HUE067047T2 - Humán antitest aggrekanáz típusú ADAMTS specieszek ellen aggrekanázzal kapcsolatos betegségek terápiájára - Google Patents
Humán antitest aggrekanáz típusú ADAMTS specieszek ellen aggrekanázzal kapcsolatos betegségek terápiájáraInfo
- Publication number
- HUE067047T2 HUE067047T2 HUE14853737A HUE14853737A HUE067047T2 HU E067047 T2 HUE067047 T2 HU E067047T2 HU E14853737 A HUE14853737 A HU E14853737A HU E14853737 A HUE14853737 A HU E14853737A HU E067047 T2 HUE067047 T2 HU E067047T2
- Authority
- HU
- Hungary
- Prior art keywords
- aggrecanase
- therapy
- human antibody
- antibody against
- related diseases
- Prior art date
Links
- 102000029750 ADAMTS Human genes 0.000 title 1
- 108091022879 ADAMTS Proteins 0.000 title 1
- 108010003059 aggrecanase Proteins 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361891087P | 2013-10-15 | 2013-10-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE067047T2 true HUE067047T2 (hu) | 2024-09-28 |
Family
ID=52828245
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE14853737A HUE067047T2 (hu) | 2013-10-15 | 2014-10-14 | Humán antitest aggrekanáz típusú ADAMTS specieszek ellen aggrekanázzal kapcsolatos betegségek terápiájára |
Country Status (19)
Country | Link |
---|---|
US (2) | US20160304622A1 (hu) |
EP (1) | EP3057992B1 (hu) |
JP (1) | JP6454893B2 (hu) |
CN (1) | CN105849128B (hu) |
AU (1) | AU2014335251B2 (hu) |
CA (1) | CA2927525C (hu) |
DK (1) | DK3057992T3 (hu) |
ES (1) | ES2983249T3 (hu) |
FI (1) | FI3057992T3 (hu) |
HR (1) | HRP20240951T1 (hu) |
HU (1) | HUE067047T2 (hu) |
LT (1) | LT3057992T (hu) |
PL (1) | PL3057992T3 (hu) |
PT (1) | PT3057992T (hu) |
RS (1) | RS65724B1 (hu) |
SI (1) | SI3057992T1 (hu) |
SM (1) | SMT202400288T1 (hu) |
WO (1) | WO2015056808A1 (hu) |
ZA (1) | ZA201603098B (hu) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI825021B (zh) | 2017-06-02 | 2023-12-11 | 德商麥克專利有限公司 | 與mmp13結合之免疫球蛋白 |
PL3630847T3 (pl) * | 2017-06-02 | 2025-02-03 | Merck Patent Gmbh | Immunoglobuliny wiążące adamts |
KR20250005464A (ko) * | 2017-06-02 | 2025-01-09 | 메르크 파텐트 게엠베하 | Adamts5, mmp13 및 아그레칸 결합성 폴리펩타이드 |
TWI811220B (zh) * | 2017-06-02 | 2023-08-11 | 比利時商艾伯林克斯公司 | 結合聚集蛋白聚糖之免疫球蛋白 |
WO2020097627A1 (en) * | 2018-11-09 | 2020-05-14 | University Of Massachusetts | Anti-cfae antibodies and methods of use |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
US5156840A (en) | 1982-03-09 | 1992-10-20 | Cytogen Corporation | Amine-containing porphyrin derivatives |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
HUT35524A (en) | 1983-08-02 | 1985-07-29 | Hoechst Ag | Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance |
US5057313A (en) | 1986-02-25 | 1991-10-15 | The Center For Molecular Medicine And Immunology | Diagnostic and therapeutic antibody conjugates |
KR100261941B1 (ko) | 1994-07-13 | 2000-07-15 | 나가야마 오사무 | 사람의 인터루킨-8에 대한 재구성 사람항체 |
CN100335501C (zh) | 1996-09-26 | 2007-09-05 | 中外制药株式会社 | 抗人副甲状腺激素相关蛋白的抗体 |
MXPA05000959A (es) | 2002-07-29 | 2005-05-16 | Wyeth Corp | Moleculas adamts4 modificadas y metodo de uso de las mismas. |
JP2004244339A (ja) * | 2003-02-12 | 2004-09-02 | Tsunaharu Matsushima | Adamts4の機能阻害剤 |
JP4464395B2 (ja) | 2003-03-05 | 2010-05-19 | ヘイローザイム インコーポレイテッド | 可溶性ヒアルロニダーゼ糖タンパク質(sHASEGP)、その調製プロセス、使用およびそれを含む薬学的組成物 |
AU2005214382B2 (en) | 2004-02-19 | 2011-08-04 | Genentech, Inc. | CDR-repaired antibodies |
CN1981049A (zh) * | 2004-04-16 | 2007-06-13 | 惠氏公司 | 截短的adamts分子 |
TW201114436A (en) * | 2009-07-02 | 2011-05-01 | Glaxo Group Ltd | Polypeptides and method of treatment |
WO2013109829A1 (en) * | 2012-01-20 | 2013-07-25 | Glaxosmithkline Intellectual Property Development Ltd | Anti-adamts4 antibodies and methods of treatment |
-
2014
- 2014-10-14 DK DK14853737.6T patent/DK3057992T3/da active
- 2014-10-14 FI FIEP14853737.6T patent/FI3057992T3/fi active
- 2014-10-14 SM SM20240288T patent/SMT202400288T1/it unknown
- 2014-10-14 HR HRP20240951TT patent/HRP20240951T1/hr unknown
- 2014-10-14 US US15/029,823 patent/US20160304622A1/en not_active Abandoned
- 2014-10-14 AU AU2014335251A patent/AU2014335251B2/en active Active
- 2014-10-14 SI SI201432088T patent/SI3057992T1/sl unknown
- 2014-10-14 HU HUE14853737A patent/HUE067047T2/hu unknown
- 2014-10-14 JP JP2016524160A patent/JP6454893B2/ja active Active
- 2014-10-14 EP EP14853737.6A patent/EP3057992B1/en active Active
- 2014-10-14 CA CA2927525A patent/CA2927525C/en active Active
- 2014-10-14 ES ES14853737T patent/ES2983249T3/es active Active
- 2014-10-14 WO PCT/JP2014/077767 patent/WO2015056808A1/en active Application Filing
- 2014-10-14 PT PT148537376T patent/PT3057992T/pt unknown
- 2014-10-14 RS RS20240767A patent/RS65724B1/sr unknown
- 2014-10-14 CN CN201480056880.2A patent/CN105849128B/zh active Active
- 2014-10-14 PL PL14853737.6T patent/PL3057992T3/pl unknown
- 2014-10-14 LT LTEPPCT/JP2014/077767T patent/LT3057992T/lt unknown
-
2016
- 2016-05-09 ZA ZA2016/03098A patent/ZA201603098B/en unknown
-
2018
- 2018-10-05 US US16/153,413 patent/US10640573B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
US20160304622A1 (en) | 2016-10-20 |
HRP20240951T1 (hr) | 2024-10-11 |
EP3057992A4 (en) | 2017-05-31 |
AU2014335251B2 (en) | 2020-04-30 |
CN105849128A (zh) | 2016-08-10 |
EP3057992A1 (en) | 2016-08-24 |
US10640573B2 (en) | 2020-05-05 |
SI3057992T1 (sl) | 2024-09-30 |
RS65724B1 (sr) | 2024-08-30 |
EP3057992B1 (en) | 2024-04-17 |
JP2016538839A (ja) | 2016-12-15 |
ZA201603098B (en) | 2020-12-23 |
US20190233541A1 (en) | 2019-08-01 |
AU2014335251A1 (en) | 2016-06-02 |
LT3057992T (lt) | 2024-07-25 |
DK3057992T3 (da) | 2024-07-22 |
SMT202400288T1 (it) | 2024-09-16 |
JP6454893B2 (ja) | 2019-01-23 |
CN105849128B (zh) | 2019-10-11 |
CA2927525C (en) | 2023-01-31 |
PT3057992T (pt) | 2024-07-10 |
FI3057992T3 (fi) | 2024-07-09 |
WO2015056808A1 (en) | 2015-04-23 |
ES2983249T3 (es) | 2024-10-22 |
CA2927525A1 (en) | 2015-04-23 |
PL3057992T3 (pl) | 2024-08-26 |
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