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HK1019555A1 - Effervescent bisphosphonate formulation - Google Patents

Effervescent bisphosphonate formulation Download PDF

Info

Publication number
HK1019555A1
HK1019555A1 HK99104703A HK99104703A HK1019555A1 HK 1019555 A1 HK1019555 A1 HK 1019555A1 HK 99104703 A HK99104703 A HK 99104703A HK 99104703 A HK99104703 A HK 99104703A HK 1019555 A1 HK1019555 A1 HK 1019555A1
Authority
HK
Hong Kong
Prior art keywords
alendronate
sodium
carbonate
formulation
phosphonate
Prior art date
Application number
HK99104703A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1019555B (en
Inventor
V. Katdare Ashok
A. Kramer Kenneth
R. Gardner Colin
Original Assignee
Merck Sharp & Dohme Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9613183.4A external-priority patent/GB9613183D0/en
Application filed by Merck Sharp & Dohme Corp. filed Critical Merck Sharp & Dohme Corp.
Publication of HK1019555A1 publication Critical patent/HK1019555A1/en
Publication of HK1019555B publication Critical patent/HK1019555B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007Effervescent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
HK99104703.2A 1996-05-17 1997-05-13 Effervescent bisphosphonate formulation HK1019555B (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1788196P 1996-05-17 1996-05-17
US17881P 1996-05-17
GB9613183 1996-06-24
GBGB9613183.4A GB9613183D0 (en) 1996-06-24 1996-06-24 Effervescent alendronate formulation
PCT/US1997/008055 WO1997044017A1 (en) 1996-05-17 1997-05-13 Effervescent bisphosphonate formulation

Publications (2)

Publication Number Publication Date
HK1019555A1 true HK1019555A1 (en) 2000-02-18
HK1019555B HK1019555B (en) 2004-04-30

Family

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Also Published As

Publication number Publication date
EP0939624A1 (en) 1999-09-08
CA2254060A1 (en) 1997-11-27
JP2000511178A (ja) 2000-08-29
WO1997044017A1 (en) 1997-11-27
AU3005397A (en) 1997-12-09
EP0939624B1 (en) 2003-12-17
DE69726879T2 (de) 2004-10-14
CA2254060C (en) 2007-05-01
JP2009167200A (ja) 2009-07-30
DE69726879D1 (de) 2004-01-29
ATE256456T1 (de) 2004-01-15
AU712710B2 (en) 1999-11-11
ES2210529T3 (es) 2004-07-01

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Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20170512