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HK1258528A1 - 幹細胞移植方法和幹細胞移植組合物 - Google Patents

幹細胞移植方法和幹細胞移植組合物

Info

Publication number
HK1258528A1
HK1258528A1 HK19100883.9A HK19100883A HK1258528A1 HK 1258528 A1 HK1258528 A1 HK 1258528A1 HK 19100883 A HK19100883 A HK 19100883A HK 1258528 A1 HK1258528 A1 HK 1258528A1
Authority
HK
Hong Kong
Prior art keywords
compositions
methods
stem cell
cell transplantation
transplantation
Prior art date
Application number
HK19100883.9A
Other languages
English (en)
Inventor
Paul William Finnegal
Claude Geoffrey Davis
Michael Daniel Ginsberg
Daniel Joseph Nolan
Original Assignee
Angiocrine Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angiocrine Bioscience Inc filed Critical Angiocrine Bioscience Inc
Publication of HK1258528A1 publication Critical patent/HK1258528A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/44Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/28Vascular endothelial cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Developmental Biology & Embryology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
HK19100883.9A 2015-07-20 2019-01-17 幹細胞移植方法和幹細胞移植組合物 HK1258528A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562194460P 2015-07-20 2015-07-20
PCT/US2016/042872 WO2017015245A1 (en) 2015-07-20 2016-07-19 Methods and compositions for stem cell transplantation

Publications (1)

Publication Number Publication Date
HK1258528A1 true HK1258528A1 (zh) 2019-11-15

Family

ID=57834594

Family Applications (1)

Application Number Title Priority Date Filing Date
HK19100883.9A HK1258528A1 (zh) 2015-07-20 2019-01-17 幹細胞移植方法和幹細胞移植組合物

Country Status (14)

Country Link
US (2) US20180214488A1 (zh)
EP (2) EP3325612B1 (zh)
JP (2) JP7089282B2 (zh)
KR (1) KR20180048617A (zh)
CN (1) CN108350419A (zh)
AU (2) AU2016297523B2 (zh)
CA (1) CA2993014A1 (zh)
DK (1) DK3325612T3 (zh)
ES (1) ES2939635T3 (zh)
FI (1) FI3325612T3 (zh)
HK (1) HK1258528A1 (zh)
RU (1) RU2757818C2 (zh)
SG (1) SG10201913752PA (zh)
WO (1) WO2017015245A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108291196B (zh) * 2015-07-20 2021-08-27 安吉克莱茵生物科学有限公司 表达ets转录因子的工程化的内皮细胞
US12011488B2 (en) 2016-03-23 2024-06-18 The Regents Of The University Of California Methods of treating mitochondrial disorders
WO2017165167A1 (en) 2016-03-23 2017-09-28 The Regents Of The University Of California Methods of treating mitochondrial disorders
CN110121555B (zh) 2016-09-13 2023-10-20 安吉克莱茵生物科学有限公司 包含工程化内皮细胞的血脑屏障
WO2018170239A1 (en) * 2017-03-15 2018-09-20 The Regents Of The University Of California Methods of treating lysosomal disorders
CN106929469B (zh) * 2017-04-25 2020-08-07 徐子雁 间充质干细胞分化为表皮细胞的方法及试剂盒
WO2019183508A1 (en) * 2018-03-23 2019-09-26 The Children's Medical Center Corporation Endothelial cell factors and methods thereof
AU2021297353A1 (en) * 2020-06-25 2023-02-02 Angiocrine Bioscience, Inc. Endothelial cells for mitigation of chemotherapy-induced toxicity

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0317156B2 (en) 1987-11-09 1997-11-12 Becton, Dickinson and Company Method for analysis of hematopoietic cells in a sample
US5061620A (en) 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US5840580A (en) 1990-05-01 1998-11-24 Becton Dickinson And Company Phenotypic characterization of the hematopoietic stem cell
US6326198B1 (en) 1990-06-14 2001-12-04 Regents Of The University Of Michigan Methods and compositions for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells
DE4322570C1 (de) * 1993-07-07 1994-06-16 Gsf Forschungszentrum Umwelt Stromale Zellinien aus menschlichem Knochenmark
US5599703A (en) * 1993-10-28 1997-02-04 The United States Of America As Represented By The Secretary Of The Navy In vitro amplification/expansion of CD34+ stem and progenitor cells
US5925567A (en) 1995-05-19 1999-07-20 T. Breeders, Inc. Selective expansion of target cell populations
US6335195B1 (en) 1997-01-28 2002-01-01 Maret Corporation Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation
US6100086A (en) * 1997-04-14 2000-08-08 Genzyme Corporation Transgene expression systems
CA2396576A1 (en) 2000-01-18 2001-07-26 Tannishtha Reya Expansion of stem and progenitor cells by beta-catenin
AU2002225959A1 (en) * 2000-11-09 2002-05-21 Mayo Foundation For Medical Education And Research Absolute lymphocyte recovery and cancer survival
WO2003038048A2 (en) * 2001-10-30 2003-05-08 The United States Of America As Represented By The Secretary Of The Navy Ex-vivo rescue of transplantable hematopoietic stem cells following myeloablative injury
US7635477B2 (en) * 2002-07-25 2009-12-22 The General Hospital Corporation Parathyroid hormone receptor activation and stem and progenitor cell expansion
US8465732B2 (en) * 2007-01-19 2013-06-18 Cornell Research Foundation, Inc. Endothelial cells expressing adenovirus E4ORF1 and methods of use thereof
JP5897002B2 (ja) 2010-07-07 2016-04-13 セルラー ダイナミクス インターナショナル, インコーポレイテッド プログラミングによる内皮細胞の産生
CN103167876B (zh) * 2010-08-12 2016-08-31 菲特治疗公司 改进的造血干细胞和祖细胞疗法
CN102643784B (zh) * 2012-03-29 2016-05-25 中国人民解放军第四军医大学 一种造血干/祖细胞的体外扩增体系
CA2874764C (en) * 2012-05-30 2022-11-01 Cornell University Generation of functional and durable endothelial cells from human amniotic fluid-derived cells
EP2946007B1 (en) * 2013-01-15 2019-04-10 Cornell University Reprogramming of human endothelium into hematopoietic multi-lineage progenitors by defined factors
JP2015109833A (ja) 2013-11-08 2015-06-18 学校法人慶應義塾 線維芽細胞から血管内皮細胞を製造する方法
US11111472B2 (en) * 2014-10-31 2021-09-07 Massachusetts Institute Of Technology Delivery of biomolecules to immune cells

Also Published As

Publication number Publication date
CN108350419A (zh) 2018-07-31
AU2016297523A1 (en) 2018-02-22
AU2016297523B2 (en) 2022-07-28
RU2757818C2 (ru) 2021-10-21
JP7089282B2 (ja) 2022-06-22
WO2017015245A1 (en) 2017-01-26
RU2018105988A3 (zh) 2020-01-21
JP2022121446A (ja) 2022-08-19
KR20180048617A (ko) 2018-05-10
EP3325612A1 (en) 2018-05-30
JP7473984B2 (ja) 2024-04-24
EP3325612B1 (en) 2022-12-14
US20180214488A1 (en) 2018-08-02
DK3325612T3 (da) 2023-03-06
FI3325612T3 (fi) 2023-03-20
CA2993014A1 (en) 2017-01-26
EP4202036A1 (en) 2023-06-28
WO2017015245A8 (en) 2022-11-03
EP3325612A4 (en) 2018-12-26
ES2939635T3 (es) 2023-04-25
AU2022204899A1 (en) 2022-07-28
SG10201913752PA (en) 2020-03-30
US20230414671A1 (en) 2023-12-28
JP2018521074A (ja) 2018-08-02
RU2018105988A (ru) 2019-08-20

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