 (it) Proteine di prrsv ricombinanti, corredi diagnostici e vaccini contenenti tali proteine di prrsv ricombinanti.
ES2077666T3 (es) Proteina de union a fibronectina y su preparacion.
ES2149149T1 (es) Proteinas de fijacion de interleuquina-18, su preparacion y utilizacion.
EE200100223A (et) Interferoon-beetaga sulandatud valgud ja nende kasutamine
EA200001023A1 (ru) Специфическое в отношении fapa-(протеин альфа активации фибробласта) антитело с повышенной продуктивностью
NO821111L (no) Radioaktivt merkede peptider
ATE517922T1 (de) Stabilisierte einzel-domänen-antikörper in einer pharmazeutischen zusammensetzung ausgestaltet für inhalation
DE69823046D1 (de) Praktische in vitro sialylierung von rekombinanten glykpproteinen
DE69807679D1 (de) Zusammensetzungen aus konjugaten des stabilen, aktiven, menschlichen ob proteins mit der fc kette von immunoglobulinen und damit zusammenhängende verfahren
NZ512083A (en) Methods of increasing lean tissue mass using OB protein compositions
DE69632658D1 (de) Expression in der selben Zelle von Polypeptide vom schweinen reproduktiven und respiratorischen Syndrom
ES2046462T3 (es) Marcadores de activacion de celulas "t".
ATE368053T1 (de) Antimikrobielle peptide
BR9811094A (pt) Agente terapêutico para tumores linfáticos
ATE199377T1 (de) Protein mit cytokinaktivität, rekombinant-dns, expressionsvektor und wirtszellen zu seiner herstellung
SE9403526D0 (sv) New Peptides
ES2122921B1 (es) Proteinas recombinantes de fusion del virus reproductivo y respiratorio porcino (prrsv) y su empleo en diagnostico.
DE69714451D1 (de) Prionbindende proteine und deren verwendungen
DE69704269D1 (de) Dendritische, lysinhaltige Polypeptide zur gezielten Arzneimittelabreichung
DE60043070D1 (de) Proteine-abgabe durch polare epithelzellen schichte
ES2080023B1 (es) Capsidas y proteinas recombinantes del virus de la enfermedad hemorragica del conejo (rhdv), kits de diagnostico y vacunas que contienen dichos productos recombinantes.
DE59608073D1 (de) Antikörper gegen ein, einen histidin-anteil aufweisendes fusionspolypeptid
AR245958A1 (es) Procedimiento para la preparacion de polipeptidos de interleucina-1alfa
TR200002611T2 (tr) Beta-lipotropin ve kullanımları
EP1103561A4 (en) HLA-A2 RESTRICTED TUMORANTIGEN PEPTIDE DERIVED FROM SART-1

Legal Events

Date Code Title Description
EC2A Search report published

Date of ref document: 19981216

Kind code of ref document: A1

Effective date: 19981216

FD2A Announcement of lapse in spain

Effective date: 20180807