[go: up one dir, main page]

HUE050049T2 - Szennyezõanyagok elválasztása streptococcus pneumoniae poliszacharidtól PH manipulációjával - Google Patents

Szennyezõanyagok elválasztása streptococcus pneumoniae poliszacharidtól PH manipulációjával

Info

Publication number
HUE050049T2
HUE050049T2 HUE18199835A HUE18199835A HUE050049T2 HU E050049 T2 HUE050049 T2 HU E050049T2 HU E18199835 A HUE18199835 A HU E18199835A HU E18199835 A HUE18199835 A HU E18199835A HU E050049 T2 HUE050049 T2 HU E050049T2
Authority
HU
Hungary
Prior art keywords
contaminants
manipulation
separation
streptococcus pneumoniae
pneumoniae polysaccharide
Prior art date
Application number
HUE18199835A
Other languages
English (en)
Inventor
Brian Bahler
Tsu-Shun Lee
Jason Arnold Lotvin
Mark Edward Ruppen
Pamela Sue Fink Charbonneau
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36660782&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE050049(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of HUE050049T2 publication Critical patent/HUE050049T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/085Staphylococcus
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0003General processes for their isolation or fractionation, e.g. purification or extraction from biomass
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06Lysis of microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Sustainable Development (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HUE18199835A 2005-04-08 2006-03-31 Szennyezõanyagok elválasztása streptococcus pneumoniae poliszacharidtól PH manipulációjával HUE050049T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66954605P 2005-04-08 2005-04-08

Publications (1)

Publication Number Publication Date
HUE050049T2 true HUE050049T2 (hu) 2020-11-30

Family

ID=36660782

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE18199835A HUE050049T2 (hu) 2005-04-08 2006-03-31 Szennyezõanyagok elválasztása streptococcus pneumoniae poliszacharidtól PH manipulációjával

Country Status (20)

Country Link
US (1) US7718791B2 (hu)
EP (2) EP3466982B1 (hu)
JP (1) JP5049264B2 (hu)
KR (1) KR101317256B1 (hu)
CN (1) CN101155833B (hu)
AR (1) AR053843A1 (hu)
AU (1) AU2006234984B2 (hu)
BR (1) BRPI0607026B1 (hu)
CA (1) CA2604362C (hu)
DK (2) DK1866342T3 (hu)
ES (2) ES2808126T3 (hu)
HU (1) HUE050049T2 (hu)
IL (1) IL186366A (hu)
MX (1) MX2007012337A (hu)
NZ (1) NZ562719A (hu)
PL (2) PL3466982T3 (hu)
PT (2) PT3466982T (hu)
SI (2) SI3466982T1 (hu)
TR (1) TR201820018T4 (hu)
WO (1) WO2006110352A2 (hu)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR122019021950B8 (pt) * 2006-10-10 2021-07-27 Wyeth Corp métodos para a redução ou remoção de impurezas protéicas de um lisado ou centrado celular de streptococcus pneumoniae compreendendo polissacarídeos sorotipo 3
AU2013201631C1 (en) * 2006-10-10 2015-06-04 Wyeth Llc Purification of Streptococcus pneumoniae type 3 polysaccharides
ES2922132T3 (es) 2007-03-23 2022-09-08 Wyeth Llc Procedimiento abreviado de purificación para la producción de polisacáridos capsulares de Streptococcus pneumoniae
GB0822634D0 (en) 2008-12-11 2009-01-21 Novartis Ag Meningitis vaccines
BRPI0923165A8 (pt) * 2008-12-18 2017-09-12 Wyeth Llc método para a produção de uma solução contendo polissacarídeos capsulares de streptococcus pneumoniae isolados de alto peso molecular, bem como solução contendo os referidos polissacarídeos
PT2379734T (pt) * 2008-12-18 2018-04-27 Wyeth Llc Método para o controlo da massa molecular do polissacárido do serotipo 19a de streptococcus pneumoniae
CA2756533A1 (en) 2009-03-24 2010-09-30 Novartis Ag Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates
HUE049695T2 (hu) 2009-03-24 2020-10-28 Glaxosmithkline Biologicals Sa Adjuváló H meningococcus faktort kötõ fehérje
WO2010125480A1 (en) 2009-04-30 2010-11-04 Coley Pharmaceutical Group, Inc. Pneumococcal vaccine and uses thereof
WO2011145108A2 (en) * 2010-05-15 2011-11-24 Serum Institute Of India Ltd. Purification of capsular polysaccharides
US10478483B2 (en) 2010-06-25 2019-11-19 Glaxosmithkline Biologicals Sa Combinations of meningococcal factor H binding proteins
CN102093963B (zh) * 2010-11-26 2012-11-14 兰州生物制品研究所有限责任公司 富含磷壁酸的肺炎链球菌的培养方法
CN102094053B (zh) * 2010-11-26 2013-01-16 兰州生物制品研究所有限责任公司 肺炎链球菌c多糖的纯化方法
JP6191082B2 (ja) 2011-03-02 2017-09-06 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム より低用量の抗原および/またはアジュバントを有する混合ワクチン
BR112014016223A8 (pt) 2011-12-29 2017-07-04 Novartis Ag combinações adjuvantes de proteínas de ligação de fator h meningocócico
WO2013131983A1 (en) 2012-03-07 2013-09-12 Novartis Ag Adjuvanted formulations of streptococcus pneumoniae antigens
US20150125486A1 (en) 2012-03-08 2015-05-07 Novartis Ag Adjuvanted formulations of pediatric antigens
CN102660601B (zh) * 2012-04-17 2015-10-28 江苏康泰生物医学技术有限公司 快速纯化细菌荚膜多糖的方法
CN102660603B (zh) * 2012-04-17 2015-03-25 江苏康泰生物医学技术有限公司 一种快速纯化细菌荚膜多糖的方法
CN102660602B (zh) * 2012-04-17 2015-03-25 江苏康泰生物医学技术有限公司 快速纯化细菌荚膜多糖的方法
MX2015002717A (es) 2012-09-06 2015-05-15 Novartis Ag Vacunas combinadas con meningococo del serogrupo b y toxoides de difteria/tetanos/tosferina.
AU2013313794B2 (en) 2012-09-07 2016-10-20 Sk Bioscience Co., Ltd. Production method for capsular polysaccharide having pneumococcal serotype
CA2894260A1 (en) 2012-12-18 2014-06-26 Glaxosmithkline Biologicals S.A. Conjugates for protecting against diphtheria and/or tetanus
PL3096783T3 (pl) 2014-01-21 2021-12-13 Pfizer Inc. Polisacharydy otoczkowe streptococcus pneumoniae i ich koniugaty
MX371453B (es) 2014-01-21 2020-01-29 Pfizer Polisacaridos capsulares de streptococcus pneumoniae y conjugados de los mismos.
US11160855B2 (en) 2014-01-21 2021-11-02 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
RU2771293C2 (ru) 2014-01-21 2022-04-29 Пфайзер Инк. Иммуногенные композиции, содержащие конъюгированные капсульные сахаридные антигены, и их применение
MX2017009308A (es) 2015-01-15 2017-11-08 Pfizer Composiciones inmunogenicas para usar en vacunas neumococicas.
EP3292146A1 (en) 2015-05-04 2018-03-14 Pfizer Inc Group b streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof
TWI720448B (zh) 2015-07-21 2021-03-01 美商輝瑞股份有限公司 包含經共軛之莢膜糖抗原的致免疫性組成物、包含該致免疫性組成物之套組及彼等之用途
WO2017085586A1 (en) 2015-11-20 2017-05-26 Pfizer Inc. Immunogenic compositions for use in pneumococcal vaccines
EP3493837B1 (en) 2016-08-05 2022-08-31 Sanofi Pasteur, Inc. Multivalent pneumococcal polysaccharide-protein conjugate composition
SG11201900789VA (en) 2016-08-05 2019-02-27 Sanofi Pasteur Inc Multivalent pneumococcal polysaccharide-protein conjugate composition
US10751402B2 (en) 2016-11-09 2020-08-25 Pfizer Inc. Immunogenic compositions and uses thereof
IL317054A (en) 2016-12-30 2025-01-01 Vaxcyte Inc Polypeptide-antigen conjugates with unnatural amino acids
US11951165B2 (en) 2016-12-30 2024-04-09 Vaxcyte, Inc. Conjugated vaccine carrier proteins
BR112019014833A2 (pt) 2017-01-20 2020-04-14 Pfizer composições imunogênicas para uso em vacinas pneumococais
CN116870144A (zh) 2017-01-31 2023-10-13 默沙东有限责任公司 制备多糖-蛋白缀合物的方法
CN107043431B (zh) * 2017-02-23 2020-06-30 上海瑞宙生物科技有限公司 细菌性荚膜多糖的纯化方法
MX2019009867A (es) 2017-02-24 2019-10-02 Merck Sharp & Dohme Inmunogenicidad mejorada de conjugados de polisacarido-proteina de streptococcus pneumoniae.
BR112020004502A8 (pt) 2017-09-07 2022-11-01 Merck Sharp & Dohme Polissacarídeos pneumocócicos e uso dos mesmos em conjugados imunogênicos polissacarídeo-proteína carreadora
BR112020004471A8 (pt) 2017-09-07 2022-11-01 Merck Sharp & Dohme Polissacarídeos pneumocócicos e uso dos mesmos em conjugados imunogênicos polissacarídeo-proteína carreadora
MX2020005779A (es) 2017-12-06 2020-10-28 Merck Sharp & Dohme Composiciones que comprenden conjugados de polisacarido de streptococcus pneumoniae con proteina y metodos de uso de estos.
WO2019212844A1 (en) 2018-04-30 2019-11-07 Merck Sharp & Dohme Corp. Methods for providing a homogenous solution of lyophilized mutant diptheria toxin in dimethylsulfoxide
US20210252125A1 (en) 2018-04-30 2021-08-19 Merck Sharp & Dohme Corp. Methods for producing streptococcus pneumoniae capsular polysaccharide carrier protein conjugates
KR20210005161A (ko) 2018-04-30 2021-01-13 머크 샤프 앤드 돔 코포레이션 리오스피어로부터 스트렙토코쿠스 뉴모니아에 피막 폴리사카라이드 담체 단백질 접합체를 제조하는 방법
WO2020010016A1 (en) 2018-07-04 2020-01-09 Sutrovax, Inc. Self-adjuvanted immunogenic conjugates
WO2020010000A1 (en) 2018-07-04 2020-01-09 Sutrovax, Inc. Improved methods for the preparation of immunogenic conjugates
EP3817775B1 (en) 2018-07-04 2024-09-04 Vaxcyte, Inc. Improvements in immunogenic conjugates
WO2020121159A1 (en) 2018-12-12 2020-06-18 Pfizer Inc. Immunogenic multiple hetero-antigen polysaccharide-protein conjugates and uses thereof
KR20240169145A (ko) 2018-12-19 2024-12-02 머크 샤프 앤드 돔 엘엘씨 스트렙토코쿠스 뉴모니아에 폴리사카라이드-단백질 접합체를 포함하는 조성물 및 그의 사용 방법
JP7239509B6 (ja) * 2019-02-22 2023-03-28 ファイザー・インク 細菌多糖類を精製するための方法
EP3952906A1 (en) 2019-04-10 2022-02-16 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens, kits comprising the same and uses thereof
JP2022542316A (ja) 2019-07-31 2022-09-30 サノフィ パスツール インコーポレイテッド 多価肺炎球菌多糖体-タンパク質コンジュゲート組成物およびその使用方法
US20210070890A1 (en) * 2019-09-06 2021-03-11 Serum Institute Of India Private Limited Method for obtaining purified bacterial polysaccharides
WO2021229604A1 (en) * 2020-05-14 2021-11-18 Serum Institute Of India Private Limited Methods for simultaneous fragmentation and purification of bacterial polysaccharides
CA3192786A1 (en) 2020-08-26 2022-03-03 Pfizer Inc. Group b streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof
GB202016165D0 (en) 2020-10-12 2020-11-25 Optivalent Ltd Vaccine
CA3200602A1 (en) 2020-11-04 2022-05-12 Pfizer Inc. Immunogenic compositions for use in pneumococcal vaccines
US20230405137A1 (en) 2020-11-10 2023-12-21 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
EP4333879A1 (en) 2021-05-03 2024-03-13 Pfizer Inc. Vaccination against bacterial and betacoronavirus infections
WO2022234416A1 (en) 2021-05-03 2022-11-10 Pfizer Inc. Vaccination against pneumoccocal and covid-19 infections
JP2024521847A (ja) 2021-05-28 2024-06-04 ファイザー・インク コンジュゲート化莢膜糖抗原を含む免疫原性組成物およびその使用
PH12023553205A1 (en) 2021-05-28 2024-02-19 Pfizer Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
EP4463186A1 (en) 2022-01-13 2024-11-20 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
GB2614916A (en) 2022-01-25 2023-07-26 Optivalent Ltd Intradermal vaccine complement
CN116693706B (zh) * 2022-02-24 2024-10-11 成都生物制品研究所有限责任公司 一种肺炎链球菌荚膜多糖的纯化方法
WO2023161817A1 (en) 2022-02-25 2023-08-31 Pfizer Inc. Methods for incorporating azido groups in bacterial capsular polysaccharides
CN114853917A (zh) * 2022-04-22 2022-08-05 兰州生物制品研究所有限责任公司 制备肺炎球菌荚膜多糖和肺炎球菌疫苗的方法
WO2024084397A1 (en) 2022-10-19 2024-04-25 Pfizer Inc. Vaccination against pneumoccocal and covid-19 infections
WO2024110827A1 (en) 2022-11-21 2024-05-30 Pfizer Inc. Methods for preparing conjugated capsular saccharide antigens and uses thereof
US20240181028A1 (en) 2022-11-22 2024-06-06 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
WO2024116096A1 (en) 2022-12-01 2024-06-06 Pfizer Inc. Pneumococcal conjugate vaccine formulations
WO2024166008A1 (en) 2023-02-10 2024-08-15 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
WO2024201324A2 (en) 2023-03-30 2024-10-03 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
WO2024214016A1 (en) 2023-04-14 2024-10-17 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
WO2024224266A1 (en) 2023-04-24 2024-10-31 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
WO2024241172A2 (en) 2023-05-19 2024-11-28 Glaxosmithkline Biologicals Sa Methods for eliciting an immune response to respiratory syncycial virus and streptococcus pneumoniae infection
WO2025057078A1 (en) 2023-09-14 2025-03-20 Pfizer Inc. Adjuvanted immunogenic compositions comprising conjugated pneumococcal capsular saccharide antigens and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1115210A (en) * 1977-11-28 1981-12-29 Dennis J. Carlo Pneumococcal vaccine
US4242501A (en) * 1979-08-08 1980-12-30 American Cyanamid Company Purification of pneumococcal capsular polysaccharides
FR2495939B1 (fr) 1980-12-11 1985-10-11 Merieux Inst Procede de purification de polyosides de streptococcus pneumoniae et vaccin a base de polyosides ainsi purifies
BE889979A (fr) * 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation
US5714354A (en) * 1995-06-06 1998-02-03 American Home Products Corporation Alcohol-free pneumococcal polysaccharide purification process
EP1144640A3 (en) * 1998-07-27 2001-11-28 Microbial Technics Limited Nucleic acids and proteins from streptococcus pneumoniae
DK1268844T3 (da) * 2000-03-16 2009-11-16 Philadelphia Children Hospital Modulering af fremstilling af pneumococcus kapselformigt polysaccharid

Also Published As

Publication number Publication date
ES2808126T3 (es) 2021-02-25
PT3466982T (pt) 2020-07-24
CN101155833A (zh) 2008-04-02
IL186366A (en) 2012-10-31
JP5049264B2 (ja) 2012-10-17
AR053843A1 (es) 2007-05-23
AU2006234984B2 (en) 2011-10-13
BRPI0607026B1 (pt) 2022-02-15
NZ562719A (en) 2008-12-24
PT1866342T (pt) 2019-01-30
PL1866342T3 (pl) 2019-04-30
IL186366A0 (en) 2008-01-20
KR101317256B1 (ko) 2013-10-14
TR201820018T4 (tr) 2019-01-21
US20060228381A1 (en) 2006-10-12
KR20080005414A (ko) 2008-01-11
WO2006110352A3 (en) 2007-03-29
CN101155833B (zh) 2011-04-20
ES2707202T3 (es) 2019-04-02
WO2006110352A2 (en) 2006-10-19
DK3466982T3 (da) 2020-08-03
PL3466982T3 (pl) 2020-11-02
EP3466982A1 (en) 2019-04-10
SI1866342T1 (sl) 2019-02-28
SI3466982T1 (sl) 2020-08-31
DK1866342T3 (en) 2019-01-28
BRPI0607026A2 (pt) 2009-07-28
EP3466982B1 (en) 2020-06-17
CA2604362A1 (en) 2006-10-19
US7718791B2 (en) 2010-05-18
EP1866342B1 (en) 2018-11-21
JP2008535490A (ja) 2008-09-04
AU2006234984A1 (en) 2006-10-19
MX2007012337A (es) 2007-11-21
CA2604362C (en) 2013-11-12
EP1866342A2 (en) 2007-12-19

Similar Documents

Publication Publication Date Title
IL186366A0 (en) SEPARATION OF CONTAMINANTS FROM STREPTOCOCCUS PNEUMONIAE POLYSACCHARIDE BY pH MANIPULATION
IL184980A0 (en) Purification of streptococcal capsular polysaccharide
GB2425620B (en) Production system
TWI368611B (en) Improving product recovery from simulated-moving-bed adsorption
JP2010505963A5 (ja) 肺炎連鎖球菌3型多糖体の精製
ZA200803318B (en) Separation process
GB2429993B (en) Production system
ZA200808372B (en) Antibody purification
EP1961239A4 (en) SELECTIVE THROTTLE OF PRESENCE UPDATES
EP1885410A4 (en) SWIVEL CATHETERISM SYSTEM FOR ADVANCING
EP1872189A4 (en) GENERIC CLASSIFICATION SYSTEM
HK1109466A1 (en) Automation system
ZA200709326B (en) Dairy production information system
GB0503942D0 (en) Purification process
GB0624555D0 (en) Filtering signals
EP1971202A4 (en) SERUM PRODUCTION SYSTEM
GB2426419B (en) Signal processing systems
PL2074221T3 (pl) Ulepszone sposoby oddzielania polisacharydów Streptococcus pneumoniae typu 3
GB2442361B (en) Signal processing systems
GB0505247D0 (en) Teaching aid
GB0500855D0 (en) Cadesorb PH buffer
AU2005906908A0 (en) Mineral separating means
AU308097S (en) Teaspoon
ZA201100565B (en) Antibody purification
GB0523058D0 (en) Separation system