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HUE055742T2 - Gyorsan ható inzulin készítmények - Google Patents

Gyorsan ható inzulin készítmények

Info

Publication number
HUE055742T2
HUE055742T2 HUE19161129A HUE19161129A HUE055742T2 HU E055742 T2 HUE055742 T2 HU E055742T2 HU E19161129 A HUE19161129 A HU E19161129A HU E19161129 A HUE19161129 A HU E19161129A HU E055742 T2 HUE055742 T2 HU E055742T2
Authority
HU
Hungary
Prior art keywords
rapid
acting insulin
insulin compositions
compositions
acting
Prior art date
Application number
HUE19161129A
Other languages
English (en)
Inventor
Michael Edward Christe
Thomas Andrew Hardy
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53189204&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE055742(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HUE055742T2 publication Critical patent/HUE055742T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A61K31/5585Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes having five-membered rings containing oxygen as the only ring hetero atom, e.g. prostacyclin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
HUE19161129A 2014-05-08 2015-05-04 Gyorsan ható inzulin készítmények HUE055742T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461990402P 2014-05-08 2014-05-08

Publications (1)

Publication Number Publication Date
HUE055742T2 true HUE055742T2 (hu) 2021-12-28

Family

ID=53189204

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE15723388 HUE044370T2 (hu) 2014-05-08 2015-05-04 Gyorsan ható inzulin készítmények
HUE19161129A HUE055742T2 (hu) 2014-05-08 2015-05-04 Gyorsan ható inzulin készítmények

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HUE15723388 HUE044370T2 (hu) 2014-05-08 2015-05-04 Gyorsan ható inzulin készítmények

Country Status (36)

Country Link
US (2) US9439952B2 (hu)
EP (3) EP3943155A1 (hu)
JP (1) JP6050902B2 (hu)
KR (1) KR101858890B1 (hu)
CN (1) CN106456717B (hu)
AP (1) AP2016009525A0 (hu)
AR (1) AR100155A1 (hu)
AU (1) AU2015256355B2 (hu)
BR (1) BR112016024357B1 (hu)
CA (1) CA2945188C (hu)
CL (1) CL2016002772A1 (hu)
CY (2) CY1121669T1 (hu)
DK (2) DK3536380T3 (hu)
EA (1) EA031134B1 (hu)
ES (2) ES2891983T3 (hu)
HR (2) HRP20190777T1 (hu)
HU (2) HUE044370T2 (hu)
IL (1) IL248350B (hu)
JO (1) JO3624B1 (hu)
LT (2) LT3140008T (hu)
MA (1) MA39441A1 (hu)
ME (1) ME03384B (hu)
MX (1) MX367521B (hu)
NZ (1) NZ724919A (hu)
PE (1) PE20161408A1 (hu)
PH (1) PH12016502195B1 (hu)
PL (2) PL3536380T3 (hu)
PT (2) PT3140008T (hu)
RS (2) RS62291B1 (hu)
SG (1) SG11201608424WA (hu)
SI (2) SI3536380T1 (hu)
TN (1) TN2016000443A1 (hu)
TR (1) TR201906843T4 (hu)
TW (1) TWI685348B (hu)
UA (1) UA124919C2 (hu)
WO (1) WO2015171484A1 (hu)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE032287T2 (hu) 2008-03-18 2017-09-28 Novo Nordisk As Proteáz-stabilizált, acilált inzulin-analógok
CN107952065A (zh) 2012-11-13 2018-04-24 阿道恰公司 包含经取代阴离子化合物的速效胰岛素制剂
ES2805367T3 (es) 2013-01-11 2021-02-11 Corsair Pharma Inc Profármacos de treprostinil
US9505737B2 (en) 2013-01-11 2016-11-29 Corsair Pharma, Inc. Treprostinil derivative compounds and methods of using same
ES2972423T3 (es) * 2015-07-28 2024-06-12 Lilly Co Eli Preparado farmacéutico para mejorar la absorción y la acción hipoglucemiante postprandial de la insulina
JO3749B1 (ar) * 2015-08-27 2021-01-31 Lilly Co Eli تركيبات إنسولين سريعة المفعول
AU2017211410B2 (en) * 2016-01-29 2022-10-13 Mannkind Corporation Dry powder inhaler
GB201607918D0 (en) 2016-05-06 2016-06-22 Arecor Ltd Novel formulations
JP7220650B2 (ja) 2016-09-26 2023-02-10 ユナイテッド セラピューティクス コーポレイション トレプロスチニルプロドラッグ
CN109803639B (zh) 2016-09-29 2024-01-02 艾瑞克有限公司 新制剂
WO2018109162A1 (en) 2016-12-16 2018-06-21 Novo Nordisk A/S Insulin containing pharmaceutical compositions
GB201707187D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
GB201707188D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
GB201707189D0 (en) 2017-05-05 2017-06-21 Arecor Ltd Novel formulations
CR20190522A (es) 2017-06-01 2020-01-15 Lilly Co Eli Composiciones de insulina de rápida acción
IL277731B2 (en) * 2018-04-04 2024-03-01 Arecor Ltd Medical infusion pump system for the delivery of an insulin compound
EP3773474A1 (en) 2018-04-04 2021-02-17 Arecor Limited Medical infusion pump system for the delivery of an insulin compound
WO2019193351A1 (en) 2018-04-04 2019-10-10 Arecor Limited Medical infusion pump system for the delivery of an insulin compound
WO2019243627A1 (fr) 2018-06-23 2019-12-26 Adocia Dispositif pour injecter une solution d'insuline(s)
FR3083985A1 (fr) 2018-07-23 2020-01-24 Adocia Dispositif pour injecter une solution d'insuline(s)
BR112021002200B1 (pt) 2018-09-18 2024-03-12 Eli Lilly And Company Sal erbumina de trepostinila
US10799564B1 (en) * 2019-05-06 2020-10-13 Baxter International Inc. Insulin premix formulation and product, methods of preparing same, and methods of using same
WO2021009027A1 (en) * 2019-07-12 2021-01-21 Novo Nordisk A/S High concentration insulin formulation
EP4017588A1 (en) 2019-08-23 2022-06-29 United Therapeutics Corporation Treprostinil prodrugs
GB202004814D0 (en) 2020-04-01 2020-05-13 Arecor Ltd Novel formulations
JP2023523557A (ja) 2020-04-17 2023-06-06 ユナイテッド セラピューティクス コーポレイション 間質性肺疾患の治療における使用のためのトレプロスチニル
CA3180230A1 (en) 2020-06-09 2021-12-16 Hitesh Batra Fumaryl diketopiperidine prodrugs of treprostinil
WO2022002008A1 (zh) * 2020-06-30 2022-01-06 江苏恒瑞医药股份有限公司 速效胰岛素组合物及其医药用途
AU2021401921A1 (en) 2020-12-14 2023-07-06 United Therapeutics Corporation Methods of treating disease with treprostinil prodrugs
IL305510A (en) 2021-03-03 2023-10-01 United Therapeutics Corp A dry powder preparation of terprostinil and its prodrug that will additionally contain (E)-3,6-bis[4-(N-carbonyl-2-propenyl)amidobiotyl]-2,5-dictopiperazine (FDKP)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2740953A1 (de) 1977-09-12 1979-03-22 Thera Ges Fuer Patente Verwendung von prostaglandinen zur senkung des blutzuckerspiegels
JPH10251146A (ja) 1997-03-11 1998-09-22 Toray Ind Inc 糖尿病性神経障害の治療方法
US7238663B2 (en) * 2001-08-28 2007-07-03 Eli Lilly And Company Pre-mixes of GLP-1 and basal insulin
ES2360182T3 (es) * 2002-05-07 2011-06-01 Novo Nordisk A/S Formulaciones solubles que comprenden insulina monomérica e insulina acilada.
CA2562614C (en) * 2004-04-12 2013-09-17 United Therapeutics, Inc. Use of treprostinil to treat neuropathic diabetic foot ulcers
CA2697057A1 (en) * 2007-08-22 2009-02-26 Gilead Colorado, Inc. Therapy for complications of diabetes
DK2626093T3 (en) 2008-08-28 2014-02-24 Hoffmann La Roche DEVICE FOR INCREASING HYPODERMIC insulin absorption
CA2737350A1 (en) * 2008-09-25 2010-04-01 Aradigm Corporation Deep lung pulmonary delivery of treprostinil
RU2533217C3 (ru) 2009-06-26 2020-12-21 Ново Нордиск А/С Препарат, содержащий инсулин, никотинамид и аминокислоту
BR112012011237A2 (pt) * 2009-11-13 2019-09-24 Univ Tokyo agente terapêutico e profilático para diabetes
CA2821613A1 (en) 2010-12-14 2012-06-21 Novo Nordisk A/S Preparation comprising insulin, nicotinamide and an amino acid
JP6092867B2 (ja) * 2011-08-12 2017-03-08 アセンディス ファーマ エー/エス 担体連結しているトレプロスチニルプロドラッグ
US9381247B2 (en) * 2012-04-16 2016-07-05 Biodel Inc. Magnesium compositions for modulating the pharmacokinetics and pharmacodynamics of insulin and insulin analogs, and injection site pain
WO2015031709A1 (en) 2013-08-30 2015-03-05 Perosphere, Inc. Rapid acting injectable formulations comprising a peptide and a vasodilatory agent
US20150273022A1 (en) 2014-02-10 2015-10-01 Biodel Inc. Stabilized ultra-rapid-acting insulin formulations

Also Published As

Publication number Publication date
HRP20211415T1 (hr) 2021-12-10
DK3536380T3 (da) 2021-08-02
DK3140008T3 (da) 2019-06-24
PL3140008T3 (pl) 2019-09-30
MX367521B (es) 2019-08-26
ES2733639T3 (es) 2019-12-02
MA39441A1 (fr) 2017-06-30
BR112016024357B1 (pt) 2022-08-23
HUE044370T2 (hu) 2019-10-28
KR101858890B1 (ko) 2018-05-16
IL248350B (en) 2020-03-31
CY1124454T1 (el) 2022-07-22
JO3624B1 (ar) 2020-08-27
SI3140008T1 (sl) 2019-06-28
ME03384B (me) 2020-01-20
TN2016000443A1 (en) 2018-04-04
EP3536380B8 (en) 2021-09-22
KR20160133567A (ko) 2016-11-22
UA124919C2 (uk) 2021-12-15
PH12016502195A1 (en) 2017-02-06
IL248350A0 (en) 2016-11-30
EA031134B1 (ru) 2018-11-30
LT3140008T (lt) 2019-05-27
AP2016009525A0 (en) 2016-10-31
BR112016024357A2 (pt) 2017-10-10
RS62291B1 (sr) 2021-09-30
ES2891983T3 (es) 2022-02-01
JP2016523807A (ja) 2016-08-12
AR100155A1 (es) 2016-09-14
LT3536380T (lt) 2021-08-10
PT3536380T (pt) 2021-09-02
CA2945188C (en) 2018-12-11
PT3140008T (pt) 2019-06-25
SI3536380T1 (sl) 2021-09-30
AU2015256355A1 (en) 2016-10-27
PH12016502195B1 (en) 2017-02-06
TW201625291A (zh) 2016-07-16
AU2015256355B2 (en) 2017-09-14
MX2016014643A (es) 2017-03-06
HRP20190777T1 (hr) 2019-08-23
CL2016002772A1 (es) 2017-06-09
WO2015171484A1 (en) 2015-11-12
CY1121669T1 (el) 2020-07-31
US20160367640A1 (en) 2016-12-22
CN106456717A (zh) 2017-02-22
US20160129087A1 (en) 2016-05-12
EP3140008A1 (en) 2017-03-15
EP3536380A1 (en) 2019-09-11
TWI685348B (zh) 2020-02-21
PE20161408A1 (es) 2016-12-28
JP6050902B2 (ja) 2016-12-21
PL3536380T3 (pl) 2021-12-27
NZ724919A (en) 2018-01-26
US9439952B2 (en) 2016-09-13
EP3536380B1 (en) 2021-07-07
TR201906843T4 (tr) 2019-05-21
EA201691911A1 (ru) 2017-02-28
RS58726B1 (sr) 2019-06-28
CA2945188A1 (en) 2015-11-12
SG11201608424WA (en) 2016-11-29
EP3140008B1 (en) 2019-04-17
EP3943155A1 (en) 2022-01-26
US10172922B2 (en) 2019-01-08
CN106456717B (zh) 2020-01-17

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