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HK1120793A1 - 4- (ih-indazol-5-yl-amino)-quinazoline compounds as erbb receptor tyrosine kinase inhibitors for the treatment of cancer - Google Patents

4- (ih-indazol-5-yl-amino)-quinazoline compounds as erbb receptor tyrosine kinase inhibitors for the treatment of cancer

Info

Publication number
HK1120793A1
HK1120793A1 HK08112645.6A HK08112645A HK1120793A1 HK 1120793 A1 HK1120793 A1 HK 1120793A1 HK 08112645 A HK08112645 A HK 08112645A HK 1120793 A1 HK1120793 A1 HK 1120793A1
Authority
HK
Hong Kong
Prior art keywords
indazol
cancer
amino
treatment
tyrosine kinase
Prior art date
Application number
HK08112645.6A
Other languages
English (en)
Inventor
Robert Hugh Bradbury
Bernard Christophe Barlaam
Richard Ducray
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of HK1120793A1 publication Critical patent/HK1120793A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK08112645.6A 2005-09-20 2008-11-19 4- (ih-indazol-5-yl-amino)-quinazoline compounds as erbb receptor tyrosine kinase inhibitors for the treatment of cancer HK1120793A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP05291948 2005-09-20
EP05292547 2005-12-02
EP06300343 2006-04-07
PCT/GB2006/003407 WO2007034144A1 (en) 2005-09-20 2006-09-14 4- (ih-indazol-s-yl-amino)-quinazoline compounds as erbb receptor tyrosine kinase inhibitors for the treatment of cancer

Publications (1)

Publication Number Publication Date
HK1120793A1 true HK1120793A1 (en) 2009-04-09

Family

ID=37434116

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08112645.6A HK1120793A1 (en) 2005-09-20 2008-11-19 4- (ih-indazol-5-yl-amino)-quinazoline compounds as erbb receptor tyrosine kinase inhibitors for the treatment of cancer

Country Status (11)

Country Link
US (1) US7820683B2 (xx)
EP (1) EP1928861B1 (xx)
JP (1) JP2009508918A (xx)
AR (1) AR057823A1 (xx)
AT (1) ATE488513T1 (xx)
DE (1) DE602006018331D1 (xx)
ES (1) ES2354457T3 (xx)
HK (1) HK1120793A1 (xx)
TW (1) TW200745090A (xx)
UY (1) UY29801A1 (xx)
WO (1) WO2007034144A1 (xx)

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WO2006064196A1 (en) * 2004-12-14 2006-06-22 Astrazeneca Ab Pyrazolopyrimidine compounds as antitumor agents
JP2012519732A (ja) * 2009-03-09 2012-08-30 サーフェイス ロジックス，インコーポレイティド Ｒｈｏキナーゼ阻害剤
TWI858848B (zh) * 2018-05-08 2024-10-11 大陸商迪哲（江蘇）醫藥股份有限公司 ＥｒｂＢ受體抑制劑
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Also Published As

Publication number Publication date
TW200745090A (en) 2007-12-16
DE602006018331D1 (de) 2010-12-30
AR057823A1 (es) 2007-12-19
EP1928861B1 (en) 2010-11-17
ATE488513T1 (de) 2010-12-15
ES2354457T3 (es) 2011-03-15
US20090048251A1 (en) 2009-02-19
WO2007034144A1 (en) 2007-03-29
JP2009508918A (ja) 2009-03-05
US7820683B2 (en) 2010-10-26
UY29801A1 (es) 2007-04-30
EP1928861A1 (en) 2008-06-11

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