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HK1059582A1 - 具有電子控制單元的筆式注射器 - Google Patents

具有電子控制單元的筆式注射器 Download PDF

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Publication number
HK1059582A1
HK1059582A1 HK04102496A HK04102496A HK1059582A1 HK 1059582 A1 HK1059582 A1 HK 1059582A1 HK 04102496 A HK04102496 A HK 04102496A HK 04102496 A HK04102496 A HK 04102496A HK 1059582 A1 HK1059582 A1 HK 1059582A1
Authority
HK
Hong Kong
Prior art keywords
medicament
dose
control unit
electronic control
user
Prior art date
Application number
HK04102496A
Other languages
German (de)
English (en)
French (fr)
Other versions
HK1059582B (zh
Inventor
Nigel Langley Christopher
Alistair Day Shane
Frederick Veasey Robert
Woolston Robert
Original Assignee
Sanofi-Aventis Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9905751&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1059582(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi-Aventis Deutschland Gmbh filed Critical Sanofi-Aventis Deutschland Gmbh
Publication of HK1059582A1 publication Critical patent/HK1059582A1/zh
Publication of HK1059582B publication Critical patent/HK1059582B/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14566Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M2005/31588Constructional features or modes of drive mechanisms for piston rods electrically driven
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/21General characteristics of the apparatus insensitive to tilting or inclination, e.g. spill-over prevention
    • A61M2205/215Tilt detection, e.g. for warning or shut-off
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/50General characteristics of the apparatus with microprocessors or computers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/60General characteristics of the apparatus with identification means
    • A61M2205/6018General characteristics of the apparatus with identification means providing set-up signals for the apparatus configuration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/82Internal energy supply devices
    • A61M2205/8206Internal energy supply devices battery-operated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31525Dosing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31546Electrically operated dose setting, e.g. input via touch screen or plus/minus buttons
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00Surgery
    • Y10S128/01Motorized syringe

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Fuel-Injection Apparatus (AREA)
  • Read Only Memory (AREA)
  • External Artificial Organs (AREA)
  • Knitting Machines (AREA)
  • Electrical Control Of Air Or Fuel Supplied To Internal-Combustion Engine (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coating Apparatus (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Polarising Elements (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Elimination Of Static Electricity (AREA)
  • Vehicle Body Suspensions (AREA)
  • Seal Device For Vehicle (AREA)
  • Valve Device For Special Equipments (AREA)
  • Loading And Unloading Of Fuel Tanks Or Ships (AREA)
  • Medicinal Preparation (AREA)
  • Disintegrating Or Milling (AREA)
  • Catching Or Destruction (AREA)
  • Electrostatic Spraying Apparatus (AREA)
HK04102496.1A 2000-12-22 2001-12-21 具有电子控制单元的笔式注射器 HK1059582B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0031466 2000-12-22
GBGB0031466.6A GB0031466D0 (en) 2000-12-22 2000-12-22 Improvements in and relating to an injection device
PCT/GB2001/005747 WO2002058767A1 (en) 2000-12-22 2001-12-21 Pen-type injector having an electronic control unit

Publications (2)

Publication Number Publication Date
HK1059582A1 true HK1059582A1 (zh) 2004-07-09
HK1059582B HK1059582B (zh) 2005-08-05

Family

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Also Published As

Publication number Publication date
ES2240340T3 (es) 2005-10-16
KR100826220B1 (ko) 2008-04-30
ES2240344T3 (es) 2005-10-16
ES2272411T3 (es) 2007-05-01
DE60110638T2 (de) 2006-01-19
BR0116277B1 (pt) 2010-09-21
MXPA03005577A (es) 2004-05-17
IL156247A0 (en) 2004-01-04
BR0116297B1 (pt) 2010-10-19
JP4308525B2 (ja) 2009-08-05
JP5461368B2 (ja) 2014-04-02
KR20030066727A (ko) 2003-08-09
DK1349587T3 (da) 2005-08-29
US8926553B2 (en) 2015-01-06
US8128603B2 (en) 2012-03-06
BR0116296A (pt) 2004-08-17
DK1353713T3 (da) 2006-08-28
EP1351728B1 (en) 2005-04-27
KR100826218B1 (ko) 2008-04-30
PT1349587E (pt) 2005-08-31
EP1349587B1 (en) 2005-05-04
DE60110637T2 (de) 2006-01-19
EP1353713B1 (en) 2006-04-26
DE60110636T2 (de) 2006-01-19
WO2002051478A1 (en) 2002-07-04
US20040054318A1 (en) 2004-03-18
JP4676674B2 (ja) 2011-04-27
EP1353712A1 (en) 2003-10-22
ES2241745T3 (es) 2005-11-01
CN1290589C (zh) 2006-12-20
CA2430914C (en) 2010-02-23
ATE300967T1 (de) 2005-08-15
ATE356644T1 (de) 2007-04-15
KR100788314B1 (ko) 2007-12-27
PT1349593E (pt) 2007-06-15
AU2002216256B2 (en) 2005-08-04
DE60112472D1 (de) 2005-09-08
JP4287148B2 (ja) 2009-07-01
US20040049156A1 (en) 2004-03-11
DK1351728T3 (da) 2005-08-22
KR20030066740A (ko) 2003-08-09
BR0116297A (pt) 2004-08-17
ATE324131T1 (de) 2006-05-15
DE60112472T3 (de) 2016-08-11
AU2002216236B2 (en) 2005-08-04
CN1482927A (zh) 2004-03-17
KR100788318B1 (ko) 2007-12-27
CA2430928A1 (en) 2002-07-04
CA2430922C (en) 2010-02-02
ES2240341T3 (es) 2005-10-16
US6997906B2 (en) 2006-02-14
WO2002051472A1 (en) 2002-07-04
CN100400117C (zh) 2008-07-09
KR20030066738A (ko) 2003-08-09
WO2002051475A1 (en) 2002-07-04
DE60110642D1 (de) 2005-06-09
ATE294601T1 (de) 2005-05-15
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KR100826221B1 (ko) 2008-04-30
DE60112472T2 (de) 2006-08-17
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JP4694095B2 (ja) 2011-06-01
CA2430931A1 (en) 2002-07-04
EP1349594B1 (en) 2005-05-04
EP1353712B1 (en) 2006-10-11
IL156270A0 (en) 2004-01-04
WO2002051476A1 (en) 2002-07-04
CN1481262A (zh) 2004-03-10
HK1059579A1 (zh) 2004-07-09
KR20030066739A (ko) 2003-08-09
CY1106295T1 (el) 2011-10-12
CN1505534A (zh) 2004-06-16
HK1059902A1 (zh) 2004-07-23
US6869413B2 (en) 2005-03-22
DE60119164D1 (de) 2006-06-01
DK1349591T4 (en) 2016-05-30
JP2004516107A (ja) 2004-06-03
CA2430940A1 (en) 2002-07-04
JP4308524B2 (ja) 2009-08-05
CN1292809C (zh) 2007-01-03
CN1290588C (zh) 2006-12-20
DE60110639T2 (de) 2006-01-19
KR20030066728A (ko) 2003-08-09
PT1349591E (pt) 2005-11-30
JP2011062538A (ja) 2011-03-31
EP1349591A1 (en) 2003-10-08
EP1349593A1 (en) 2003-10-08
BR0116280B1 (pt) 2009-12-01
US6969370B2 (en) 2005-11-29
DK1349591T3 (da) 2005-11-28
EP1349587A1 (en) 2003-10-08
AU2007201951A1 (en) 2007-05-24
DK1349593T3 (da) 2007-07-16
ES2240343T3 (es) 2005-10-16
US20040030296A1 (en) 2004-02-12
CA2430914A1 (en) 2002-08-01
JP5054739B2 (ja) 2012-10-24
JP2004516106A (ja) 2004-06-03
BR0116295A (pt) 2004-08-17
CA2430788A1 (en) 2002-07-04
AU2007201951B2 (en) 2009-07-16
KR100788319B1 (ko) 2007-12-27
EP1349593B1 (en) 2007-03-14
IL156244A (en) 2009-05-04
JP2004516109A (ja) 2004-06-03
ATE294603T1 (de) 2005-05-15
AU2002216230B2 (en) 2005-08-04
GB0031466D0 (en) 2001-02-07
JP2004516111A (ja) 2004-06-03
DE60110929T2 (de) 2006-04-27
EP1351728A1 (en) 2003-10-15
PT1349594E (pt) 2005-08-31
US20040073173A1 (en) 2004-04-15
DE60110463T2 (de) 2006-02-23
CN1482926A (zh) 2004-03-17
IL156251A (en) 2009-02-11
KR100826227B1 (ko) 2008-04-30
BR0116295B1 (pt) 2009-12-01
JP4308523B2 (ja) 2009-08-05
IL156239A0 (en) 2004-01-04
EP1349592B1 (en) 2005-05-04
KR100826222B1 (ko) 2008-04-30
MXPA03005596A (es) 2004-05-17
BR0116294A (pt) 2004-08-17
DE60127303D1 (de) 2007-04-26
JP2004516105A (ja) 2004-06-03
CA2430940C (en) 2009-11-24
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KR100788321B1 (ko) 2007-12-27
JP4436043B2 (ja) 2010-03-24
JP4955637B2 (ja) 2012-06-20
AU2002222302B2 (en) 2005-08-04
US6949082B2 (en) 2005-09-27
DE60119164T2 (de) 2007-02-01
JP2004516108A (ja) 2004-06-03
EP1349588B1 (en) 2005-05-18
MXPA03005592A (es) 2004-05-14
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HK1059586A1 (zh) 2004-07-09
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KR100788316B1 (ko) 2007-12-27
US7052484B2 (en) 2006-05-30
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WO2002051480A1 (en) 2002-07-04
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CY1106652T1 (el) 2012-01-25
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WO2002051477A1 (en) 2002-07-04
AU2002216254B2 (en) 2007-01-25
CA2430920A1 (en) 2002-07-04
BR0116278B1 (pt) 2010-09-21
CN1501821A (zh) 2004-06-02
HK1059903A1 (zh) 2004-07-23
JP2010005414A (ja) 2010-01-14
EP1345641A1 (en) 2003-09-24
CA2430920C (en) 2009-04-07
DK1349588T3 (da) 2005-09-05
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JP4164362B2 (ja) 2008-10-15
JP2004523282A (ja) 2004-08-05
ATE294600T1 (de) 2005-05-15
ATE294602T1 (de) 2005-05-15
PT1349588E (pt) 2005-09-30
CN1481261A (zh) 2004-03-10
MXPA03005576A (es) 2004-05-05
PT1349592E (pt) 2005-08-31
JP2009000557A (ja) 2009-01-08
EP1349592A1 (en) 2003-10-08
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AU2002216232B2 (en) 2005-08-18
JP2004516103A (ja) 2004-06-03
US20040054329A1 (en) 2004-03-18
US7699815B2 (en) 2010-04-20
EP1349591B8 (en) 2005-12-28
JP4287145B2 (ja) 2009-07-01
US20040030298A1 (en) 2004-02-12
PT1353713E (pt) 2006-08-31
ATE294002T1 (de) 2005-05-15
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US6942646B2 (en) 2005-09-13
IL156245A0 (en) 2004-01-04
EP1349596B1 (en) 2005-05-04
EP1349596A1 (en) 2003-10-08
IL156248A0 (en) 2004-01-04
HK1059747A1 (zh) 2004-07-16
JP4676673B2 (ja) 2011-04-27
BR0116274B1 (pt) 2009-12-01
IL156239A (en) 2008-11-26
DK1349595T3 (da) 2005-11-21
BR0116279B1 (pt) 2009-12-01
WO2002051471A1 (en) 2002-07-04
DE60110637D1 (de) 2005-06-09
US20040078001A1 (en) 2004-04-22
DE60127303T2 (de) 2007-12-20
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ES2246289T3 (es) 2006-02-16
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HK1059584A1 (zh) 2004-07-09
AU2002217283B2 (en) 2007-01-25
JP2004516102A (ja) 2004-06-03
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CA2430788C (en) 2010-02-02
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AU2002216231B2 (en) 2005-08-04
PT1349596E (pt) 2005-08-31
MXPA03005595A (es) 2004-05-17
EP1353715B1 (en) 2005-05-04
DK1349593T4 (en) 2018-06-25
KR20030066724A (ko) 2003-08-09
PT1353715E (pt) 2005-08-31
MXPA03005584A (es) 2004-05-17
AU2007202032B2 (en) 2009-11-05
ES2240342T3 (es) 2005-10-16
HK1059581A1 (zh) 2004-07-09
CN1284609C (zh) 2006-11-15
WO2002058766A1 (en) 2002-08-01
DK1353715T3 (da) 2005-08-22
CN1267161C (zh) 2006-08-02
IL156238A (en) 2009-02-11
KR100788323B1 (ko) 2007-12-27
CN1270786C (zh) 2006-08-23
IL156241A0 (en) 2004-01-04
US20040054328A1 (en) 2004-03-18
KR20030066725A (ko) 2003-08-09
EP1349595B1 (en) 2005-07-27
BR0116298A (pt) 2004-08-17
IL156243A0 (en) 2004-01-04
ES2247008T3 (es) 2006-03-01
CN1261171C (zh) 2006-06-28
CA2430938C (en) 2009-11-24
PT1351728E (pt) 2005-08-31
CA2430931C (en) 2010-02-02
US8469922B2 (en) 2013-06-25
KR20030066729A (ko) 2003-08-09
PT1353712E (pt) 2007-01-31
EP1349591B2 (en) 2016-03-09
CN1482928A (zh) 2004-03-17
DE60110463D1 (de) 2005-06-02
DE60110642T2 (de) 2006-01-19
CA2430925A1 (en) 2002-07-04
IL156251A0 (en) 2004-01-04
DE60110638D1 (de) 2005-06-09
IL156244A0 (en) 2004-01-04
JP2004516110A (ja) 2004-06-03
CN1482930A (zh) 2004-03-17
EP1349593B2 (en) 2018-04-04
BR0116280A (pt) 2003-12-30
EP1349588A1 (en) 2003-10-08
CA2430938A1 (en) 2002-07-04
CN1292807C (zh) 2007-01-03
BR0116274A (pt) 2003-12-30
IL156240A (en) 2007-12-03
CN1290587C (zh) 2006-12-20
MXPA03005575A (es) 2004-05-05
DE60112326D1 (de) 2005-09-01
DK1349594T3 (da) 2005-08-29
BR0116275A (pt) 2003-12-30
HK1059583A1 (zh) 2004-07-09
DE60110636D1 (de) 2005-06-09
US20040097873A1 (en) 2004-05-20
CA2430942C (en) 2010-02-02
CY1106128T1 (el) 2011-06-08
CA2431135C (en) 2009-11-24
MXPA03005590A (es) 2004-05-14
IL156245A (en) 2007-12-03
US20040044317A1 (en) 2004-03-04
WO2002051473A1 (en) 2002-07-04
MXPA03005593A (es) 2004-05-17
EP1353715A1 (en) 2003-10-22
DE60127303T3 (de) 2018-08-16
JP4150589B2 (ja) 2008-09-17
DE60112326T2 (de) 2006-04-20
HK1059904A1 (zh) 2004-07-23
CA2430928C (en) 2010-11-30
WO2002051479A1 (en) 2002-07-04
BR0116279A (pt) 2003-12-30
DK1349596T3 (da) 2005-08-22
US20040054319A1 (en) 2004-03-18
US20040024364A1 (en) 2004-02-05
DK1353712T3 (da) 2007-02-12
JP2004516112A (ja) 2004-06-03
BR0116273B1 (pt) 2009-12-01
EP1349591B1 (en) 2005-08-03
ATE300324T1 (de) 2005-08-15
CA2430917A1 (en) 2002-07-04
BR0116296B1 (pt) 2009-12-01
MXPA03005591A (es) 2004-05-14
DE60123836D1 (de) 2006-11-23
DE60123836T2 (de) 2007-05-24
IL156238A0 (en) 2004-01-04
IL156243A (en) 2008-11-03
AU2002216235B2 (en) 2007-05-24
IL156242A0 (en) 2004-01-04
DK1349592T3 (da) 2005-08-29
CN1482931A (zh) 2004-03-17
ES2283375T3 (es) 2007-11-01
HK1059585A1 (zh) 2004-07-09
IL156270A (en) 2009-02-11
CN1482933A (zh) 2004-03-17
US20040122355A1 (en) 2004-06-24
ATE342076T1 (de) 2006-11-15
BR0116275B1 (pt) 2010-09-21
KR20030066726A (ko) 2003-08-09
HK1059580A1 (zh) 2004-07-09
CA2431135A1 (en) 2002-07-04
WO2002051474A1 (en) 2002-07-04
BR0116278A (pt) 2003-12-30
AU2007202032A1 (en) 2007-05-24
CN1482929A (zh) 2004-03-17
ES2247008T5 (es) 2016-06-24
DE60110929D1 (de) 2005-06-23
KR20030066743A (ko) 2003-08-09
PT1349595E (pt) 2005-11-30
CN1482932A (zh) 2004-03-17
CA2430935A1 (en) 2002-07-04
ATE295749T1 (de) 2005-06-15
BR0116273A (pt) 2003-12-30
DE60110639D1 (de) 2005-06-09
MXPA03005589A (es) 2004-05-14
KR20030066741A (ko) 2003-08-09
US7081108B2 (en) 2006-07-25
CA2430942A1 (en) 2002-08-01
CN1248746C (zh) 2006-04-05
IL156246A0 (en) 2004-01-04
EP1353713A1 (en) 2003-10-22
EP1349595A1 (en) 2003-10-08
CN1325127C (zh) 2007-07-11

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