HK1257892A1

HK1257892A1 - Fine dust-proof composition comprising negatively charged material

Info

Publication number: HK1257892A1
Application number: HK19100253.1A
Authority: HK
Inventors: 李承桓; 李炫锡; 崔庚浩; 李炫錫
Original assignee: 株式会社爱茉莉太平洋; 株式會社愛茉莉太平洋
Priority date: 2015-10-30
Filing date: 2016-10-28
Publication date: 2019-11-01
Also published as: KR20170050390A; WO2017074125A1; CN108430446A

Abstract

Disclosed in the present specification is a dust-proof composition comprising, a negatively charged material as an active ingredient. Particularly, a polymer or an inorganic material contained, as the active ingredient, in the dust-proof composition have similar zeta potential to dust such that the dust attached to the skin by electrostatic force can be minimized, and the dust can be readily removed from the skin even if the dust is temporarily attached to the skin. Specifically, the fine dust is prevented from penetrating the skin so as to minimize skin inflammation and the accumulation of heavy metals, and thus the dust-proof composition is beneficial for the skin health.

Description

Composition for dust control containing negatively charged substance

Technical Field

The present specification discloses novel compositions for dust control.

Background

When dust is deposited in the body, the immunity of the human body is lowered, and various diseases such as heart diseases or respiratory diseases may be induced. Even resulting in bronchoconstriction, increased prevalence of asthma or pulmonary disease, and early mortality upon prolonged inhalation.

The skin, the outermost part of the human body in direct contact with dust, acts as a barrier between the organisms and the environment, and its barrier function is reduced when it is often exposed directly to pollution. In particular, since the fine dust is 20 times smaller than pores, the fine dust easily enters the skin. It is known that air pollutants such as fine dust actually have a serious influence on skin health. Early aging, lack of moisture, increase of fine lines and wrinkles in a short period of time, and in a long period of time, the skin loses its function of protecting the body from environmental factors due to unrecoverable skin damage, thereby causing serious diseases such as skin cancer.

Therefore, research into cosmetics for preventing dust, which is a harmful substance harmful to the skin and sometimes fatal to the human body, from adhering to the skin is required.

Disclosure of Invention

In one aspect, the present invention is directed to preventing dust from adhering to the skin.

On the other hand, the present invention aims to easily remove dust adhering to the skin.

In another aspect, the present invention aims to minimize skin intrusion of fine dust.

On the other hand, the present invention aims to prevent or minimize the contamination of the skin by the fine dusts.

In one aspect, the present invention provides a composition for dust control, comprising a negatively charged substance having a ZETA potential value of-2 mV or less in an aqueous solution having a pH of 7 as an active ingredient, wherein the negatively charged substance is a polymer or an inorganic substance.

In one aspect, the composition for preventing dust of the present invention can minimize adhesion of dust, particularly fine dust, to the skin. Specifically, since the negatively charged substance contained as an active ingredient in the composition for preventing dust has a ZETA potential of a negative charge similar to that of dust, it is possible to minimize the adhesion of dust to the skin based on electrostatic force, and to easily remove dust from the skin even if dust is temporarily adhered to the skin. In particular, the invasion of fine dust into the skin is prevented, and inflammation of the skin and accumulation of heavy metals caused thereby are minimized, thereby benefiting skin health.

Drawings

FIG. 1 is a graph showing the results of carbon black adsorption tests in artificial leather treated with a composition comprising a negatively charged post-supplementation substance (1: control, 2: PMAA-containing sodium salt (MW 75100), 3: PMAA-containing sodium salt (MW 18500), 4: PMAA-containing sodium salt (MW 7750), 5: phosphoipon-containing 100, 6: MPC-TiO-containing₂7: PMAA-sodium containing solution, 8: phospholipon90, 9: containing titanium oxide (TiO)₂(Titanium Oxide)), 10: containing PMAA-TiO₂11: control, 12: zinc Oxide (ZnO, (Zinc Oxide)), 13: containing aluminum oxide (Al)₂O₃) 14: containing chitosan).

FIG. 2 is a graph showing the results of a carbon black adsorption test in artificial hair treated with a composition comprising a negatively charged post-supplementation substance (blank: control, sample 1: containing PMAA-sodium salt (mw ═ 75100), sample 2: containing PMAA-sodium salt (mw ═ 18500), sample 3: containing phospholipon100, sample 4: containing titanium dioxide surface-treated with MPC (MPC-TiO)₂) Sample 5: PMAA-sodium, sample 6: containing titanium dioxide surface-treated with PMAA (PMAA-TiO)₂))。

Detailed Description

The dust prevention in the present specification means to prevent or minimize the adhesion of dust to the skin, or to prevent or minimize the invasion of dust temporarily adhered to the skin by removing it from the skin. That is, when the composition for preventing dust of the present specification is applied to the skin, it is possible to minimize the adhesion of dust to the skin, and even if dust adheres to the skin, it can be easily removed by physical force such as wind.

In the specification, dust is a general term for fine particles mixed in the air, and generally means a suspended substance having a particle diameter of 0.1 μm to 10 mm. In particular, the fine dust is called when the particle size is 10 μm or less, and the ultrafine dust is called when the particle size is 0.1 μm or less. The particle size may mean the average particle diameter of the fine dust. Dust is a substance containing substances from nature such as sand, soil and pollen, or substances from industrial processes such as carbon, carbon combustion products, metal salts and heavy metals. The dust may be present in the form of smoke (fume), fog (mist), smoke, steam or fog. Generally, the value of the ZETA potential of dust, particularly fine dust, is negative.

In one aspect, the present invention is a composition for dust control comprising, as an active ingredient, a negatively charged substance having a ZETA potential value of-2 mV or less in an aqueous solution having a pH of 7, wherein the negatively charged substance is a polymer or an inorganic substance. In the present specification, a negatively charged substance means a substance having a negative value of the ZETA potential (ZETA potential) value. The ZETA potential value can be determined by generally known methods.

The value of the ZETA potential of the negatively charged substance may be not more than-2 mV, not more than-3 mV, not more than-10 mV, not more than-20 mV, not more than-30 mV, not more than-40 mV, not more than-50 mV, not more than-60 mV, or not more than-70 mV, but is not limited thereto.

In the aspect as described above, the above-mentioned negatively charged substance may have a ZETA potential value of-50 mV to-10 mV in an aqueous solution of pH 7. The above-mentioned ZETA potential value may be, but is not limited to, from-50 mV to-10 mV, -45mV to-10 mV, -40mV to-10 mV, -35mV to-10 mV, -30mV to-10 mV, -25mV to-10 mV, -50mV to-15 mV, -50 to-20 mV, -50 to-25 mV, -50 to-30 mV, -50 to-35 mV, or-50 to-40 mV. Particularly, the above-mentioned polymer or inorganic substance has a ZETA potential value in the range of-45 mV to-10 mV, and the dust-proofing effect is most excellent. Since the fine dust has a negative ZETA potential, the skin adhesion can be minimized by the electrostatic repulsion with the negatively charged substance in the composition for dust prevention.

In the aspect described above, the polymer may be phospholipid (phospholipid) or poly (methacrylate), but is not limited thereto.

The inorganic substance may be silicon dioxide (SiO)₂) Or titanium dioxide (TiO)₂) However, the present invention is not limited thereto.

The phospholipid may be selected from phosphatidylglycerol (phosphatidylglycerol), phosphatidylethanolamine (phosphatidylethanolamine), phosphatidylserine (phosphatidylserine), polyethylene glycol phospholipid (polyethylene glycol phospholipid), sphingomyelin (sphingomyelin), and phosphatidylcholine (phosphatidylethanolamine), but is not limited thereto.

The phosphatidylcholine may be hydrogenated phosphatidylcholine (hydrogenated phosphatidylcholine).

In one embodiment, the phosphatidylcholine is Poissolve's trademarkSpraying in a slosh slopeSpraying in a slosh slopeSpraying in a slosh slopeSpraying in a slosh slopeSpraying in a slosh slopeSpraying in a slosh slopeSpraying in a slosh slopeOr spraying in a sloping slopeThe substance of (1). These materials are available from sigma aldrich.

In addition, the above poly (methacrylate) may contain poly (methacrylic acid) sodium salt (poly (methacrylic acid)).

In one embodiment, the poly (methacrylic acid) sodium Salt (poly (methacryl acid) sodium Salt) may be poly (methacrylic acid) -sodium Salt (PMAA-Na Salt) (MW 75100), poly (methacrylic acid) -sodium Salt (PMAA-Na Salt) (MW 18500), poly (methacrylic acid) -sodium Salt (PMAA-NaSalt) (MW 7750), or poly (methacrylic acid) -sodium Salt (PMAA-Na Salt) (MW 1270). They are available from Sigma Aldrich (Sigma Aldrich).

In addition, in the above aspect, the inorganic substance may be surface-treated with 2-methacryloyloxyethyl phosphorylcholine (2- (methacryloyloxy) ethyl phosphorylcholine, MPC) or poly (methacrylic acid). Such surface treatment can be achieved by reacting the surface of an inorganic substance with a coupling agent and then uniformly coating 2-Methacryloyloxyethyl Phosphorylcholine (MPC) or poly (methacrylic acid), which is a biocompatible polymer, on the surface of the inorganic substance by, for example, a grafting method, but the surface treatment method is not limited thereto, and may be based on, for example, a known method such as the method disclosed in korean patent No. 2012-0065929.

In the aspect as described above, the above negatively charged substance may be contained in an amount of 1 to 50% by weight based on the total weight of the composition for dust control. The content of the above negatively charged substance is not limited, and may be 1 to 40 wt%, 1 to 30 wt%, 1 to 20 wt%, 1 to 10 wt%, 1 to 8 wt%, 1 to 6 wt%, or 1 to 4 wt%.

In the aspect described above, the composition can be used for dust control of fine dust having a particle size of 10 μm or less. The particle size is not limited, and may be 100 μm or less, 90 μm or less, 70 μm or less, 50 μm or less, 30 μm or less, 20 μm or less, 15 μm or less, or 10 μm or less.

In the aspect as described above, the above-mentioned composition for dust prevention may be a cosmetic composition, and the cosmetic composition may be a cosmetic composition for make-up, and particularly may be a powder or a compact.

In the present specification, "cosmetic" may refer to all substances having not only a cosmetic function but also a medical function in addition to the cosmetic function.

Specifically, examples of the cosmetic composition include a base cosmetic, a makeup cosmetic, a hair care cosmetic, a body cosmetic, and the like, and the formulation thereof is not particularly limited and may be appropriately selected depending on the purpose.

For example, the cosmetic composition may be in the form of a solution, a suspension, an emulsion, an ointment, a gel, a cream, a lotion, a powder, a soap, a surfactant-containing facial cleanser, an oil, a powder foundation, an emulsion foundation, a wax foundation, a spray, etc., but is not limited thereto. More specifically, it can be made into basic cosmetics such as softening lotion, nourishing lotion, skin lotion, nourishing cream, massage cream, moisturizing cream, hand cream, essence, eye cream, makeup removing foam, makeup removing lotion, facial mask, gel, patch, oil-in-water (O/W) type, and water-in-oil (O/W) type; makeup cosmetics such as lipsticks, foundation cream or foundation; cleaning products such as shampoo, hair conditioner, bath lotion, toothpaste or gargle; hair tonic, hair gel or mousse; hair cosmetic compositions such as hair restorer and hair dye.

The present invention in another aspect may relate to a method for preventing dust, comprising the step of applying a composition comprising, as an effective ingredient, a negatively charged substance having a ZETA potential value of-2 mV or less in an aqueous solution having a pH of 7, the negatively charged substance being a high molecular or inorganic substance, to skin.

In another aspect, the present invention can relate to the use of a negatively charged substance which is a polymer or inorganic substance and has a ZETA potential value of-2 mV or less in an aqueous solution having a pH of 7 for dust control.

In another aspect, the present invention relates to the use of a negatively charged substance for producing a composition for dust control, which comprises, as an active ingredient, a negatively charged substance having a ZETA potential value of-2 mV or less in an aqueous solution having a pH of 7, the negatively charged substance being a polymer or an inorganic substance.

The present invention will be described more specifically with reference to the following examples. However, the following examples are provided for illustrative purposes only to aid understanding of the present invention, and the scope of the present invention are not limited thereto.

Example 1 ZETA potential analysis of dust and yellow sand Standard substance and dust substitute substance screening

In order to screen the dust-substitute substances used for the confirmation of the dustproof effect of the present invention, the ZETA potentials of the post-complement group of the fine dust and the yellow sand, the dust-substitute substances were analyzed. The ZETA potential was measured by a Zetasizer nanometer particle size analyzer (Zetasizer Nano Instrument) (Malvern Co.). After filling a sample in a colloidal state or an emulsion state with a syringe so that air bubbles are not generated in the Zeta cell, the Zeta cell (Zeta cell) was closed with a cap, and then the Zeta cell was inserted into the Zeta sizer, and the Zeta potential was measured.

The results are shown in table 1 below.

[ Table 1]

In parentheses, the origin of each substance is shown.

Since the fine dust is generally composed of 22% of organic carbon compounds, 8% of carbon elements, 22% of nitrates, 15% of sulfates, 15% of soil crust components and 18% of others (national academy of sciences), carbon black which occupies about 30% of the constituents of the fine dust (organic carbon compounds and carbon elements) and has a similar ZETA potential to the fine dust is screened as a substitute for the fine substance in the present invention.

EXAMPLE 2 measurement of dust-proofing Effect

Example 2-1 leather test

The ZETA potential values of the after-replenishing substances used in the composition for preventing dust are shown in the following Table 2.

[ Table 2]

The post-supplement substances described in table 2 were added to the dosage form examples described in table 3 to prepare dust-proofing cosmetic compositions (1: control group, 2: PMAA-containing sodium salt (MW 75100), 3: PMAA-containing sodium salt (MW 18500), 4: PMAA-containing sodium salt (MW 7750), 5: phosphoipon 100, 6: MPC-TiO-containing)₂7: PMAA-sodium containing solution, 8: phospholipon90, 9: containing titanium oxide (TiO)₂(Titanium Oxide)), 10: containing PMAA-TiO₂11: control, 12: containing ZnO, 13: alumina, 14: containing chitosan). The substances used in the experiments were PMAA-sodium Salt (PMAA-NaSalt) (MW 75100), PMAA-sodium Salt (PMAA-Na Salt) (MW 18500), PMAA-sodium Salt (PMAA-Na Salt) (MW 7750), PMAA-sodium Salt (PMAA-Na Salt) (MW 1270), PMAA-sodium solution (PMAA-Na solution,434507ALDRICH), and Poisson sprayPoisson hill spray 90 (Phospholipon)) And Poisson spray 75 (Phospholipon)) Starting from sigma aldrich. In addition, MPC-TiO₂And PMAA-TiO₂By reacting a coupling agent with TiO having-OH functional groups₂After the surface reaction, the MPC polymer and PMAA polymer are coated at 0.1 to 10 wt% (more specifically, 3 wt%), and then filtered and pulverized.

Each of these compositions was uniformly applied to each artificial leather, dried for 10 minutes, and then added to a convection box containing 3.125g of carbon black (which is a level 500000 times the level of the fine dust alarm level of the korean weather hall), and after the air in the convection box was sufficiently convected by a convection circulation device, the carbon black remaining on the artificial leather was confirmed by the naked eye. As a result, the least carbon black was detected on the leather coated with the cosmetic composition containing PMAA-sodium salt (mw ═ 75100) having the highest absolute value of negative charge of ZETA potential, and PMAA-sodium salt (mw ═ 75100), PMAA-sodium salt (mw ═ 18500), PMAA-sodium salt (mw ═ 7750), PMAA-sodium salt solution, and phosplipon 100 (Phospholipon) were known) Has a dustproof effect (figure 1).

Example 2-2 Artificial Hair test

The post-supplement substances described in table 2 were added to the formulations described in table 6 to prepare fogging (blank: control, sample 1: containing PMAA-sodium salt (mw ═ 75100), sample 2: containing PMAA-sodium salt (mw ═ 18500), sample 3: containing phospholipon100, and sample 4: titanium dioxide surface-treated with MPC (MPC-TiO)₂) Sample 5: PMAA-sodium, sample 6: titanium dioxide surface treated with PMAA (PMAA-TiO)₂)). The same hair samples were sprayed with the mists, and the mass of the hair was measured after carbon black treatment in a convection box under the same conditions as in example 2-1. The larger the absolute value of the ZETA potential negative charge is, the smaller the amplitude of the increase in the mass of the hair is, and the larger the absolute value of the ZETA potential negative charge is, the more excellent the dustproof effect is (fig. 2).

Hereinafter, examples of the formulation of the composition according to the present invention will be described, but the pharmaceutical composition and the cosmetic composition may be applied in various formulations, which are only for the purpose of specific description and are not intended to limit the present invention.

[ Table 3]

Softening lotion (skin lotion)

Compounding ingredients	By weight%
		Purified water	Balance of
Negatively charged species	10.0
		Ethylenediaminetetraacetic acid	0.02
Glycerol	5
		Butanediol	3
PEG/PPG-17/6 copolymer (copolymer)	3
		Ethanol	5
Polyoxyethylene hydrogenated castor oil	0.4
		P-hydroxybenzoic acid methyl ester	0.1
Aromatic (fragance)	0.1
		Antiseptic, pigment, and perfume	Proper amount of

[ Table 4]

Smoothing toner (emulsion)

Compounding ingredients	Content (wt.)
		Purified water	Balance of
Negatively charged species	10.0
		Beeswax (Cera flava)	4.0
Polysorbate 60	1.5
		Sorbitan sesquioleate	1.5
Liquid paraffin	0.5
		Caprylic/capric triglyceride	5.0
Glycerol	3.0
		Butanediol	3.0
Propylene glycol	3.0
		Carboxyvinyl polymer	0.1
Triethanolamine	0.2
		Antiseptic, pigment, and perfume	Proper amount of

[ Table 5]

Powder or pressed powder cosmetic

Compounding ingredients	By weight%
		Negatively charged species	10.0
Nylon powder	5.0
		Modification ofStarch	3.0
Titanium dioxide	3.0
		Mica	25.0
Squalene	0.5
		Polydimethylsiloxane	0.8
Antiseptic, pigment, and perfume	Proper amount of
		Silicone treated talc	To 100

[ Table 6]

Hair spray

Compounding ingredients	Content (wt.)
		Purified water	To 100
Negatively charged species	10
		Glycerol	5.0
Butanediol	5.0
		Phenoxyethanol	0.5
PEG/PPG block copolymers	1.5
		Sodium chloride	0.3
Ethanol	3
		Polydimethylsiloxane	10

The above-mentioned mists were produced using a homogenizer without an emulsification process.

[ Table 7]

Nutrition paste

Compounding ingredients	Content (wt.)
		Purified water	Balance of
Negatively charged species	5.0
		Beeswax (Cera flava)	10.0
Polysorbate 60	1.5
		PEG60 hydrogenated Castor oil	2.0
Sorbitan sesquioleate	0.5
		Liquid paraffin	10.0
Squalane	5.0
		Caprylic/capric triglyceride	5.0
Glycerol	5.0
		Butanediol	3.0
Propylene glycol	3.0
		Triethanolamine	0.2
Antiseptic, pigment, and perfume	Proper amount of

Claims

1. A composition for dust control comprises a negatively charged substance having a ZETA potential value of-2 mV or less in an aqueous solution having a pH of 7 as an active ingredient,

the negatively charged substance is a polymer or an inorganic substance.

2. The composition for dust control according to claim 1, wherein the negatively charged substance has a ZETA potential value of-10 mV or less in an aqueous solution having a pH of 7.

3. The composition for dust control according to claim 2, wherein the value of ZETA potential of said negatively charged substance in an aqueous solution of pH 7 is from-50 mV to-10 mV.

4. The composition for dust control according to claim 1, wherein the polymer is a phospholipid or a poly (methacrylate).

5. The composition for dust control according to claim 1, wherein the inorganic substance is silicon dioxide (SiO)₂) Or titanium dioxide (TiO)₂)。

6. The composition for dust control according to claim 4, wherein the phospholipid is selected from the group consisting of phosphatidylglycerol, phosphatidylethanolamine, phosphatidylserine, polyethylene glycol phospholipid, sphingomyelin, and phosphatidylcholine.

7. The composition for dust control according to claim 6, wherein the phosphatidylcholine contains hydrogenated phosphatidylcholine.

8. The composition for dust control according to claim 4, wherein the poly (methacrylate) comprises a poly (methacrylic acid) sodium salt.

9. The composition for dust control according to claim 1, wherein the inorganic substance is surface-treated with 2-methacryloyloxyethylphosphonic acid choline (MPC) or poly (methacrylic acid).

10. The composition for dust control according to claim 1, wherein the negatively charged substance is contained in an amount of 1 to 50% by weight based on the total weight of the composition.

11. The composition for dust control according to claim 1, wherein the composition is used for dust control of fine dust having a particle size of 10 μm or less.

12. The composition according to any one of claims 1 to 11, wherein the composition for dust control is a cosmetic composition.

13. The cosmetic composition of claim 12, wherein the cosmetic composition is a cosmetic composition.

14. The cosmetic composition of claim 13, wherein the cosmetic composition is a powder or a pressed powder.