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HK1196289A1 - 用於敗血症的治療和/或改善的藥物 - Google Patents

用於敗血症的治療和/或改善的藥物

Info

Publication number
HK1196289A1
HK1196289A1 HK14109850.4A HK14109850A HK1196289A1 HK 1196289 A1 HK1196289 A1 HK 1196289A1 HK 14109850 A HK14109850 A HK 14109850A HK 1196289 A1 HK1196289 A1 HK 1196289A1
Authority
HK
Hong Kong
Prior art keywords
sepsis
medicine
improvement
treatment
Prior art date
Application number
HK14109850.4A
Other languages
English (en)
Inventor
鶴田壽
青木喜和
大澤寬
．考爾
Original Assignee
旭化成制藥株式會社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 旭化成制藥株式會社 filed Critical 旭化成制藥株式會社
Publication of HK1196289A1 publication Critical patent/HK1196289A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/366—Thrombomodulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/56—Protease inhibitors from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Botany (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
HK14109850.4A 2011-11-15 2014-10-02 用於敗血症的治療和/或改善的藥物 HK1196289A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161559864P 2011-11-15 2011-11-15
PCT/JP2012/079449 WO2013073545A1 (ja) 2011-11-15 2012-11-14 敗血症の治療及び／又は改善のための医薬

Publications (1)

Publication Number Publication Date
HK1196289A1 true HK1196289A1 (zh) 2014-12-12

Family

ID=48429601

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14109850.4A HK1196289A1 (zh) 2011-11-15 2014-10-02 用於敗血症的治療和/或改善的藥物

Country Status (19)

Country Link
US (5) US8772239B2 (zh)
EP (1) EP2781221B9 (zh)
JP (2) JP5902195B2 (zh)
KR (1) KR101672108B1 (zh)
CN (1) CN103974710B (zh)
AU (1) AU2012337838B2 (zh)
BR (1) BR112014011488B1 (zh)
CA (1) CA2854882C (zh)
DK (1) DK2781221T3 (zh)
ES (1) ES2795439T3 (zh)
HK (1) HK1196289A1 (zh)
HU (1) HUE050698T2 (zh)
IL (1) IL232434B (zh)
MX (1) MX354981B (zh)
PL (1) PL2781221T3 (zh)
PT (1) PT2781221T (zh)
RU (1) RU2580756C2 (zh)
WO (1) WO2013073545A1 (zh)
ZA (1) ZA201403494B (zh)

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AU2012337838B2 (en) 2011-11-15 2016-04-21 Asahi Kasei Pharma Corporation Medicament for therapeutic treatment and/or improvement of sepsis
US10126305B2 (en) 2013-06-25 2018-11-13 University of Pittsburg—Of the Commonwealth System of Higher Education Proteomic biomarkers of sepsis in elderly patients
US9730983B2 (en) * 2015-10-02 2017-08-15 Chih-Yuan MA Methods for treatment of CD14-mediated disorders and responses
DK3682247T3 (da) * 2017-09-13 2022-03-21 Brahms Gmbh Proadrenomedullin som markør for unormale blodpladeniveauer
AU2019347406B9 (en) * 2018-09-28 2023-11-16 Asahi Kasei Pharma Corporation Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent
US11497795B2 (en) 2018-09-28 2022-11-15 Asahi Kasei Pharma Corporation Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent
BR112021007460A2 (pt) * 2018-10-22 2021-11-03 Asahi Kasei Pharma Corp Medicamento para tratamento terapêutico e/ou melhora de um paciente com sepse
CN110894494B (zh) * 2019-11-22 2022-09-27 广西梧州制药（集团）股份有限公司 一种大规模高密度悬浮培养293细胞高产腺病毒的方法

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JP2738428B2 (ja) 1987-01-08 1998-04-08 旭化成工業株式会社 トロンビンによるプロテインｃの活性化を促進する作用を有するペプチド
EP0285511B1 (en) 1987-04-01 1992-11-25 Mitsubishi Gas Chemical Company, Inc. Immunoassay of thrombomodulin
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JPS6445398A (en) 1987-08-13 1989-02-17 Kowa Co Antithrombin-binding substance monoclonal antibody, hybridoma producing said antibody and method for purifying and measuring thrombin-binding substance utilizing said monoclonal antibody
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JPH05213998A (ja) 1990-08-03 1993-08-24 Asahi Chem Ind Co Ltd 新規なポリペプチド及びこれを有効成分とする 医薬組成物
KR930008093B1 (ko) 1990-08-03 1993-08-25 아사히가세이고오교 가부시끼가이샤 신규 폴리펩티드 및 이를 유효성분으로 하는 의약조성물
CA2087271C (en) 1990-08-15 2009-03-24 Charles B. Glaser Superior thrombomodulin analogs for pharmaceutical use
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WO2003061687A1 (en) 2002-01-18 2003-07-31 Asahi Kasei Pharma Corporation High-concentration preparation of soluble thrombomodulin
US8293710B2 (en) 2005-01-03 2012-10-23 Blue Blood Biotech Corp. Method for treating wounds using an EGF-like domain of thrombomodulin
WO2008038777A1 (fr) * 2006-09-29 2008-04-03 Asahi Kasei Pharma Corporation Agent thérapeutique pour le syndrome de coagulation intravasculaire disséminée
CA2671863C (en) 2006-12-12 2015-07-21 Eli Lilly And Company Method of treating acute renal failure with thrombomodulin variants
WO2008117735A1 (ja) 2007-03-23 2008-10-02 Asahi Kasei Pharma Corporation 高純度可溶性トロンボモジュリンの製造方法
AR067345A1 (es) 2007-07-10 2009-10-07 Paion Deutschland Gmbh Uso de trombomodulina para la preparacion de un medicamento trombolitico
EP2320936A1 (en) 2008-07-16 2011-05-18 PAION Deutschland GmbH Prevention and treatment of radiation injury
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AU2012337838B2 (en) 2011-11-15 2016-04-21 Asahi Kasei Pharma Corporation Medicament for therapeutic treatment and/or improvement of sepsis
JP6441759B2 (ja) 2015-07-24 2018-12-19 株式会社堀場製作所 分光分析器に用いられる光検出器の出力補正方法

Also Published As

Publication number Publication date
BR112014011488B1 (pt) 2022-07-05
US9592275B2 (en) 2017-03-14
MX2014005895A (es) 2014-06-19
HUE050698T2 (hu) 2020-12-28
PL2781221T3 (pl) 2020-08-24
IL232434B (en) 2018-03-29
US20140296148A1 (en) 2014-10-02
CA2854882C (en) 2016-03-29
US20130244926A1 (en) 2013-09-19
JP2016104803A (ja) 2016-06-09
EP2781221B9 (en) 2020-09-02
CA2854882A1 (en) 2013-05-23
ES2795439T3 (es) 2020-11-23
RU2014124171A (ru) 2015-12-27
BR112014011488A2 (pt) 2017-05-02
CN103974710A (zh) 2014-08-06
US8772239B2 (en) 2014-07-08
ZA201403494B (en) 2016-04-28
PT2781221T (pt) 2020-06-01
WO2013073545A1 (ja) 2013-05-23
EP2781221B1 (en) 2020-04-08
US9034823B2 (en) 2015-05-19
AU2012337838A1 (en) 2014-05-29
KR20140095559A (ko) 2014-08-01
US20160331813A1 (en) 2016-11-17
US20130237482A1 (en) 2013-09-12
KR101672108B1 (ko) 2016-11-02
JP5902195B2 (ja) 2016-04-13
DK2781221T3 (da) 2020-06-02
IL232434A0 (en) 2014-06-30
NZ624542A (en) 2015-06-26
US20150157695A1 (en) 2015-06-11
US9555080B2 (en) 2017-01-31
RU2580756C2 (ru) 2016-04-10
EP2781221A1 (en) 2014-09-24
MX354981B (es) 2018-03-28
AU2012337838B2 (en) 2016-04-21
CN103974710B (zh) 2016-07-06
JPWO2013073545A1 (ja) 2015-04-02
EP2781221A4 (en) 2015-07-15

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