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HK1105536A1 - Triazolopyridinylsulfanyl derivatives as p38 map kinase inhibitors - Google Patents

Triazolopyridinylsulfanyl derivatives as p38 map kinase inhibitors Download PDF

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Publication number
HK1105536A1
HK1105536A1 HK07110750.2A HK07110750A HK1105536A1 HK 1105536 A1 HK1105536 A1 HK 1105536A1 HK 07110750 A HK07110750 A HK 07110750A HK 1105536 A1 HK1105536 A1 HK 1105536A1
Authority
HK
Hong Kong
Prior art keywords
triazolo
pyridin
pyrazol
benzyl
thio
Prior art date
Application number
HK07110750.2A
Other languages
English (en)
Chinese (zh)
Other versions
HK1105536B (en
Inventor
J.P.玛希亚斯
D.S.米兰
R.A.鲁斯外特
C.菲利普斯
Original Assignee
辉瑞大药厂
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0418015A external-priority patent/GB0418015D0/en
Application filed by 辉瑞大药厂 filed Critical 辉瑞大药厂
Publication of HK1105536A1 publication Critical patent/HK1105536A1/xx
Publication of HK1105536B publication Critical patent/HK1105536B/xx

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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  • Animal Behavior & Ethology (AREA)
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  • Hematology (AREA)
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  • Molecular Biology (AREA)
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  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
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  • Pain & Pain Management (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
HK07110750.2A 2004-08-12 2005-08-09 Triazolopyridinylsulfanyl derivatives as p38 map kinase inhibitors HK1105536B (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0418015A GB0418015D0 (en) 2004-08-12 2004-08-12 New compounds
GB0418015.4 2004-08-12
US69155905P 2005-06-17 2005-06-17
US60/691,559 2005-06-17
PCT/IB2005/002574 WO2006018718A2 (en) 2004-08-12 2005-08-09 Triazolopyridinylsulfanyl derivatives as p38 map kinase inhibitors

Publications (2)

Publication Number Publication Date
HK1105536A1 true HK1105536A1 (en) 2008-02-15
HK1105536B HK1105536B (en) 2011-05-06

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Also Published As

Publication number Publication date
MX2007001759A (es) 2007-04-20
CA2576297A1 (en) 2006-02-23
ES2314690T3 (es) 2009-03-16
US7511057B2 (en) 2009-03-31
SI1778686T1 (sl) 2009-02-28
HRP20080608T3 (hr) 2008-12-31
CR8918A (es) 2007-04-02
US20090239899A1 (en) 2009-09-24
DE602005010714D1 (de) 2008-12-11
WO2006018718A3 (en) 2006-05-04
BRPI0514255A (pt) 2008-06-03
NL1029726C2 (nl) 2007-08-14
WO2006018718A2 (en) 2006-02-23
PL1778686T3 (pl) 2009-04-30
NZ552868A (en) 2009-07-31
US8076356B2 (en) 2011-12-13
EA012119B1 (ru) 2009-08-28
ECSP077232A (es) 2007-03-29
CU23497A3 (es) 2010-03-25
GEP20104973B (en) 2010-04-26
DK1778686T3 (da) 2009-01-12
JP4084836B2 (ja) 2008-04-30
EA200700219A1 (ru) 2007-08-31
EP1778686B9 (en) 2009-07-08
MA28798B1 (fr) 2007-08-01
AP2007003905A0 (en) 2007-02-28
NL1029726A1 (nl) 2006-02-14
AU2005273612A1 (en) 2006-02-23
SV2006002193A (es) 2006-03-15
AP2326A (en) 2011-11-24
MY140021A (en) 2009-11-30
IL181047A (en) 2011-06-30
PT1778686E (pt) 2008-12-26
IL181047A0 (en) 2007-07-04
EP1778686B1 (en) 2008-10-29
TNSN07050A1 (fr) 2008-06-02
CY1108788T1 (el) 2014-07-02
AR050692A1 (es) 2006-11-15
NO339320B1 (no) 2016-11-28
GT200500218A (es) 2006-03-21
EP1778686A2 (en) 2007-05-02
HN2005000418A (es) 2009-12-07
AU2005273612B2 (en) 2010-10-14
JP2008509901A (ja) 2008-04-03
US20060035922A1 (en) 2006-02-16
NO20071242L (no) 2007-05-07
CA2576297C (en) 2011-01-25
ATE412652T1 (de) 2008-11-15

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