HK1021860A1 - Process for preparing polymer coated tablet comprising amoxycllin and clavunalate, coated with an aqueous polymeric filmcoating - Google Patents

Process for preparing polymer coated tablet comprising amoxycllin and clavunalate, coated with an aqueous polymeric filmcoating

Info

Publication number: HK1021860A1
Authority: HK; Hong Kong
Prior art keywords: coated; clavunalate; amoxycllin; filmcoating; preparing polymer
Prior art date: 1994-04-23

Application number

HK99105804A

Other languages

English (en)

Inventor

Creighton Pierce Conley

Nigel Philip Davidson

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-04-23

Filing date

1998-09-21

Publication date

2000-07-07

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10754044&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1021860(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-09-21 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

2000-07-07 Publication of HK1021860A1 publication Critical patent/HK1021860A1/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

HK99105804A 1994-04-23 1998-09-21 Process for preparing polymer coated tablet comprising amoxycllin and clavunalate, coated with an aqueous polymeric filmcoating HK1021860A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB9408117A GB9408117D0 (en)	1994-04-23	1994-04-23	Pharmaceutical formulations

Publications (1)

Publication Number	Publication Date
HK1021860A1 true HK1021860A1 (en)	2000-07-07

Family

ID=10754044

Family Applications (5)

Application Number	Title	Priority Date	Filing Date
HK99105804A HK1021860A1 (en)	1994-04-23	1998-09-21	Process for preparing polymer coated tablet comprising amoxycllin and clavunalate, coated with an aqueous polymeric filmcoating
HK01107178A HK1036404A1 (en)	1994-04-23	1998-09-21	Process for preparing polymer coated tablet comprising amoxycillin and clavunalate, coated with an aqueous polymeric filmcoating
HK03101681.9A HK1050992A1 (zh)	1994-04-23	1998-09-21	含有藥物配方的阿莫西林和克拉維酸
HK00104976A HK1027024A1 (en)	1994-04-23	1998-09-21	Polymer coated tablet comprising amoxycillin and clavunalate
HK98110787A HK1009936A1 (en)	1994-04-23	1998-09-21	Polymer coated tablet comprising amoxycillin and clavulanate

Family Applications After (4)

Application Number	Title	Priority Date	Filing Date
HK01107178A HK1036404A1 (en)	1994-04-23	1998-09-21	Process for preparing polymer coated tablet comprising amoxycillin and clavunalate, coated with an aqueous polymeric filmcoating
HK03101681.9A HK1050992A1 (zh)	1994-04-23	1998-09-21	含有藥物配方的阿莫西林和克拉維酸
HK00104976A HK1027024A1 (en)	1994-04-23	1998-09-21	Polymer coated tablet comprising amoxycillin and clavunalate
HK98110787A HK1009936A1 (en)	1994-04-23	1998-09-21	Polymer coated tablet comprising amoxycillin and clavulanate

Country Status (35)

Country	Link
US (1)	US6051255A (zh)
EP (5)	EP0758235B1 (zh)
JP (1)	JP3622975B2 (zh)
CN (1)	CN1134258C (zh)
AP (2)	AP564A (zh)
AT (6)	ATE223706T1 (zh)
AU (1)	AU684949B2 (zh)
BG (1)	BG62842B1 (zh)
BR (1)	BR9507502A (zh)
CA (1)	CA2188496A1 (zh)
CZ (2)	CZ11376U1 (zh)
DE (5)	DE69528204T2 (zh)
DK (4)	DK1093813T3 (zh)
DZ (1)	DZ1876A1 (zh)
ES (4)	ES2182754T3 (zh)
FI (1)	FI964249A0 (zh)
GB (1)	GB9408117D0 (zh)
GR (2)	GR3035031T3 (zh)
HK (5)	HK1021860A1 (zh)
HU (1)	HU228399B1 (zh)
IL (1)	IL113433A (zh)
MA (1)	MA23528A1 (zh)
MY (1)	MY115351A (zh)
NO (1)	NO310703B1 (zh)
NZ (1)	NZ285080A (zh)
OA (1)	OA10377A (zh)
PL (1)	PL316966A1 (zh)
PT (4)	PT758235E (zh)
RO (1)	RO116997B1 (zh)
RU (1)	RU2152213C1 (zh)
SA (1)	SA95160343B1 (zh)
SI (1)	SI0758235T1 (zh)
SK (1)	SK282594B6 (zh)
WO (1)	WO1995028927A1 (zh)
ZA (1)	ZA953236B (zh)

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GB9407386D0 (en)	1994-04-14	1994-06-08	Smithkline Beecham Plc	Pharmaceutical formulation
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DZ2028A1 (fr) *	1995-05-03	2002-10-23	Smithkline Beecham Plc	Médicaments destinés au traitement d'infections bactériennes en pédiatrie.
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IL123563A (en) *	1995-09-07	2002-02-10	Smithkline Beecham Corp	Pharmaceutical formulations comprising amoxycillin and clavulanate in a weight ratio between 14:1 and 16:1 inclusive
AT407701B (de) *	1996-08-12	2001-05-25	Biochemie Gmbh	Zur direkttablettierung geeignete mischung, die als wesentliche komponenten amoxicillin-trihydrat und das kaliumsalz der clavulansäure enthält und verfahren zur herstellung dieser mischung
TWI225402B (en)	1996-03-13	2004-12-21	Biochemie Gmbh	Auxiliary-free agglomerates
GB9613470D0 (en)	1996-06-27	1996-08-28	Ciba Geigy Ag	Small solid oral dosage form
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GB9617780D0 (en) *	1996-08-24	1996-10-02	Smithkline Beecham Plc	Method of treatment
AU6496498A (en) *	1997-02-07	1998-08-26	Gist-Brocades B.V.	Homogeneous granulated formulations for dose sipping technology
EA002595B1 (ru) *	1997-02-14	2002-06-27	Смитклайн Бичем Лаборатуар Фармасетик	Фармацевтический препарат, содержащий амоксициллин и клавуланат, способ его приготовления и гранулят, содержащий амоксициллин и клавуланат
US20030124187A1 (en) *	1997-02-14	2003-07-03	Smithkline Beecham Laboratoires Pharmaceutiques,	Pharmaceutical formulations comprising amoxycillin and clavulanate
EP1023065A1 (en) *	1997-08-29	2000-08-02	Dsm N.V.	Granules free of excipients
AU747099B2 (en)	1997-10-31	2002-05-09	Pharmacia Corporation	Gellan gum tablet coating
MXPA01009808A (es)	1999-04-01	2002-04-24	Dsm Nv	Aglomerados por cristalizacion.
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US7250176B1 (en) *	1999-04-13	2007-07-31	Beecham Pharmaceuticals (Pte) Limited	Method of treating a bacterial infection
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US6544555B2 (en)	2000-02-24	2003-04-08	Advancis Pharmaceutical Corp.	Antibiotic product, use and formulation thereof
WO2002002081A1 (en) *	2000-07-05	2002-01-10	Capricorn Pharma, Inc.	Rapid-melt semi-solid compositions, methods of making same and methods of using same
US6375982B1 (en) *	2000-07-05	2002-04-23	Capricorn Pharma, Inc.	Rapid-melt semi-solid compositions, methods of making same and method of using same
EP1330236A2 (en) *	2000-10-12	2003-07-30	Beecham Pharmaceuticals (Pte) Limited	Formulation containing amoxicillin
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US6541014B2 (en) *	2000-10-13	2003-04-01	Advancis Pharmaceutical Corp.	Antiviral product, use and formulation thereof
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AU2003210925A1 (en) *	2002-02-07	2003-09-02	Rutgers, The State University	Antibiotic polymers
KR100967782B1 (ko) *	2002-02-14	2010-07-05	글락소 그룹 리미티드	Ｎ-((1-Ｎ-부틸-4-피페리디닐)메틸)-3,4-디하이드로-2Ｈ-(1,3)옥사지노(3,2-ａ)인돌-10-카복스아미드 또는 그의 염을포함하는 제약 조성물, 및 건식 과립화를 포함하는 그의제조 방법
GB0203528D0 (en) *	2002-02-14	2002-04-03	Glaxo Group Ltd	Process and composition
US8637512B2 (en)	2002-07-29	2014-01-28	Glaxo Group Limited	Formulations and method of treatment
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US7429619B2 (en) *	2002-08-02	2008-09-30	Mcneil Consumer Healthcare	Polyacrylic film forming compositions
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JP5000491B2 (ja)	2005-05-20	2012-08-15	第一三共株式会社	フィルムコーティング製剤
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SI2477611T1 (sl) *	2009-09-18	2017-07-31	Sanofi	Formulacije tablete (Z)-2-ciano-3-hidroksi-but-2-enojska kislina-(4'-trifluormetilfenil)-amida z izboljšano stabilnostjo
TR200909787A2 (tr)	2009-12-25	2011-07-21	Bi̇lgi̇ç Mahmut	Üçüncü kuşak bir sefalosporin ve klavulanik asit içeren farmasötik formülasyonlar.
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TR201000686A1 (tr)	2010-01-29	2011-08-22	B�Lg�� Mahmut	Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@
TR201000688A2 (tr)	2010-01-29	2011-08-22	B�Lg�� Mahmut	Aktif madde olarak sefaklor ve klavulanik asit içeren efervesan formülasyonlar.
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GB1241844A (en)	1968-08-23	1971-08-04	Beecham Group Ltd	Penicillins
GB1508977A (en)	1974-04-20	1978-04-26	Beecham Group Ltd	Beta-lactam antibiotic from streptomyces clavuligerus
US4098897A (en) *	1975-04-14	1978-07-04	Beecham Group Limited	Anti bacterial agents
JO984B1 (en) *	1977-10-11	1979-12-01	بيتشام غروب ليمتد	A dry pharmaceutical compound with a suitable dosage unit for oral administration
NZ198241A (en) *	1980-09-27	1983-12-16	Beecham Group Ltd	Tablet containing amoxycillin and potassium clavulanate
EP0080862B1 (en) *	1981-12-02	1985-09-25	Beecham Group Plc	Pharmaceutical formulation comprising beta-lactam antibiotics
GB9408117D0 (en) *	1994-04-23	1994-06-15	Smithkline Beecham Corp	Pharmaceutical formulations
IE20000271A1 (en) *	1999-04-13	2001-04-04	Beecham Pharm Pte Ltd	Pharmaceutical Formulations of Amoxycillin and Potassium Clavulanate
EP1330236A2 (en) *	2000-10-12	2003-07-30	Beecham Pharmaceuticals (Pte) Limited	Formulation containing amoxicillin

1994
- 1994-04-23 GB GB9408117A patent/GB9408117D0/en active Pending
1995
- 1995-04-13 AP APAP/P/1995/000733A patent/AP564A/en active
- 1995-04-19 CZ CZ200011418U patent/CZ11376U1/cs not_active IP Right Cessation
- 1995-04-19 EP EP95917937A patent/EP0758235B1/en not_active Expired - Lifetime
- 1995-04-19 RU RU96122474/14A patent/RU2152213C1/ru active
- 1995-04-19 DK DK00204182T patent/DK1093813T3/da active
- 1995-04-19 ES ES00204182T patent/ES2182754T3/es not_active Expired - Lifetime
- 1995-04-19 ES ES95917937T patent/ES2161288T3/es not_active Expired - Lifetime
- 1995-04-19 DE DE69528204T patent/DE69528204T2/de not_active Expired - Lifetime
- 1995-04-19 NZ NZ285080A patent/NZ285080A/en not_active IP Right Cessation
- 1995-04-19 AT AT99200891T patent/ATE223706T1/de active
- 1995-04-19 SI SI9530526T patent/SI0758235T1/xx unknown
- 1995-04-19 RO RO96-02030A patent/RO116997B1/ro unknown
- 1995-04-19 EP EP99200891A patent/EP0978276B1/en not_active Expired - Lifetime
- 1995-04-19 US US08/727,581 patent/US6051255A/en not_active Expired - Lifetime
- 1995-04-19 ES ES96202848T patent/ES2152485T3/es not_active Expired - Lifetime
- 1995-04-19 CZ CZ19963090A patent/CZ294168B6/cs not_active IP Right Cessation
- 1995-04-19 PT PT95917937T patent/PT758235E/pt unknown
- 1995-04-19 CN CNB951934023A patent/CN1134258C/zh not_active Expired - Lifetime
- 1995-04-19 EP EP96202848A patent/EP0761218B1/en not_active Revoked
- 1995-04-19 PT PT00204182T patent/PT1093813E/pt unknown
- 1995-04-19 EP EP02076874A patent/EP1243267A3/en not_active Withdrawn
- 1995-04-19 AT AT95917937T patent/ATE203161T1/de active
- 1995-04-19 DE DE69519093T patent/DE69519093T2/de not_active Expired - Fee Related
- 1995-04-19 EP EP00204182A patent/EP1093813B1/en not_active Revoked
- 1995-04-19 AU AU24068/95A patent/AU684949B2/en not_active Expired
- 1995-04-19 DE DE69528608T patent/DE69528608T2/de not_active Revoked
- 1995-04-19 PT PT99200891T patent/PT978276E/pt unknown
- 1995-04-19 PT PT96202848T patent/PT761218E/pt unknown
- 1995-04-19 SK SK1354-96A patent/SK282594B6/sk not_active IP Right Cessation
- 1995-04-19 WO PCT/EP1995/001463 patent/WO1995028927A1/en active IP Right Grant
- 1995-04-19 CA CA002188496A patent/CA2188496A1/en not_active Abandoned
- 1995-04-19 AT AT96202848T patent/ATE196845T1/de not_active IP Right Cessation
- 1995-04-19 DK DK96202848T patent/DK0761218T3/da active
- 1995-04-19 DE DE69521799T patent/DE69521799T2/de not_active Expired - Lifetime
- 1995-04-19 DE DE29522153U patent/DE29522153U1/de not_active Expired - Lifetime
- 1995-04-19 AP APAP/P/1996/000868A patent/AP9600868A0/en unknown
- 1995-04-19 ES ES99200891T patent/ES2180251T3/es not_active Expired - Lifetime
- 1995-04-19 PL PL95316966A patent/PL316966A1/xx unknown
- 1995-04-19 DK DK95917937T patent/DK0758235T3/da active
- 1995-04-19 DK DK99200891T patent/DK0978276T3/da active
- 1995-04-19 BR BR9507502A patent/BR9507502A/pt not_active IP Right Cessation
- 1995-04-19 AT AT00204182T patent/ATE226074T1/de not_active IP Right Cessation
- 1995-04-19 JP JP52733495A patent/JP3622975B2/ja not_active Expired - Lifetime
- 1995-04-19 HU HU9602922A patent/HU228399B1/hu unknown
- 1995-04-20 IL IL11343395A patent/IL113433A/xx unknown
- 1995-04-20 MY MYPI95001037A patent/MY115351A/en unknown
- 1995-04-21 ZA ZA953236A patent/ZA953236B/xx unknown
- 1995-04-21 MA MA23858A patent/MA23528A1/fr unknown
- 1995-04-22 DZ DZ950044A patent/DZ1876A1/fr active
- 1995-10-25 SA SA95160343A patent/SA95160343B1/ar unknown
1996
- 1996-10-22 NO NO19964488A patent/NO310703B1/no not_active IP Right Cessation
- 1996-10-22 FI FI964249A patent/FI964249A0/fi not_active Application Discontinuation
- 1996-10-23 BG BG100933A patent/BG62842B1/bg unknown
- 1996-10-23 OA OA60908A patent/OA10377A/en unknown
1998
- 1998-09-21 HK HK99105804A patent/HK1021860A1/xx not_active IP Right Cessation
- 1998-09-21 HK HK01107178A patent/HK1036404A1/xx not_active IP Right Cessation
- 1998-09-21 HK HK03101681.9A patent/HK1050992A1/zh unknown
- 1998-09-21 HK HK00104976A patent/HK1027024A1/xx not_active IP Right Cessation
- 1998-09-21 HK HK98110787A patent/HK1009936A1/xx not_active IP Right Cessation
2000
- 2000-07-18 AT AT0052400U patent/AT5349U1/de not_active IP Right Cessation
- 2000-12-12 GR GR20000402718T patent/GR3035031T3/el not_active IP Right Cessation
2001
- 2001-04-11 AT AT0028501U patent/AT5350U1/de not_active IP Right Cessation
- 2001-10-09 GR GR20010401708T patent/GR3036844T3/el unknown

Also Published As

Publication number	Publication date
HK1027024A1 (en)	2001-01-05
EP1093813B1 (en)	2002-10-16
WO1995028927A1 (en)	1995-11-02
ES2180251T3 (es)	2003-02-01
AP9600868A0 (en)	1996-10-31
DE69521799T2 (de)	2002-06-13
ZA953236B (en)	1995-12-27
PT761218E (pt)	2001-03-30
RU2152213C1 (ru)	2000-07-10
ATE226074T1 (de)	2002-11-15
IL113433A (en)	2003-06-24
DE69528204D1 (de)	2002-10-17
PT978276E (pt)	2003-01-31
DK0978276T3 (da)	2003-01-20
AU2406895A (en)	1995-11-16
AT5350U1 (de)	2002-06-25
EP1243267A2 (en)	2002-09-25
BG62842B1 (bg)	2000-09-29
HUT76335A (en)	1997-08-28
DZ1876A1 (fr)	2002-02-17
DE29522153U1 (de)	2000-04-06
AU684949B2 (en)	1998-01-08
EP0978276A3 (en)	2000-04-12
EP1093813A3 (en)	2001-05-30
BR9507502A (pt)	1997-09-02
ATE203161T1 (de)	2001-08-15
CZ294168B6 (cs)	2004-10-13
FI964249L (fi)	1996-10-22
SI0758235T1 (en)	2001-10-31
NZ285080A (en)	1998-05-27
NO310703B1 (no)	2001-08-20
HU9602922D0 (en)	1996-12-30
JP3622975B2 (ja)	2005-02-23
HK1050992A1 (zh)	2003-07-18
EP1093813A2 (en)	2001-04-25
EP0761218B1 (en)	2000-10-11
DE69521799D1 (de)	2001-08-23
CN1134258C (zh)	2004-01-14
AT5349U1 (de)	2002-06-25
SA95160343B1 (ar)	2005-05-04
ATE196845T1 (de)	2000-10-15
PL316966A1 (en)	1997-03-03
HK1009936A1 (en)	1999-06-11
EP0978276B1 (en)	2002-09-11
FI964249A0 (fi)	1996-10-22
DE69528608T2 (de)	2003-06-26
US6051255A (en)	2000-04-18
AP9500733A0 (en)	1995-04-30
PT1093813E (pt)	2003-02-28
AP564A (en)	1996-11-21
SK282594B6 (sk)	2002-10-08
IL113433A0 (en)	1995-07-31
CZ11376U1 (cs)	2001-07-12
DE69519093T2 (de)	2001-07-19
ES2152485T3 (es)	2001-02-01
EP0758235A1 (en)	1997-02-19
ES2161288T3 (es)	2001-12-01
HU228399B1 (en)	2013-03-28
DK0758235T3 (da)	2001-10-29
HK1036404A1 (en)	2002-01-04
CN1149829A (zh)	1997-05-14
OA10377A (en)	2001-11-21
DK0761218T3 (da)	2000-12-18
EP0761218A1 (en)	1997-03-12
BG100933A (en)	1997-07-31
GR3036844T3 (en)	2002-01-31
EP1243267A3 (en)	2002-10-30
CZ309096A3 (en)	1997-04-16
JPH09512027A (ja)	1997-12-02
DE69528608D1 (de)	2002-11-21
MA23528A1 (fr)	1995-12-31
PT758235E (pt)	2001-10-31
DE69528204T2 (de)	2003-08-07
NO964488L (no)	1996-12-17
DE69519093D1 (de)	2000-11-16
SK135496A3 (en)	1997-05-07
EP0758235B1 (en)	2001-07-18
ES2182754T3 (es)	2003-03-16
GR3035031T3 (en)	2001-03-30
EP0978276A2 (en)	2000-02-09
DK1093813T3 (da)	2003-02-17
CA2188496A1 (en)	1995-11-02
ATE223706T1 (de)	2002-09-15
MY115351A (en)	2003-05-31
GB9408117D0 (en)	1994-06-15
RO116997B1 (ro)	2001-09-28
NO964488D0 (no)	1996-10-22

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Legal Events

Date	Code	Title	Description
2004-12-15	PF	Patent in force
2015-05-08	PE	Patent expired	Effective date: 20150418