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HUE067047T2 - Humán antitest aggrekanáz típusú ADAMTS specieszek ellen aggrekanázzal kapcsolatos betegségek terápiájára - Google Patents

Humán antitest aggrekanáz típusú ADAMTS specieszek ellen aggrekanázzal kapcsolatos betegségek terápiájára

Info

Publication number
HUE067047T2
HUE067047T2 HUE14853737A HUE14853737A HUE067047T2 HU E067047 T2 HUE067047 T2 HU E067047T2 HU E14853737 A HUE14853737 A HU E14853737A HU E14853737 A HUE14853737 A HU E14853737A HU E067047 T2 HUE067047 T2 HU E067047T2
Authority
HU
Hungary
Prior art keywords
aggrecanase
therapy
human antibody
antibody against
related diseases
Prior art date
Application number
HUE14853737A
Other languages
English (en)
Inventor
Akira Miyakoshi
Mikiko Nakamura
Kanehisa Kojoh
Satsuki Mochizuki
Yasunori Okada
Original Assignee
Genefrontier Corp
Univ Keio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genefrontier Corp, Univ Keio filed Critical Genefrontier Corp
Publication of HUE067047T2 publication Critical patent/HUE067047T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HUE14853737A 2013-10-15 2014-10-14 Humán antitest aggrekanáz típusú ADAMTS specieszek ellen aggrekanázzal kapcsolatos betegségek terápiájára HUE067047T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361891087P 2013-10-15 2013-10-15

Publications (1)

Publication Number Publication Date
HUE067047T2 true HUE067047T2 (hu) 2024-09-28

Family

ID=52828245

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE14853737A HUE067047T2 (hu) 2013-10-15 2014-10-14 Humán antitest aggrekanáz típusú ADAMTS specieszek ellen aggrekanázzal kapcsolatos betegségek terápiájára

Country Status (19)

Country Link
US (2) US20160304622A1 (hu)
EP (1) EP3057992B1 (hu)
JP (1) JP6454893B2 (hu)
CN (1) CN105849128B (hu)
AU (1) AU2014335251B2 (hu)
CA (1) CA2927525C (hu)
DK (1) DK3057992T3 (hu)
ES (1) ES2983249T3 (hu)
FI (1) FI3057992T3 (hu)
HR (1) HRP20240951T1 (hu)
HU (1) HUE067047T2 (hu)
LT (1) LT3057992T (hu)
PL (1) PL3057992T3 (hu)
PT (1) PT3057992T (hu)
RS (1) RS65724B1 (hu)
SI (1) SI3057992T1 (hu)
SM (1) SMT202400288T1 (hu)
WO (1) WO2015056808A1 (hu)
ZA (1) ZA201603098B (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI825021B (zh) 2017-06-02 2023-12-11 德商麥克專利有限公司 與mmp13結合之免疫球蛋白
PL3630847T3 (pl) * 2017-06-02 2025-02-03 Merck Patent Gmbh Immunoglobuliny wiążące adamts
KR20250005464A (ko) * 2017-06-02 2025-01-09 메르크 파텐트 게엠베하 Adamts5, mmp13 및 아그레칸 결합성 폴리펩타이드
TWI811220B (zh) * 2017-06-02 2023-08-11 比利時商艾伯林克斯公司 結合聚集蛋白聚糖之免疫球蛋白
WO2020097627A1 (en) * 2018-11-09 2020-05-14 University Of Massachusetts Anti-cfae antibodies and methods of use

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
US5156840A (en) 1982-03-09 1992-10-20 Cytogen Corporation Amine-containing porphyrin derivatives
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
HUT35524A (en) 1983-08-02 1985-07-29 Hoechst Ag Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
US5057313A (en) 1986-02-25 1991-10-15 The Center For Molecular Medicine And Immunology Diagnostic and therapeutic antibody conjugates
KR100261941B1 (ko) 1994-07-13 2000-07-15 나가야마 오사무 사람의 인터루킨-8에 대한 재구성 사람항체
CN100335501C (zh) 1996-09-26 2007-09-05 中外制药株式会社 抗人副甲状腺激素相关蛋白的抗体
MXPA05000959A (es) 2002-07-29 2005-05-16 Wyeth Corp Moleculas adamts4 modificadas y metodo de uso de las mismas.
JP2004244339A (ja) * 2003-02-12 2004-09-02 Tsunaharu Matsushima Adamts4の機能阻害剤
JP4464395B2 (ja) 2003-03-05 2010-05-19 ヘイローザイム インコーポレイテッド 可溶性ヒアルロニダーゼ糖タンパク質(sHASEGP)、その調製プロセス、使用およびそれを含む薬学的組成物
AU2005214382B2 (en) 2004-02-19 2011-08-04 Genentech, Inc. CDR-repaired antibodies
CN1981049A (zh) * 2004-04-16 2007-06-13 惠氏公司 截短的adamts分子
TW201114436A (en) * 2009-07-02 2011-05-01 Glaxo Group Ltd Polypeptides and method of treatment
WO2013109829A1 (en) * 2012-01-20 2013-07-25 Glaxosmithkline Intellectual Property Development Ltd Anti-adamts4 antibodies and methods of treatment

Also Published As

Publication number Publication date
US20160304622A1 (en) 2016-10-20
HRP20240951T1 (hr) 2024-10-11
EP3057992A4 (en) 2017-05-31
AU2014335251B2 (en) 2020-04-30
CN105849128A (zh) 2016-08-10
EP3057992A1 (en) 2016-08-24
US10640573B2 (en) 2020-05-05
SI3057992T1 (sl) 2024-09-30
RS65724B1 (sr) 2024-08-30
EP3057992B1 (en) 2024-04-17
JP2016538839A (ja) 2016-12-15
ZA201603098B (en) 2020-12-23
US20190233541A1 (en) 2019-08-01
AU2014335251A1 (en) 2016-06-02
LT3057992T (lt) 2024-07-25
DK3057992T3 (da) 2024-07-22
SMT202400288T1 (it) 2024-09-16
JP6454893B2 (ja) 2019-01-23
CN105849128B (zh) 2019-10-11
CA2927525C (en) 2023-01-31
PT3057992T (pt) 2024-07-10
FI3057992T3 (fi) 2024-07-09
WO2015056808A1 (en) 2015-04-23
ES2983249T3 (es) 2024-10-22
CA2927525A1 (en) 2015-04-23
PL3057992T3 (pl) 2024-08-26

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