HK1218658A1 - 蛋白酶 抑制劑及其方法和組合物 - Google Patents
蛋白酶 抑制劑及其方法和組合物Info
- Publication number
- HK1218658A1 HK1218658A1 HK16106596.7A HK16106596A HK1218658A1 HK 1218658 A1 HK1218658 A1 HK 1218658A1 HK 16106596 A HK16106596 A HK 16106596A HK 1218658 A1 HK1218658 A1 HK 1218658A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- methods
- proteinase inhibitors
- compositions therefor
- therefor
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13927908P | 2008-12-19 | 2008-12-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1218658A1 true HK1218658A1 (zh) | 2017-03-03 |
Family
ID=41819696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16106596.7A HK1218658A1 (zh) | 2008-12-19 | 2016-06-08 | 蛋白酶 抑制劑及其方法和組合物 |
Country Status (4)
Country | Link |
---|---|
US (2) | US8211637B2 (zh) |
EP (2) | EP2367954B1 (zh) |
HK (1) | HK1218658A1 (zh) |
WO (1) | WO2010071833A1 (zh) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE454469T1 (de) | 2002-01-28 | 2010-01-15 | Ambion Inc | Für den nachweis von nukleinsäuren kompetente biologische rohderivate |
US7964350B1 (en) | 2007-05-18 | 2011-06-21 | Applied Biosystems, Llc | Sample preparation for in situ nucleic acid analysis |
US8211637B2 (en) | 2008-12-19 | 2012-07-03 | Life Technologies Corporation | Proteinase K inhibitors, methods and compositions therefor |
CN104243495A (zh) * | 2014-10-11 | 2014-12-24 | 中国南方电网有限责任公司 | 一种jms服务跨反向隔离装置方法及系统 |
CN110146453B (zh) * | 2019-04-30 | 2020-06-12 | 东华大学 | 染料的筛选方法 |
US20210284989A1 (en) * | 2020-03-13 | 2021-09-16 | Promega Corporation | Sperm cell isolation and sperm-associated dna purification |
CN118510910A (zh) * | 2022-01-10 | 2024-08-16 | 塞提斯生物技术有限公司 | 用于处理含核酸样品的方法 |
Family Cites Families (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0124317B1 (en) | 1983-04-27 | 1990-04-11 | Ici Americas Inc. | Proline derivatives |
US4644055A (en) * | 1984-12-17 | 1987-02-17 | E. I. Du Pont De Nemours And Company | Method for preparing specific inhibitors of virus-specified proteases |
US5194588A (en) | 1985-01-22 | 1993-03-16 | Ici Americas Inc. | Aminoalcohol intermediates for peptide derivatives |
US5055450A (en) | 1985-01-22 | 1991-10-08 | Ici Americas Inc. | Peptide derivatives |
GB8600263D0 (en) | 1985-01-22 | 1986-02-12 | Ici America Inc | Peptide derivatives |
CA1317860C (en) | 1987-04-01 | 1993-05-18 | Daniel Louis Kacian | Techniques for preparing specimens for bacterial assays |
US5008245A (en) | 1988-10-27 | 1991-04-16 | University Of Kentucky Research Foundation | Novel peptidyl carbamate inhibitors of the enzyme elastase |
NO177716C (no) | 1989-06-09 | 1995-11-08 | Zeneca Ltd | Fremgangsmåte for fremstilling av terapeutisk aktive polypeptider, DNA-sekvens, ekspresjonsvektor og antistoff |
CA2021660A1 (en) | 1989-07-26 | 1991-01-27 | Philippe Bey | Peptidase inhibitors |
US4997932A (en) | 1989-11-13 | 1991-03-05 | Boehringer Mannheim Corporation | Method and kit for purifying nucleic acids |
US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
US5284829A (en) | 1991-11-26 | 1994-02-08 | The Regents Of The University Of California | Synthetic tetrapeptides for the prevention of schistosome parasite infection |
EP0675965A4 (en) | 1992-01-29 | 1999-01-20 | Hitachi Chemical Co Ltd | CARRIERS FOR IMMOBILIZING POLYNUCLEOTIDES. |
KR100249110B1 (ko) | 1992-05-06 | 2000-04-01 | 다니엘 엘. 캐시앙 | 핵산 서열 증폭 방법, 이에 이용되는 조성물 및 키트 |
AU6776994A (en) | 1993-05-06 | 1994-12-12 | Abbott Laboratories | Direct lysis buffer and the detection of hiv-1 plasma viremia |
AU699232B2 (en) | 1994-03-10 | 1998-11-26 | Gen-Probe Incorporated | Method for suppressing inhibition of enzyme-mediated reactions by ionic detergents |
US5712095A (en) | 1994-06-16 | 1998-01-27 | Becton Dickinson And Company | Rapid and sensitive detection of antibiotic-resistant mycobacteria using oligonucleotide probes specific for ribosomal RNA precursors |
WO1996000228A1 (en) | 1994-06-23 | 1996-01-04 | Dade International Inc. | Method for the rapid isolation of nucleic acid |
US5554536A (en) * | 1995-01-05 | 1996-09-10 | Millipore Investment Holdings Limited | Biological analysis device having improved contamination prevention |
ES2347854T5 (es) | 1996-03-26 | 2014-07-24 | Michael S. Kopreski | Método que permite el uso de RNA extracelular extraído de plasma o suero para detectar, monitorizar o evaluar un cáncer |
US5939262A (en) | 1996-07-03 | 1999-08-17 | Ambion, Inc. | Ribonuclease resistant RNA preparation and utilization |
US6218105B1 (en) | 1996-07-19 | 2001-04-17 | Kathleen S. Hall | High throughput papilloma virus in vitro infectivity assay |
US5871628A (en) | 1996-08-22 | 1999-02-16 | The University Of Texas System | Automatic sequencer/genotyper having extended spectral response |
WO1998059076A1 (en) | 1997-06-25 | 1998-12-30 | Promega Corporation | Method of isolating rna |
US6111096A (en) | 1997-10-31 | 2000-08-29 | Bbi Bioseq, Inc. | Nucleic acid isolation and purification |
CA2317761A1 (en) | 1998-01-26 | 1999-07-29 | Basf Aktiengesellschaft | Thrombin inhibitors |
US6583301B1 (en) | 1998-04-08 | 2003-06-24 | Celltech R & D Limited | Lipids |
US6204375B1 (en) | 1998-07-31 | 2001-03-20 | Ambion, Inc. | Methods and reagents for preserving RNA in cell and tissue samples |
US6777210B1 (en) | 1998-09-24 | 2004-08-17 | Ambion, Inc. | Method and reagents for inactivating ribonucleases RNase A, RNase I and RNase T1 |
US6265165B1 (en) | 1998-11-12 | 2001-07-24 | The Regents Of The University Of California | Methods for EST-specific full length cDNA cloning |
WO2000034504A2 (en) | 1998-12-10 | 2000-06-15 | Genetic Vectors, Inc. | Method of protein removal |
DE19916534A1 (de) | 1999-04-13 | 2000-10-19 | Gsf Forschungszentrum Umwelt | RNA-Isolierungs-Kit |
ES2218185T3 (es) | 1999-07-23 | 2004-11-16 | Genentech, Inc. | Metodo para la purificacion de adn plasmidico exento de rnasa y de solvente organico, usando filtracion de flujo tangencial. |
DE60044977D1 (de) | 1999-09-24 | 2010-10-28 | Ambion Inc | Cocktail von nukleaseinhibitoren |
US7264932B2 (en) | 1999-09-24 | 2007-09-04 | Applera Corporation | Nuclease inhibitor cocktail |
AU3074001A (en) | 1999-12-09 | 2001-06-18 | Advanced Research And Technology Institute, Inc. | Fluorescent in situ rt-pcr |
US7001724B1 (en) | 2000-11-28 | 2006-02-21 | Applera Corporation | Compositions, methods, and kits for isolating nucleic acids using surfactants and proteases |
JP2004523229A (ja) | 2001-01-16 | 2004-08-05 | インヴィトロジェン コーポレーション | Rna単離のための試薬 |
US20020172972A1 (en) | 2001-05-15 | 2002-11-21 | President And Fellows Of Harvard College | Use of a selectively inactivatable enzyme to digest contaminating nucleic acid |
DE60229958D1 (de) * | 2001-06-28 | 2009-01-02 | Mountain View Pharmaceuticals | Polymerstabilisierte proteinasen |
ATE454469T1 (de) | 2002-01-28 | 2010-01-15 | Ambion Inc | Für den nachweis von nukleinsäuren kompetente biologische rohderivate |
US20040038213A1 (en) | 2002-08-06 | 2004-02-26 | Kwon Jai W. | Genotyping by in situ PCR amplification of a polynucleotide in a tissue biopsy |
US7214484B2 (en) | 2002-12-17 | 2007-05-08 | Sigma-Aldrich Co. | Compositions and methods for nucleic acid extraction from biological samples |
WO2004076640A2 (en) | 2003-02-25 | 2004-09-10 | Ambion, Inc. | Small-molecule inhibitors of angiogenin and rnases and in vivo and in vitro methods of using same |
US7067298B2 (en) | 2003-03-31 | 2006-06-27 | Ambion, Inc. | Compositions and methods of using a synthetic Dnase I |
BRPI0409557B8 (pt) | 2003-04-04 | 2021-05-25 | Univ Lausanne | proteína recombinante inibidora de calicreína, sequência de dna, vetor de expressão, composição farmacêutica, uso da composição farmacêutica, método de produção da proteína recombinanete e kits de diagnóstico |
US20050069953A1 (en) | 2003-09-30 | 2005-03-31 | Ye Fang | Assay solution compositions and methods for GPCR arrays |
US20050277121A1 (en) | 2004-06-11 | 2005-12-15 | Ambion, Inc. | Crude biological derivatives competent for nucleic acid detection |
US20060088870A1 (en) | 2004-10-22 | 2006-04-27 | Finkelstein Sydney D | Topographic genotyping for determining the diagnosis, malignant potential, and biologic behavior of pancreatic cysts and related conditions |
US20060188892A1 (en) | 2005-02-18 | 2006-08-24 | Ambion, Inc. | Enzymatic digestion of tissue |
US7964350B1 (en) | 2007-05-18 | 2011-06-21 | Applied Biosystems, Llc | Sample preparation for in situ nucleic acid analysis |
US8211637B2 (en) | 2008-12-19 | 2012-07-03 | Life Technologies Corporation | Proteinase K inhibitors, methods and compositions therefor |
US12227408B2 (en) | 2023-01-11 | 2025-02-18 | Opw Fueling Components, Llc | Fluid dispensing device with reduced opening force |
-
2009
- 2009-12-18 US US12/642,322 patent/US8211637B2/en active Active
- 2009-12-18 EP EP09796899.4A patent/EP2367954B1/en active Active
- 2009-12-18 EP EP15155409.4A patent/EP2955233A1/en not_active Withdrawn
- 2009-12-18 WO PCT/US2009/068819 patent/WO2010071833A1/en active Application Filing
-
2012
- 2012-06-15 US US13/524,962 patent/US9114104B2/en active Active
-
2016
- 2016-06-08 HK HK16106596.7A patent/HK1218658A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
US20100159482A1 (en) | 2010-06-24 |
EP2367954B1 (en) | 2015-02-18 |
US20130004941A1 (en) | 2013-01-03 |
EP2367954A1 (en) | 2011-09-28 |
EP2955233A1 (en) | 2015-12-16 |
WO2010071833A1 (en) | 2010-06-24 |
US8211637B2 (en) | 2012-07-03 |
US9114104B2 (en) | 2015-08-25 |
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