HK1245792A1 - 製備α-甲酰胺吡咯烷衍生物的方法 - Google Patents
製備α-甲酰胺吡咯烷衍生物的方法Info
- Publication number
- HK1245792A1 HK1245792A1 HK18105454.8A HK18105454A HK1245792A1 HK 1245792 A1 HK1245792 A1 HK 1245792A1 HK 18105454 A HK18105454 A HK 18105454A HK 1245792 A1 HK1245792 A1 HK 1245792A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pyrrolidine derivatives
- preparing alpha
- carboxamide pyrrolidine
- carboxamide
- alpha
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201423107 | 2014-12-23 | ||
| PCT/GB2015/054140 WO2016102967A1 (en) | 2014-12-23 | 2015-12-23 | Process for preparing alpha-carboxamide pyrrolidine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1245792A1 true HK1245792A1 (zh) | 2018-08-31 |
Family
ID=55066669
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK18105454.8A HK1245792A1 (zh) | 2014-12-23 | 2018-04-26 | 製備α-甲酰胺吡咯烷衍生物的方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10421716B2 (zh) |
| EP (1) | EP3237379B1 (zh) |
| ES (1) | ES2912881T3 (zh) |
| HK (1) | HK1245792A1 (zh) |
| WO (1) | WO2016102967A1 (zh) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10421716B2 (en) | 2014-12-23 | 2019-09-24 | Convergence Pharmaceuticals Limited | Process for preparing alpha-carboxamide pyrrolidine derivatives |
| EP3634400A4 (en) * | 2017-05-19 | 2021-06-09 | Biogen MA Inc. | NEW CRYSTALLINE SHAPES |
| WO2019071162A2 (en) * | 2017-10-05 | 2019-04-11 | Biogen Inc. | PROCESS FOR THE PREPARATION OF PYRROLIDINE ALPHA-CARBOXAMIDE DERIVATIVES |
| JP2022526431A (ja) * | 2019-04-10 | 2022-05-24 | バイオジェン インコーポレイテッド | アルファ－カルボキサミドピロリジン誘導体を調製するためのプロセス |
| MX2021012420A (es) * | 2019-04-10 | 2022-02-10 | Biogen Ma Inc | Proceso para preparar derivados de pirrolidina alfa-carboxamida. |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH674205A5 (zh) | 1988-05-11 | 1990-05-15 | Lonza Ag | |
| IL94466A (en) | 1989-05-25 | 1995-01-24 | Erba Carlo Spa | Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation |
| US6201016B1 (en) | 1994-06-27 | 2001-03-13 | Cytomed Incorporated | Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders |
| GB9727523D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
| CZ20013435A3 (cs) | 1999-03-26 | 2002-04-17 | Euro-Celtique S. A. | Aryly substituované pyrazoly, imidazoly, oxazoly, thiazoly a pyrroly a jejich pouľití |
| GB9923748D0 (en) | 1999-10-07 | 1999-12-08 | Glaxo Group Ltd | Chemical compounds |
| GB0115517D0 (en) | 2001-06-25 | 2001-08-15 | Ferring Bv | Novel antidiabetic agents |
| MY134480A (en) | 2002-09-20 | 2007-12-31 | Hoffmann La Roche | 4-pyrrolidino-phenyl-benzyl ether derivatives |
| AR044503A1 (es) | 2003-03-18 | 2005-09-14 | Merck & Co Inc | Triazoles sustituidos con biarilo como bloqueantes del canal de sodio |
| JP2006522130A (ja) | 2003-04-03 | 2006-09-28 | メルク エンド カムパニー インコーポレーテッド | ナトリウムチャンネル遮断薬としてのビアリール置換ピラゾール |
| EP1618099A4 (en) | 2003-04-18 | 2008-07-16 | Merck & Co Inc | BIARYLSUBSTITUTED DIAZOLE, OXAZOLE AND IMIDAZOLE AS SODIUM CHANNEL BLOCKERS |
| WO2005000309A2 (en) | 2003-06-27 | 2005-01-06 | Ionix Pharmaceuticals Limited | Chemical compounds |
| EP1524265A1 (en) | 2003-10-15 | 2005-04-20 | Newron Pharmaceuticals S.p.A. | Prolinamide derivatives as sodium and/or calcium channel blockers or selective MAO-B inhibitors |
| US7253168B2 (en) | 2004-04-07 | 2007-08-07 | Neurogen Corporation | Substituted 1-benzyl-4-substituted piperazine analogues |
| WO2005100334A1 (en) | 2004-04-14 | 2005-10-27 | Pfizer Products Inc. | Dipeptidyl peptidase-iv inhibitors |
| US7858786B2 (en) | 2005-05-04 | 2010-12-28 | Vertex Pharmaceuticals Incoropated | Pyrimidines and pyrazines useful as modulators of ion channels |
| JP2008540438A (ja) | 2005-05-04 | 2008-11-20 | バーテックス ファーマシューティカルズ インコーポレイテッド | イオンチャネルのモジュレーターとして有用なピリジン |
| WO2006124865A2 (en) | 2005-05-19 | 2006-11-23 | Vertex Pharmaceuticals Incorporated | Biaryls derivatives useful as modulators of ion channels |
| KR101292348B1 (ko) | 2005-09-09 | 2013-09-09 | 네르 쎄라퓨틱스 리미티드 | 피리딘 유도체 및 그의 정신병적 장애의 치료에 있어서의용도 |
| WO2007042250A1 (en) | 2005-10-10 | 2007-04-19 | Glaxo Group Limited | Prolinamide derivatives as sodium channel modulators |
| TW200728258A (en) | 2005-10-10 | 2007-08-01 | Glaxo Group Ltd | Novel compounds |
| TW200730494A (en) * | 2005-10-10 | 2007-08-16 | Glaxo Group Ltd | Novel compounds |
| GB0701366D0 (en) | 2007-01-24 | 2007-03-07 | Glaxo Group Ltd | Novel pharmaceutical compositions |
| GB0701365D0 (en) | 2007-01-24 | 2007-03-07 | Glaxo Group Ltd | Novel pharmaceutical compositions |
| JP2010516734A (ja) | 2007-01-24 | 2010-05-20 | グラクソ グループ リミテッド | ３，５−ジアミノ−６−（２，３−ジクロロフェニル）−１，２，４−トリアジンまたはｒ（−）−２，４−ジアミノ−５−（２，３−ジクロロフェニル）−６−フルオロメチルピリミジンを含む医薬組成物 |
| GB0706630D0 (en) | 2007-04-04 | 2007-05-16 | Glaxo Group Ltd | Novel compounds |
| JP2013501026A (ja) | 2009-08-05 | 2013-01-10 | クオンベルゲンセ プハルマセウトイカルス リミテッド | てんかん及び関連疾患の治療のための共治療法 |
| JP5855000B2 (ja) | 2009-09-14 | 2016-02-09 | クオンベルゲンセ プハルマセウトイカルス リミテッド | α−カルボキサミド誘導体の製造方法 |
| CA2810475C (en) | 2010-11-11 | 2016-09-13 | Aarti Healthcare Limited | A method for preparing ramipril |
| US10421716B2 (en) | 2014-12-23 | 2019-09-24 | Convergence Pharmaceuticals Limited | Process for preparing alpha-carboxamide pyrrolidine derivatives |
-
2015
- 2015-12-23 US US15/539,381 patent/US10421716B2/en active Active
- 2015-12-23 WO PCT/GB2015/054140 patent/WO2016102967A1/en active Application Filing
- 2015-12-23 EP EP15817522.4A patent/EP3237379B1/en active Active
- 2015-12-23 ES ES15817522T patent/ES2912881T3/es active Active
-
2018
- 2018-04-26 HK HK18105454.8A patent/HK1245792A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3237379B1 (en) | 2022-04-06 |
| ES2912881T3 (es) | 2022-05-30 |
| US20170369437A1 (en) | 2017-12-28 |
| WO2016102967A1 (en) | 2016-06-30 |
| US10421716B2 (en) | 2019-09-24 |
| EP3237379A1 (en) | 2017-11-01 |
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