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HK123694A - (1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives - Google Patents

(1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives Download PDF

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Publication number
HK123694A
HK123694A HK123694A HK123694A HK123694A HK 123694 A HK123694 A HK 123694A HK 123694 A HK123694 A HK 123694A HK 123694 A HK123694 A HK 123694A HK 123694 A HK123694 A HK 123694A
Authority
HK
Hong Kong
Prior art keywords
parts
formula
imidazol
compound
alkyl
Prior art date
Application number
HK123694A
Other languages
German (de)
English (en)
French (fr)
Inventor
H. M. Raeymaekers Alfons
J. E. Freyne Eddy
C. Sanz Gerard
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of HK123694A publication Critical patent/HK123694A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK123694A 1986-09-15 1994-11-10 (1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives HK123694A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US90790386A 1986-09-15 1986-09-15

Publications (1)

Publication Number Publication Date
HK123694A true HK123694A (en) 1994-11-18

Family

ID=25424835

Family Applications (1)

Application Number Title Priority Date Filing Date
HK123694A HK123694A (en) 1986-09-15 1994-11-10 (1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives

Country Status (23)

Country Link
EP (1) EP0260744B1 (ko)
JP (1) JPS6485975A (ko)
KR (1) KR960014353B1 (ko)
CN (1) CN1020903C (ko)
AU (1) AU595064B2 (ko)
BG (1) BG61321B2 (ko)
CA (1) CA1323366C (ko)
CY (1) CY1803A (ko)
DE (1) DE3783107T2 (ko)
DK (1) DK174728B1 (ko)
ES (1) ES2053524T3 (ko)
FI (1) FI87781C (ko)
GR (1) GR3006841T3 (ko)
HK (1) HK123694A (ko)
HU (1) HU198039B (ko)
IE (1) IE60514B1 (ko)
IL (1) IL83892A (ko)
NO (1) NO167202C (ko)
NZ (1) NZ221729A (ko)
PH (1) PH25022A (ko)
PT (1) PT85692B (ko)
SU (1) SU1662350A3 (ko)
ZA (1) ZA876881B (ko)

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US6288100B1 (en) * 1995-06-06 2001-09-11 American Home Products Corporation Benzimidazole derivatives
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FR2751649B1 (fr) * 1996-07-26 1998-08-28 Adir Nouveaux derives de benzimidazole, de benzoxazole et de benzothiazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
IT1286866B1 (it) * 1996-10-28 1998-07-17 Menarini Farma Ind Composti furano-eterociclici,loro preparazione ed uso come inibitori di aromatasi
CN1104422C (zh) * 1996-11-25 2003-04-02 普罗克特和甘保尔公司 用作α-2肾上腺素能受体兴奋剂的胍基杂环化合物
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TW453999B (en) 1997-06-27 2001-09-11 Fujisawa Pharmaceutical Co Benzimidazole derivatives
PT1037880E (pt) 1997-12-11 2004-11-30 Janssen Pharmaceutica Nv Anilidas mimeticas do acido retinoico
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US6858598B1 (en) 1998-12-23 2005-02-22 G. D. Searle & Co. Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6833373B1 (en) 1998-12-23 2004-12-21 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
JP2003501418A (ja) * 1999-06-04 2003-01-14 エラン ファーマ インターナショナル,リミティド 細胞死を阻害するための組成物および方法
EP1265853A1 (en) 2000-03-16 2002-12-18 F. Hoffmann-La Roche AG Carboxylic acid derivatives as ip antagonists
KR100725442B1 (ko) 2000-11-17 2007-06-07 다케다 야쿠힌 고교 가부시키가이샤 신규 이미다졸 유도체, 이의 제조 방법 및 이의 용도
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US7405235B2 (en) 2001-05-04 2008-07-29 Paratek Pharmaceuticals, Inc. Transcription factor modulating compounds and methods of use thereof
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JP2024536342A (ja) * 2021-10-04 2024-10-04 ボルト バイオセラピューティクス、インコーポレーテッド 非対称ビス-ベンゾイミダゾールstingアゴニスト免疫複合体及びその使用

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Also Published As

Publication number Publication date
FI87781B (fi) 1992-11-13
FI87781C (fi) 1993-02-25
NZ221729A (en) 1989-07-27
DK479487D0 (da) 1987-09-14
EP0260744A2 (en) 1988-03-23
AU7838587A (en) 1988-04-14
IE60514B1 (en) 1994-07-27
SU1662350A3 (ru) 1991-07-07
DE3783107D1 (de) 1993-01-28
NO873840L (no) 1988-03-16
FI873977A0 (fi) 1987-09-14
IL83892A (en) 1991-11-21
IE872487L (en) 1988-03-15
CA1323366C (en) 1993-10-19
DK479487A (da) 1988-03-16
CN1020903C (zh) 1993-05-26
PT85692B (pt) 1990-06-29
JPH0587071B2 (ko) 1993-12-15
ZA876881B (en) 1989-04-26
GR3006841T3 (ko) 1993-06-30
KR960014353B1 (ko) 1996-10-15
CN87106423A (zh) 1988-04-20
HUT45051A (en) 1988-05-30
DE3783107T2 (de) 1993-04-22
NO167202B (no) 1991-07-08
CY1803A (en) 1987-09-09
IL83892A0 (en) 1988-02-29
ES2053524T3 (es) 1994-08-01
DK174728B1 (da) 2003-10-06
HU198039B (en) 1989-07-28
PH25022A (en) 1991-01-28
FI873977A7 (fi) 1988-03-16
NO167202C (no) 1991-10-16
JPS6485975A (en) 1989-03-30
PT85692A (en) 1987-10-01
NO873840D0 (no) 1987-09-14
EP0260744B1 (en) 1992-12-16
BG61321B2 (bg) 1997-05-30
EP0260744A3 (en) 1989-01-18
KR880003935A (ko) 1988-06-01
AU595064B2 (en) 1990-03-22

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Effective date: 20070908