HK1218765A1 - 多適配子靶標檢測 - Google Patents
多適配子靶標檢測Info
- Publication number
- HK1218765A1 HK1218765A1 HK16106780.3A HK16106780A HK1218765A1 HK 1218765 A1 HK1218765 A1 HK 1218765A1 HK 16106780 A HK16106780 A HK 16106780A HK 1218765 A1 HK1218765 A1 HK 1218765A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- multiaptamer
- target detection
- target
- detection
- multiaptamer target
- Prior art date
Links
- 238000001514 detection method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1048—SELEX
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/33—Chemical structure of the base
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/10—Applications; Uses in screening processes
- C12N2320/13—Applications; Uses in screening processes in a process of directed evolution, e.g. SELEX, acquiring a new function
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/205—Aptamer
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361881629P | 2013-09-24 | 2013-09-24 | |
| PCT/US2014/057143 WO2015048084A1 (en) | 2013-09-24 | 2014-09-24 | Multiaptamer target detection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1218765A1 true HK1218765A1 (zh) | 2017-03-10 |
Family
ID=52744404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16106780.3A HK1218765A1 (zh) | 2013-09-24 | 2016-06-13 | 多適配子靶標檢測 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9926566B2 (zh) |
| EP (1) | EP3049523B1 (zh) |
| JP (1) | JP6506768B2 (zh) |
| KR (1) | KR102348283B1 (zh) |
| CN (2) | CN114703193A (zh) |
| AU (1) | AU2014326975B2 (zh) |
| BR (1) | BR112016005957A2 (zh) |
| CA (1) | CA2924987C (zh) |
| HK (1) | HK1218765A1 (zh) |
| IL (1) | IL244284B (zh) |
| MX (1) | MX361451B (zh) |
| SG (1) | SG11201602063UA (zh) |
| WO (1) | WO2015048084A1 (zh) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2924987C (en) | 2013-09-24 | 2022-08-16 | Somalogic, Inc. | Multiaptamer target detection |
| RU2708170C2 (ru) | 2014-11-24 | 2019-12-04 | Сомалоджик, Инк. | Соединения нуклеиновой кислоты для связывания ростового фактора дифференцировки 11 |
| CA3006792A1 (en) * | 2015-12-08 | 2017-06-15 | Twinstrand Biosciences, Inc. | Improved adapters, methods, and compositions for duplex sequencing |
| RU2750989C2 (ru) | 2016-03-14 | 2021-07-07 | Сомалоджик, Инк. | Композиции и способы синтеза 5-(n-защищенного триптаминкарбоксамида)-2'-дезоксиуридинфосфорамидита для включения в нуклеиновую кислоту |
| CA3037855A1 (en) * | 2016-06-17 | 2017-12-21 | Proximity Biosciences, Llc | Method for aptamer pair selection |
| WO2018005974A1 (en) * | 2016-07-01 | 2018-01-04 | Somalogic, Inc. | Oligonucleotides comprising modified nucleosides |
| CN110249082B (zh) | 2016-12-01 | 2023-07-07 | 诺迪勒思附属公司 | 测定蛋白质的方法 |
| WO2019103131A1 (ja) * | 2017-11-24 | 2019-05-31 | 国立大学法人 東京大学 | アプタマーの結合部位判別方法、アプタマーペアおよび目的物質からなる三元錯体の解離定数等の測定方法並びに最適なアプタマーペアの選択方法 |
| JP7458678B2 (ja) | 2017-12-29 | 2024-04-01 | ノーティラス・サブシディアリー・インコーポレイテッド | タンパク質同定のためのデコーディングアプローチ方法 |
| JP7526102B2 (ja) | 2018-06-22 | 2024-07-31 | ソマロジック・オペレイティング・カンパニー・インコーポレイテッド | 改良されたプロテオミクスマルチプレックスアッセイ |
| EP4165549A1 (en) | 2020-06-11 | 2023-04-19 | Nautilus Biotechnology, Inc. | Methods and systems for computational decoding of biological, chemical, and physical entities |
| US12092642B2 (en) | 2021-01-20 | 2024-09-17 | Nautilus Subsidiary, Inc. | Systems and methods for biomolecule quantitation |
| CA3203535A1 (en) | 2021-01-21 | 2022-07-28 | Gregory KAPP | Systems and methods for biomolecule preparation |
| AU2022232933A1 (en) | 2021-03-11 | 2023-09-07 | Nautilus Subsidiary, Inc. | Systems and methods for biomolecule retention |
| CA3227872A1 (en) | 2021-09-09 | 2023-03-16 | James Henry JOLY | Characterization and localization of protein modifications |
| WO2023049073A1 (en) | 2021-09-22 | 2023-03-30 | Nautilus Biotechnology, Inc. | Methods and systems for determining polypeptide interactions |
| WO2023081728A1 (en) | 2021-11-03 | 2023-05-11 | Nautilus Biotechnology, Inc. | Systems and methods for surface structuring |
| EP4500157A1 (en) | 2022-03-29 | 2025-02-05 | Nautilus Subsidiary, Inc. | Integrated arrays for single-analyte processes |
| US20230360732A1 (en) | 2022-04-25 | 2023-11-09 | Nautilus Subsidiary, Inc. | Systems and methods for assessing and improving the quality of multiplex molecular assays |
| WO2023250364A1 (en) | 2022-06-21 | 2023-12-28 | Nautilus Subsidiary, Inc. | Method for detecting analytes at sites of optically non-resolvable distances |
| WO2024059655A1 (en) | 2022-09-15 | 2024-03-21 | Nautilus Subsidiary, Inc. | Characterizing accessibility of macromolecule structures |
| WO2024073599A1 (en) | 2022-09-29 | 2024-04-04 | Nautilus Subsidiary, Inc. | Preparation of array surfaces for single-analyte processes |
| WO2024107857A1 (en) | 2022-11-15 | 2024-05-23 | Nautilus Subsidiary, Inc. | Standard polypeptides |
| US20240192202A1 (en) | 2022-12-09 | 2024-06-13 | Nautilus Subsidiary, Inc. | Fluidic media for single-analtye arrays |
| US20240201182A1 (en) | 2022-12-15 | 2024-06-20 | Nautilus Subsidiary, Inc. | Inhibition of photon phenomena on single molecule arrays |
| WO2024151373A1 (en) | 2023-01-12 | 2024-07-18 | Nautilus Subsidiary, Inc. | Characterization of glycans and glycoconjugates |
| WO2024206122A1 (en) | 2023-03-24 | 2024-10-03 | Nautilus Subsidiary, Inc. | Improved transfer of nanoparticles to array surfaces |
| WO2024216233A1 (en) | 2023-04-13 | 2024-10-17 | Nautilus Subsidiary, Inc. | Artificial proteins for displaying epitopes |
| WO2024243237A1 (en) | 2023-05-24 | 2024-11-28 | Nautilus Subsidiary, Inc. | Systems and methods for machine vision |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020037506A1 (en) * | 2000-04-18 | 2002-03-28 | Yun Lin | Aptamer based two-site binding assay |
| CA2425208C (en) * | 2000-09-26 | 2013-04-09 | Duke University | Rna aptamers and methods for identifying the same |
| US20070071744A1 (en) * | 2002-06-07 | 2007-03-29 | Gotz Munch | Agents which bind to epitopes of glycoprotein VI |
| US7595160B2 (en) | 2004-01-13 | 2009-09-29 | U.S. Genomics, Inc. | Analyte detection using barcoded polymers |
| US7795009B2 (en) * | 2005-06-15 | 2010-09-14 | Saint Louis University | Three-component biosensors for detecting macromolecules and other analytes |
| WO2007056250A2 (en) | 2005-11-04 | 2007-05-18 | U.S. Genomics, Inc. | Heterogeneous assay of analytes in solution using polymers |
| WO2008039642A2 (en) | 2006-09-26 | 2008-04-03 | Replidyne, Inc. | Methods and compounds for treatment of clostridium based infection |
| US7947447B2 (en) | 2007-01-16 | 2011-05-24 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| MX2010000578A (es) * | 2007-07-17 | 2010-04-30 | Somalogic Inc | Metodo para generar aptameros con constantes de disociacion mejoradas. |
| WO2009037264A2 (en) | 2007-09-17 | 2009-03-26 | Da Volterra | Colonic delivery of antimicrobial agents |
| US8569252B2 (en) | 2009-04-15 | 2013-10-29 | Postech Academy-Industry Foundation | Nucleolin specific aptamer and use thereof |
| CA2814762A1 (en) | 2010-02-11 | 2011-08-18 | Intelligent Medical Devices, Inc. | Oligonucleotides relating to clostridium difficile genes encoding toxin b, toxin a, or binary toxin |
| GB201002627D0 (en) | 2010-02-16 | 2010-03-31 | Loxbridge Res Llp | Aptamer based analyte detection method |
| CN104069512A (zh) * | 2010-04-12 | 2014-10-01 | 私募蛋白质体公司 | 针对β-NGF的适体及其在治疗β-NGF介导的疾病和失调中的用途 |
| US8785132B2 (en) * | 2010-04-23 | 2014-07-22 | Postech Academy-Industry Foundation | Aptamer sandwich assays |
| US20150031585A1 (en) | 2011-03-10 | 2015-01-29 | Somalogic, Inc. | Multiaptamer Target Detection |
| EP2683729B1 (en) | 2011-03-10 | 2017-05-03 | Somalogic, Inc. | Aptamers for clostridium difficile diagnostics |
| KR20140044324A (ko) * | 2011-04-26 | 2014-04-14 | 레가도 바이오사이언스, 인코포레이티드 | 페길화된 올리고뉴클레오티드의 제조방법 |
| BR122019023720B1 (pt) | 2011-09-30 | 2023-01-24 | Somalogic Operating Co., Inc | Kit de triagem de um indivíduo em uma população por meio de avaliação ou prognóstico do risco de um evento cardiovascular futuro dentro de um período de 5 anos |
| WO2013102096A1 (en) | 2011-12-30 | 2013-07-04 | Quest Diagnostics Investments Incorporated | Aptamers and diagnostic methods for detecting the egf receptor |
| CA2924987C (en) | 2013-09-24 | 2022-08-16 | Somalogic, Inc. | Multiaptamer target detection |
-
2014
- 2014-09-24 CA CA2924987A patent/CA2924987C/en active Active
- 2014-09-24 EP EP14847780.5A patent/EP3049523B1/en active Active
- 2014-09-24 WO PCT/US2014/057143 patent/WO2015048084A1/en active Application Filing
- 2014-09-24 MX MX2016003320A patent/MX361451B/es active IP Right Grant
- 2014-09-24 CN CN202210264586.7A patent/CN114703193A/zh active Pending
- 2014-09-24 SG SG11201602063UA patent/SG11201602063UA/en unknown
- 2014-09-24 JP JP2016544355A patent/JP6506768B2/ja active Active
- 2014-09-24 CN CN201480051210.1A patent/CN105555957A/zh active Pending
- 2014-09-24 BR BR112016005957A patent/BR112016005957A2/pt not_active IP Right Cessation
- 2014-09-24 US US15/023,182 patent/US9926566B2/en active Active
- 2014-09-24 AU AU2014326975A patent/AU2014326975B2/en active Active
- 2014-09-24 KR KR1020167006262A patent/KR102348283B1/ko active Active
-
2016
- 2016-02-25 IL IL244284A patent/IL244284B/en active IP Right Grant
- 2016-06-13 HK HK16106780.3A patent/HK1218765A1/zh unknown
-
2018
- 2018-02-13 US US15/895,723 patent/US10392621B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20160237435A1 (en) | 2016-08-18 |
| US10392621B2 (en) | 2019-08-27 |
| CN105555957A (zh) | 2016-05-04 |
| US9926566B2 (en) | 2018-03-27 |
| SG11201602063UA (en) | 2016-04-28 |
| JP6506768B2 (ja) | 2019-04-24 |
| AU2014326975B2 (en) | 2020-05-07 |
| MX2016003320A (es) | 2016-05-31 |
| CA2924987A1 (en) | 2015-04-02 |
| IL244284B (en) | 2019-12-31 |
| US20180187197A1 (en) | 2018-07-05 |
| AU2014326975A1 (en) | 2016-04-07 |
| EP3049523A1 (en) | 2016-08-03 |
| KR102348283B1 (ko) | 2022-01-10 |
| WO2015048084A1 (en) | 2015-04-02 |
| CA2924987C (en) | 2022-08-16 |
| MX361451B (es) | 2018-12-06 |
| CN114703193A (zh) | 2022-07-05 |
| EP3049523B1 (en) | 2019-08-07 |
| BR112016005957A2 (pt) | 2017-09-26 |
| IL244284A0 (en) | 2016-04-21 |
| KR20160058777A (ko) | 2016-05-25 |
| JP2016531593A (ja) | 2016-10-13 |
| AU2014326975A2 (en) | 2017-01-05 |
| EP3049523A4 (en) | 2017-05-17 |
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