[go: up one dir, main page]

HK1210031A1 - Therapeutic agent or prophylactic agent for dementia - Google Patents

Therapeutic agent or prophylactic agent for dementia

Info

Publication number
HK1210031A1
HK1210031A1 HK15110820.8A HK15110820A HK1210031A1 HK 1210031 A1 HK1210031 A1 HK 1210031A1 HK 15110820 A HK15110820 A HK 15110820A HK 1210031 A1 HK1210031 A1 HK 1210031A1
Authority
HK
Hong Kong
Prior art keywords
agent
dementia
prophylactic
therapeutic agent
therapeutic
Prior art date
Application number
HK15110820.8A
Other languages
English (en)
Chinese (zh)
Inventor
森启
富山貴美
松本洋
江口廣志
九里裕
Original Assignee
Univ Osaka City
Teijin Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Osaka City, Teijin Pharma Ltd filed Critical Univ Osaka City
Publication of HK1210031A1 publication Critical patent/HK1210031A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
HK15110820.8A 2012-05-31 2015-11-03 Therapeutic agent or prophylactic agent for dementia HK1210031A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012124336 2012-05-31
PCT/JP2013/065090 WO2013180238A1 (ja) 2012-05-31 2013-05-30 認知症治療剤又は予防剤

Publications (1)

Publication Number Publication Date
HK1210031A1 true HK1210031A1 (en) 2016-04-15

Family

ID=49673425

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15110820.8A HK1210031A1 (en) 2012-05-31 2015-11-03 Therapeutic agent or prophylactic agent for dementia

Country Status (31)

Country Link
US (3) US20150183854A1 (es)
EP (2) EP2857039B1 (es)
JP (3) JP5971659B2 (es)
KR (2) KR102208283B1 (es)
CN (1) CN104602708B (es)
AR (1) AR091218A1 (es)
AU (2) AU2013268364B2 (es)
BR (1) BR112014029566A2 (es)
CA (1) CA2875205C (es)
CY (1) CY1122530T1 (es)
DK (1) DK2857039T3 (es)
ES (2) ES2973070T3 (es)
HK (1) HK1210031A1 (es)
HR (1) HRP20192267T1 (es)
HU (1) HUE046919T2 (es)
IL (1) IL235899B (es)
LT (1) LT2857039T (es)
ME (1) ME03587B (es)
MX (1) MX361128B (es)
MY (1) MY172458A (es)
NZ (1) NZ630536A (es)
PH (1) PH12014502669B1 (es)
PL (1) PL2857039T3 (es)
PT (1) PT2857039T (es)
RS (1) RS59802B1 (es)
RU (1) RU2657438C2 (es)
SG (2) SG10201805410XA (es)
SI (1) SI2857039T1 (es)
TW (2) TWI777183B (es)
WO (1) WO2013180238A1 (es)
ZA (1) ZA201409186B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2670434B1 (en) 2011-01-31 2018-12-26 Tau Bio-Logic Corp. Treatment of tauopathies
WO2012162179A1 (en) * 2011-05-20 2012-11-29 Oligomerix, Inc. Tau protease compositions and methods of use
ES2973070T3 (es) * 2012-05-31 2024-06-18 Univ Osaka Public Corp Agente terapéutico o agente profiláctico para la demencia
RU2668159C2 (ru) 2012-07-03 2018-09-26 Вашингтон Юниверсити Антитела против тау
TWI734975B (zh) * 2014-06-27 2021-08-01 美商C2N醫療診斷有限責任公司 人類化抗-tau抗體
WO2017189963A1 (en) * 2016-04-29 2017-11-02 Voyager Therapeutics, Inc. Compositions for the treatment of disease
WO2018060035A1 (en) * 2016-09-30 2018-04-05 F. Hoffmann-La Roche Ag Spr-based dual-binding assay for the functional analysis of multispecific molecules
MX2019009817A (es) 2017-02-17 2019-11-21 Denali Therapeutics Inc Anticuerpos anti-tau y metodos de uso de los mismos.
JP2018139530A (ja) * 2017-02-27 2018-09-13 帝人ファーマ株式会社 認知症治療又は予防のためのヒト化抗体及びその製造方法、並びにそれを用いた認知症治療剤又は予防剤
EP3636670A4 (en) 2017-05-30 2021-06-23 Teijin Pharma Limited ANTI-IGF-I RECEPTOR ANTIBODIES
MX2020003581A (es) 2017-10-02 2020-07-22 Merck Sharp & Dohme Compuestos monobactamicos cromanos para el tratamiento de infecciones bacterianas.
PE20210115A1 (es) 2017-10-16 2021-01-19 Eisai Randd Man Co Ltd Anticuerpos anti-tau y uso de los mismos
JP7504026B2 (ja) 2018-04-06 2024-06-21 帝人ファーマ株式会社 Spns2中和抗体
CN112469827B (zh) * 2018-07-04 2024-05-24 学校法人爱知医科大学 控制Tau的剪接的反义寡核苷酸及其用途
CN110028583B (zh) * 2019-05-07 2020-09-11 温州医科大学 抗Tau抗体及其在治疗阿尔茨海默病、创伤性脑损伤中的应用
JP7429404B2 (ja) * 2019-08-06 2024-02-08 慶應義塾 タウ関連疾患モデルの製造方法
JPWO2021065306A1 (es) 2019-09-30 2021-04-08
US20230137434A1 (en) * 2020-03-19 2023-05-04 Vascular Biosciences CAR Peptide for Improved Coronavirus Survival
EP4171633A1 (en) 2020-06-25 2023-05-03 Merck Sharp & Dohme LLC High affinity antibodies targeting tau phosphorylated at serine 413
US20250034559A1 (en) 2021-11-17 2025-01-30 Voyager Therapeutics, Inc. Compositions and methods for the treatment of tau-related disorders

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS587390B2 (ja) 1975-03-11 1983-02-09 ツキシマキカイ カブシキガイシヤ ア−クヨウセツホウホウ
JP3587390B2 (ja) 1994-03-17 2004-11-10 タカラバイオ株式会社 リン酸化アミノ酸誘導体及びリン酸化ペプチド合成方法
US20020086009A1 (en) * 1996-03-13 2002-07-04 Koichi Ishiguro Anti-phosphorylated tau protein antibodies and methods for detecting alzheimer`s disease with the use of the same
US20080199471A1 (en) * 2002-03-01 2008-08-21 Bernett Matthew J Optimized cd40 antibodies and methods of using the same
US8012936B2 (en) 2006-03-29 2011-09-06 New York University Tau fragments for immunotherapy
US20070280935A1 (en) * 2006-04-07 2007-12-06 Bernd Bohrmann Antibody that recognizes phosphorylated peptides
JP2009539406A (ja) * 2006-06-16 2009-11-19 エンビボ ファーマシューティカルズ インコーポレイテッド タウおよびアミロイド前駆体断片を発現する遺伝子組換えハエ
UA107571C2 (xx) * 2009-04-03 2015-01-26 Фармацевтична композиція
CN102596221B (zh) * 2009-06-10 2019-06-04 纽约大学 病理tau蛋白的免疫靶向
US8609097B2 (en) 2009-06-10 2013-12-17 Hoffmann-La Roche Inc. Use of an anti-Tau pS422 antibody for the treatment of brain diseases
EP2670434B1 (en) * 2011-01-31 2018-12-26 Tau Bio-Logic Corp. Treatment of tauopathies
TR201102696U (tr) * 2011-05-27 2011-06-21 Turhal Sal�H Bağlantısız hareketli ürün reklam standı.
ES2973070T3 (es) * 2012-05-31 2024-06-18 Univ Osaka Public Corp Agente terapéutico o agente profiláctico para la demencia

Also Published As

Publication number Publication date
KR20150027098A (ko) 2015-03-11
AU2013268364A1 (en) 2014-12-18
SG11201407878VA (en) 2015-01-29
US20220340646A1 (en) 2022-10-27
TW202041532A (zh) 2020-11-16
EP2857039A4 (en) 2015-08-26
IL235899B (en) 2019-03-31
AR091218A1 (es) 2015-01-21
JP2016147902A (ja) 2016-08-18
JP2018111716A (ja) 2018-07-19
TWI700296B (zh) 2020-08-01
PT2857039T (pt) 2020-01-07
EP3662931B1 (en) 2023-12-06
ES2973070T3 (es) 2024-06-18
LT2857039T (lt) 2020-03-10
ME03587B (me) 2020-07-20
US20150183854A1 (en) 2015-07-02
KR20200029619A (ko) 2020-03-18
BR112014029566A2 (pt) 2017-07-25
MX361128B (es) 2018-11-28
CA2875205A1 (en) 2013-12-05
PH12014502669B1 (en) 2020-02-19
ZA201409186B (en) 2015-12-23
CN104602708B (zh) 2021-11-30
EP2857039A1 (en) 2015-04-08
PL2857039T3 (pl) 2020-05-18
PH12014502669A1 (en) 2015-02-02
CA2875205C (en) 2021-07-20
HRP20192267T1 (hr) 2020-03-20
AU2013268364B2 (en) 2018-02-08
DK2857039T3 (da) 2019-12-16
MX2014014187A (es) 2015-06-04
RS59802B1 (sr) 2020-02-28
JP6406678B2 (ja) 2018-10-17
EP3662931A1 (en) 2020-06-10
SI2857039T1 (sl) 2020-03-31
NZ630536A (en) 2017-03-31
JPWO2013180238A1 (ja) 2016-01-21
AU2018200413B2 (en) 2019-10-17
IL235899A0 (en) 2015-01-29
MY172458A (en) 2019-11-26
TW201410705A (zh) 2014-03-16
AU2018200413A1 (en) 2018-02-08
TWI777183B (zh) 2022-09-11
EP2857039B1 (en) 2019-11-20
WO2013180238A1 (ja) 2013-12-05
CY1122530T1 (el) 2021-01-27
RU2657438C2 (ru) 2018-06-13
KR102208283B1 (ko) 2021-01-26
HUE046919T2 (hu) 2020-04-28
SG10201805410XA (en) 2018-08-30
US20200148753A1 (en) 2020-05-14
ES2763361T3 (es) 2020-05-28
KR102133610B1 (ko) 2020-07-14
JP5971659B2 (ja) 2016-08-17
JP6620829B2 (ja) 2019-12-18
CN104602708A (zh) 2015-05-06
RU2014153099A (ru) 2016-07-20

Similar Documents

Publication Publication Date Title
HK1210031A1 (en) Therapeutic agent or prophylactic agent for dementia
HK1211475A1 (en) Combination therapy
PL3153144T3 (pl) Urządzenie izolacyjne
SG11201501173SA (en) PI3Kδ INHIBITOR
HK1208628A1 (en) Prophylactic or therapeutic agent for hepatic diseases
HK1216297A1 (zh) 腫瘤溶解綜合征的治療藥和預防藥
GB201217439D0 (en) Combination therapy
SG11201500074XA (en) Safety cabinet
HRP20181120T1 (hr) Sanitarni set
PL2554541T3 (pl) Środek terapeutyczny lub środek profilaktyczny na fibromialgię
PL399419A1 (pl) Sposób wytwarzania 4-metoksydihydrochalkonu
PL399418A1 (pl) Sposób wytwarzania 4-metoksydihydrochalkonu
IL236450A (en) Process for making 5-fluoro-h1-pyrazoles
GB201207305D0 (en) Therapy
PL2677104T3 (pl) Szafka bezpieczeństwa
HK1210426A1 (en) Combination therapy
GB2502527B (en) Plumbing apparatus
HK1212895A1 (zh) 用於免疫調節的沙奎那韋-
GB201214234D0 (en) Prophylactic therapy
GB201220253D0 (en) Plumbing apparatus
PL2861904T3 (pl) Ulepszone urządzenie instalacji wodociągowej
GB201211543D0 (en) Combination therapy
PL2677099T3 (pl) Szafka bezpieczeństwa
HU229987B1 (en) Process for the preparation of pyrimidinyl-piperazines
GB201220529D0 (en) No details available