HRP20040090A2 - Arylsulfonyl derivatives with 5-ht6 receptor affinity - Google Patents

Arylsulfonyl derivatives with 5-ht6 receptor affinity

Info

Publication number: HRP20040090A2
Authority: HR; Croatia
Prior art keywords: sub; receptor affinity; arylsulfonyl derivatives; compounds; methods
Prior art date: 2001-08-10

Application number

Other languages

English (en)

Inventor

Jacob Berger

Robin Douglas Clark

Shu-Hai Zhao

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-08-10

Filing date

2002-08-05

Publication date

2004-12-31

2002-08-05 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2004-12-31 Publication of HRP20040090A2 publication Critical patent/HRP20040090A2/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Addiction (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Physical Education & Sports Medicine (AREA)
Hematology (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Nutrition Science (AREA)
Child & Adolescent Psychology (AREA)
Diabetes (AREA)
Orthopedic Medicine & Surgery (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Compositions Of Macromolecular Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Photoreceptors In Electrophotography (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

HRP20040090 2001-08-10 2002-08-05 Arylsulfonyl derivatives with 5-ht6 receptor affinity HRP20040090A2 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US31150401P	2001-08-10	2001-08-10
US38471102P	2002-05-31	2002-05-31
PCT/EP2002/008696 WO2003014097A1 (en)	2001-08-10	2002-08-05	Arylsulfonyl derivatives with 5-ht6 receptor affinity

Publications (1)

Publication Number	Publication Date
HRP20040090A2 true HRP20040090A2 (en)	2004-12-31

Family

ID=26977917

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HRP20040090 HRP20040090A2 (en)	2001-08-10	2002-08-05	Arylsulfonyl derivatives with 5-ht<sub>6</sub> receptor affinity

Country Status (20)

Country	Link
US (1)	US6825202B2 (ru)
EP (1)	EP1423106B1 (ru)
JP (1)	JP4187650B2 (ru)
KR (1)	KR100608417B1 (ru)
CN (1)	CN1254469C (ru)
AT (1)	ATE417838T1 (ru)
AU (1)	AU2002340804B2 (ru)
CA (1)	CA2456250A1 (ru)
CO (1)	CO5550439A2 (ru)
DE (1)	DE60230424D1 (ru)
ES (1)	ES2316619T3 (ru)
HR (1)	HRP20040090A2 (ru)
HU (1)	HUP0401235A2 (ru)
IL (1)	IL159880A0 (ru)
MX (1)	MXPA04001250A (ru)
NO (1)	NO326497B1 (ru)
NZ (1)	NZ530742A (ru)
PL (1)	PL373397A1 (ru)
RU (1)	RU2268884C2 (ru)
WO (1)	WO2003014097A1 (ru)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
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DE60321558D1 (de)	2002-03-27	2008-07-24	Glaxo Group Ltd	Chinolinderivate und deren verwendung als 5-ht6 liganden
TWI285639B (en) *	2002-11-08	2007-08-21	Roche Palo Alto Llc	Substituted benzoxazinones and uses thereof
GB0305575D0 (en) *	2003-03-11	2003-04-16	Glaxo Group Ltd	Novel compounds
TWI289141B (en) *	2003-03-11	2007-11-01	Hoffmann La Roche F. Ag.	Quinolinone derivatives and uses thereof
KR101157272B1 (ko)	2003-07-22	2012-06-15	아레나 파마슈티칼스, 인크.	5?ｈｔ2ａ 세로토닌 수용체의 조절자로서 이와 관련된질환의 예방 및 치료에 유용한 디아릴 및 아릴헤테로아릴우레아 유도체
WO2006062481A1 (en) *	2004-12-09	2006-06-15	Biovitrum Ab	New benzofuran derivatives and their use in the treatment of obesity, type ii diabetes and cns disorders .
DK1831159T3 (da) *	2004-12-21	2010-03-22	Hoffmann La Roche	Tetralin og indanderivater samt anvendelser deraf
EP1695971A1 (en) *	2004-12-30	2006-08-30	Laboratorios Del Dr. Esteve, S.A.	Substituted phenyl-piperazine compounds, their preparation and use in medicaments
US9084742B2 (en)	2007-12-12	2015-07-21	Axovant Sciences Ltd.	Combinations comprising 3-phenylsulfonyl-8-piperazinyl-1yl-Quinoline
US20110021538A1 (en)	2008-04-02	2011-01-27	Arena Pharmaceuticals, Inc.	Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
US9126946B2 (en)	2008-10-28	2015-09-08	Arena Pharmaceuticals, Inc.	Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto
US8183237B2 (en)	2009-04-30	2012-05-22	Abbott Laboratories	Benzenesulfonanilide compounds suitable for treating disorders that respond to modulation of the serotonin 5-HT6 receptor
US8343959B2 (en)	2009-04-30	2013-01-01	Abbott Gmbh & Co. Kg	N-phenyl-(piperazinyl or homopiperazinyl)-benzenesulfonamide or benzenesulfonyl-phenyl-(piperazine or homopiperazine) compounds suitable for treating disorders that respond to modulation of the serotonin 5-HT6 receptor
UA107080C2 (uk) *	2009-04-30	2014-11-25		Сполуки n-феніл(піперазиніл або гомопіперазиніл)бензолсульфонаміду або бензолсульфонілфеніл(піперазину або гомопіперазину), придатні для лікування захворювань, які реагують на модулювання рецептора 5-ht6 серотоніну
WO2012059431A1 (en)	2010-11-01	2012-05-10	Abbott Gmbh & Co. Kg	Benzenesulfonyl or sulfonamide compounds suitable for treating disorders that respond to the modulation of the serotonin 5-ht6 receptor
WO2012059432A1 (en)	2010-11-01	2012-05-10	Abbott Gmbh & Co. Kg	N-phenyl-(homo)piperazinyl-benzenesulfonyl or benzenesulfonamide compounds suitable for treating disorders that respond to the modulation of the 5-ht6 receptor
EP3083588B1 (en)	2013-12-20	2020-12-09	Sunshine Lake Pharma Co., Ltd.	Aromatic heterocyclic compounds and their application in pharmaceuticals
CN105085436B (zh)	2014-04-19	2019-08-16	广东东阳光药业有限公司	磺酰胺类衍生物及其在药物上的应用
WO2016201373A1 (en)	2015-06-12	2016-12-15	Axovant Sciences Ltd.	Diaryl and arylheteroaryl urea derivatives useful for the prophylaxis and treatment of rem sleep behavior disorder
MX391031B (es)	2015-07-15	2025-03-21	Axovant Sciences Gmbh	Derivados de diaril y arilheteroaril urea como moduladores del receptor de serotonina 5-ht2a útiles para la profilaxis y el tratamiento de alucinaciones asociadas con una enfermedad neurodegenerativa.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SU551871A1 (ru) *	1974-03-26	1981-09-07	Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латсср	2-Арилпиперазино-2-фенилинданоны,обладающие психотропными свойствами
DZ2376A1 (fr) *	1996-12-19	2002-12-28	Smithkline Beecham Plc	Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant.
EP0994862B1 (en) *	1997-07-11	2005-06-01	SmithKline Beecham plc	Sulphonamide derivatives being 5-ht6 receptor antagonists and process for their preparation
DE69906397T2 (de)	1998-01-16	2004-02-19	F. Hoffmann-La Roche Ag	Benzosulfonderivate
GB9801392D0 (en) *	1998-01-22	1998-03-18	Smithkline Beecham Plc	Novel compounds
GB9803411D0 (en)	1998-02-18	1998-04-15	Smithkline Beecham Plc	Novel compounds
GB9818916D0 (en)	1998-08-28	1998-10-21	Smithkline Beecham Plc	Use
GB9818914D0 (en)	1998-08-28	1998-10-21	Smithkline Beecham Plc	Use
GB9926302D0 (en)	1999-11-05	2000-01-12	Smithkline Beecham Plc	Novel compounds
PE20020063A1 (es) *	2000-06-20	2002-01-30	Upjohn Co	Bis-arilsulfonas como ligandos del receptor de 5-ht

2002
- 2002-08-05 ES ES02774499T patent/ES2316619T3/es not_active Expired - Lifetime
- 2002-08-05 EP EP02774499A patent/EP1423106B1/en not_active Expired - Lifetime
- 2002-08-05 RU RU2004107261/04A patent/RU2268884C2/ru not_active IP Right Cessation
- 2002-08-05 HU HU0401235A patent/HUP0401235A2/hu unknown
- 2002-08-05 IL IL15988002A patent/IL159880A0/xx unknown
- 2002-08-05 KR KR1020047001985A patent/KR100608417B1/ko not_active Expired - Fee Related
- 2002-08-05 HR HRP20040090 patent/HRP20040090A2/xx not_active Application Discontinuation
- 2002-08-05 AU AU2002340804A patent/AU2002340804B2/en not_active Ceased
- 2002-08-05 CA CA002456250A patent/CA2456250A1/en not_active Abandoned
- 2002-08-05 WO PCT/EP2002/008696 patent/WO2003014097A1/en active Application Filing
- 2002-08-05 MX MXPA04001250A patent/MXPA04001250A/es active IP Right Grant
- 2002-08-05 JP JP2003519047A patent/JP4187650B2/ja not_active Expired - Fee Related
- 2002-08-05 CN CNB02815679XA patent/CN1254469C/zh not_active Expired - Fee Related
- 2002-08-05 PL PL02373397A patent/PL373397A1/xx unknown
- 2002-08-05 AT AT02774499T patent/ATE417838T1/de not_active IP Right Cessation
- 2002-08-05 NZ NZ530742A patent/NZ530742A/en unknown
- 2002-08-05 DE DE60230424T patent/DE60230424D1/de not_active Expired - Lifetime
- 2002-08-09 US US10/215,769 patent/US6825202B2/en not_active Expired - Fee Related
2004
- 2004-02-05 CO CO04009120A patent/CO5550439A2/es not_active Application Discontinuation
- 2004-02-09 NO NO20040589A patent/NO326497B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2456250A1 (en)	2003-02-20
US6825202B2 (en)	2004-11-30
WO2003014097A1 (en)	2003-02-20
RU2268884C2 (ru)	2006-01-27
DE60230424D1 (en)	2009-01-29
IL159880A0 (en)	2004-06-20
EP1423106B1 (en)	2008-12-17
KR20040023738A (ko)	2004-03-18
US20030069254A1 (en)	2003-04-10
HUP0401235A2 (hu)	2004-10-28
ATE417838T1 (de)	2009-01-15
CN1541210A (zh)	2004-10-27
RU2004107261A (ru)	2005-09-10
HK1070054A1 (en)	2005-06-10
ES2316619T3 (es)	2009-04-16
AU2002340804B2 (en)	2008-04-03
JP2005502649A (ja)	2005-01-27
JP4187650B2 (ja)	2008-11-26
EP1423106A1 (en)	2004-06-02
NZ530742A (en)	2007-07-27
NO326497B1 (no)	2008-12-15
NO20040589L (no)	2004-03-19
KR100608417B1 (ko)	2006-08-02
CN1254469C (zh)	2006-05-03
PL373397A1 (en)	2005-08-22
CO5550439A2 (es)	2005-08-31
MXPA04001250A (es)	2004-05-27

Publication	Publication Date	Title
HRP20040090A2 (en)	2004-12-31	Arylsulfonyl derivatives with 5-ht<sub>6</sub> receptor affinity
MXPA03011638A (es)	2004-04-02	Nuevos derivados de 4-piperazinil indol con afinidad por el receptor 5-ht6.
BG108420A (en)	2005-02-28	New indole derivatives with 5-ht6 receptor affinity
AP1739A (en)	2007-05-09	Azaindoles
PL367618A1 (en)	2005-03-07	5-halo-tryptamine derivatives used as ligands of the 5-ht6 and/or 5-ht 7 serotonin receptors
MXPA02012033A (es)	2003-04-25	Derivados de 2-aminocarbonil-9h-purina.
PL361361A1 (en)	2004-10-04	Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists
MXPA04007414A (es)	2004-10-11	Indoles sustituidos como agonistas alfa-1.
DE60208568D1 (de)	2006-03-30	Prostaglandinanaloga als ep4-rezeptoragonisten
SE9904508D0 (sv)	1999-12-09	New compounds
SE0302760D0 (sv)	2003-10-20	New compounds
PL361282A1 (en)	2004-10-04	Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists
WO2005060959A8 (en)	2006-01-12	Pyrazole derivatives and use thereof as orexin receptor antagonists
PL374019A1 (en)	2005-09-19	Benzoxazine derivatives as 5-ht6 modulators and uses thereof
SE0102055D0 (sv)	2001-06-08	New Compounds
MXPA04005426A (es)	2004-10-11	Derivados de pirazol de anillos fuisionados.
MXPA04005313A (es)	2004-09-13	Derivados de aminotetralin como antagonistas del receptor muscarinico.
MXPA04005076A (es)	2004-08-19	Derivados de 4-piperidinil alquilamina como antagonistas del receptor muscarinico.
CA2490115A1 (en)	2003-12-31	Arylalkyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
PL1660484T3 (pl)	2009-02-27	Metyloindole i metylopirolopirydyny jako agoniści receptora adrenergicznego α-1
CA2490002A1 (en)	2003-12-31	Novel tetracyclic arylcarbonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
SE0301371D0 (sv)	2003-05-09	New Compounds
EE05300B1 (et)	2010-06-15	Akrloldistamtsiini derivaati sisaldav farmatseutiline kompositsioon, derivaadi kasutamine tuumorivastase ravimi valmistamiseks ning kombineeritud ravimpreparaat
AU2001295837A1 (en)	2002-05-15	Aminoalkylpyrrolidine serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their synthesis
GB0114699D0 (en)	2001-08-08	Organic compounds

Legal Events

Date	Code	Title	Description
2004-12-31	A1OB	Publication of a patent application
2005-06-16	ARAI	Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
2008-07-31	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20080731 Year of fee payment: 7
2009-05-29	OBST	Application withdrawn

HRP20040090A2 - Arylsulfonyl derivatives with 5-ht<sub>6</sub> receptor affinity - Google Patents