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HK1210616A1 - 用於製備 激酶抑制劑的方法 - Google Patents

用於製備 激酶抑制劑的方法

Info

Publication number
HK1210616A1
HK1210616A1 HK15111400.4A HK15111400A HK1210616A1 HK 1210616 A1 HK1210616 A1 HK 1210616A1 HK 15111400 A HK15111400 A HK 15111400A HK 1210616 A1 HK1210616 A1 HK 1210616A1
Authority
HK
Hong Kong
Prior art keywords
fms
preparation
kinase inhibitors
fms kinase
inhibitors
Prior art date
Application number
HK15111400.4A
Other languages
English (en)
Inventor
Christopher A Teleha
Krzysztof Kolodziejczyk
Alfred Elisabeth Stappers
Koen Johan Herman Weerts
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1210616A1 publication Critical patent/HK1210616A1/zh

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    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
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    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
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  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Immunology (AREA)
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  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
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  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
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HK15111400.4A 2012-08-07 2015-11-19 用於製備 激酶抑制劑的方法 HK1210616A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261680446P 2012-08-07 2012-08-07
PCT/US2013/053602 WO2014025679A1 (en) 2012-08-07 2013-08-05 Process for the preparation of c-fms kinase inhibitors

Publications (1)

Publication Number Publication Date
HK1210616A1 true HK1210616A1 (zh) 2016-04-29

Family

ID=48980367

Family Applications (2)

Application Number Title Priority Date Filing Date
HK15110017.1A HK1209418A1 (zh) 2012-08-07 2015-10-14 用於製備 激酶抑制劑的方法
HK15111400.4A HK1210616A1 (zh) 2012-08-07 2015-11-19 用於製備 激酶抑制劑的方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK15110017.1A HK1209418A1 (zh) 2012-08-07 2015-10-14 用於製備 激酶抑制劑的方法

Country Status (13)

Country Link
US (2) US9029352B2 (zh)
EP (2) EP3091006B1 (zh)
JP (1) JP6290884B2 (zh)
CN (2) CN107266405A (zh)
AR (2) AR092070A1 (zh)
AU (2) AU2013299926B2 (zh)
ES (2) ES2607807T3 (zh)
HK (2) HK1209418A1 (zh)
IN (1) IN2015DN00660A (zh)
JO (2) JOP20180012A1 (zh)
TW (2) TWI608004B (zh)
UY (1) UY34972A (zh)
WO (1) WO2014025679A1 (zh)

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TW201811326A (zh) 2016-07-18 2018-04-01 比利時商健生藥品公司 ４－氰基－ｎ－（２－（４，４－二甲基環己－１－烯－１－基）－６－（２，２，６，６－四甲基四氫－２ｈ－哌喃－４－基）吡啶－３－基）－１ｈ－咪唑－２－甲醯胺之鹽形式
TWI752980B (zh) 2016-07-18 2022-01-21 比利時商健生藥品公司 4-氰基-n-(2-(4,4-二甲基環己-1-烯-1-基)-6-(2,2,6,6-四甲基四氫-2h-哌喃-4-基)吡啶-3-基)-1h-咪唑-2-甲醯胺之晶型
JP6831558B2 (ja) * 2016-08-23 2021-02-17 株式会社Ｈｂｃフナト 脳機能改善組成物
EP3589324A1 (en) * 2017-03-03 2020-01-08 Janssen Biotech, Inc. Co-therapy comprising a small molecule csf-1r inhibitor and an agonistic antibody that specifically binds cd40 for the treatment of cancer
WO2020222109A1 (en) 2019-05-02 2020-11-05 Janssen Biotech, Inc. Csf-1/csf-1r gene set

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