ATE256456T1 - Biphosphonat-formulierung mit brausewirkung - Google Patents
Biphosphonat-formulierung mit brausewirkungInfo
- Publication number
- ATE256456T1 ATE256456T1 AT97924695T AT97924695T ATE256456T1 AT E256456 T1 ATE256456 T1 AT E256456T1 AT 97924695 T AT97924695 T AT 97924695T AT 97924695 T AT97924695 T AT 97924695T AT E256456 T1 ATE256456 T1 AT E256456T1
- Authority
- AT
- Austria
- Prior art keywords
- formulation
- effortable
- biphosphonate
- effect
- source
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- OGSPWJRAVKPPFI-UHFFFAOYSA-N Alendronic Acid Chemical compound NCCCC(O)(P(O)(O)=O)P(O)(O)=O OGSPWJRAVKPPFI-UHFFFAOYSA-N 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229940062527 alendronate Drugs 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 239000003086 colorant Substances 0.000 abstract 1
- 239000000796 flavoring agent Substances 0.000 abstract 1
- 235000013355 food flavoring agent Nutrition 0.000 abstract 1
- 235000003599 food sweetener Nutrition 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 239000003765 sweetening agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1788196P | 1996-05-17 | 1996-05-17 | |
| GBGB9613183.4A GB9613183D0 (en) | 1996-06-24 | 1996-06-24 | Effervescent alendronate formulation |
| PCT/US1997/008055 WO1997044017A1 (en) | 1996-05-17 | 1997-05-13 | Effervescent bisphosphonate formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE256456T1 true ATE256456T1 (de) | 2004-01-15 |
Family
ID=26309559
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97924695T ATE256456T1 (de) | 1996-05-17 | 1997-05-13 | Biphosphonat-formulierung mit brausewirkung |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0939624B1 (de) |
| JP (2) | JP2000511178A (de) |
| AT (1) | ATE256456T1 (de) |
| AU (1) | AU712710B2 (de) |
| CA (1) | CA2254060C (de) |
| DE (1) | DE69726879T2 (de) |
| ES (1) | ES2210529T3 (de) |
| HK (1) | HK1019555A1 (de) |
| WO (1) | WO1997044017A1 (de) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1175904E (pt) * | 1997-07-22 | 2007-04-30 | Merck & Co Inc | Alendronato para utilização no tratamento da osteoporose |
| IT1293764B1 (it) * | 1997-07-23 | 1999-03-10 | Chiesi Farma Spa | Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua |
| IL121623A (en) * | 1997-08-26 | 2000-06-29 | Unipharm Ltd | Process for the preparation of solid oral dosage forms comprising alendronic acid |
| US6974590B2 (en) | 1998-03-27 | 2005-12-13 | Cima Labs Inc. | Sublingual buccal effervescent |
| US20030091629A1 (en) | 1998-03-27 | 2003-05-15 | Cima Labs Inc. | Sublingual buccal effervescent |
| US7658938B2 (en) | 1999-02-22 | 2010-02-09 | Merrion Reasearch III Limited | Solid oral dosage form containing an enhancer |
| PE20011061A1 (es) | 2000-02-01 | 2001-11-20 | Procter & Gamble | Cristalizacion selectiva del acido 3-piridil-1-hidroxi-etiliden-1,1-bisfosfonico sodio como el hemipentahidrato o el monohidrato |
| EP1228761A3 (de) * | 2001-02-01 | 2003-01-15 | Riderway Corporation | Flüssige pharmazeutische Zusammensetzung zur Behandlung von Knochenerkrankungen |
| US7488496B2 (en) | 2002-03-06 | 2009-02-10 | Christer Rosen | Effervescent compositions comprising bisphosphonates and methods related thereto |
| EP2277503B1 (de) * | 2002-03-06 | 2014-02-12 | EffRx Pharmaceuticals SA | Brausetabletten, enthaltend Bisphosphonate |
| GR1004660B (el) * | 2003-06-25 | 2004-08-25 | ������������, �������� ��� ����������� �������� �������� ��� �.�. ��������-������������ �.�. | Βελτιωμενες φαρμακευτικες συνθεσεις του τριυδρικου αλενδρονικου νατριου και μεθοδοι παρασκευης τους |
| ATE498395T1 (de) | 2003-12-31 | 2011-03-15 | Cima Labs Inc | Allgemein lineare brauseform von fentanyl zur oralen anwendung und verfahren zur verabreichung |
| US7858121B2 (en) | 2003-12-31 | 2010-12-28 | Cima Labs, Inc. | Effervescent oral fentanyl dosage form and methods of administering fentanyl |
| NZ548215A (en) | 2003-12-31 | 2009-08-28 | Cima Labs Inc | Effervescent oral opiate dosage form |
| US7645460B2 (en) | 2004-05-24 | 2010-01-12 | The Procter & Gamble Company | Dosage forms of risedronate |
| ES2921141T3 (es) * | 2004-05-24 | 2022-08-18 | Theramex Hq Uk Ltd | Forma farmacéutica oral sólida entérica de un bisfosfonato que contiene un agente quelante |
| US7645459B2 (en) | 2004-05-24 | 2010-01-12 | The Procter & Gamble Company | Dosage forms of bisphosphonates |
| US20080286359A1 (en) | 2004-05-24 | 2008-11-20 | Richard John Dansereau | Low Dosage Forms Of Risedronate Or Its Salts |
| US20080287400A1 (en) | 2004-05-24 | 2008-11-20 | Richard John Dansereau | Low Dosage Forms Of Risedronate Or Its Salts |
| WO2006020009A1 (en) * | 2004-07-23 | 2006-02-23 | The Procter & Gamble Company | Solid oral dosage form of a bisphosphonate containing a chelating agent |
| WO2006100527A1 (en) * | 2005-03-24 | 2006-09-28 | Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. | Effervescent tablet containing sodium alendronate and related use and process |
| DE102006054260A1 (de) * | 2006-02-28 | 2007-09-27 | Lohmann Animal Health Gmbh & Co. Kg | Wasser stabilisierende Zusammensetzung, Verfahren zu deren Herstellung und deren Verwendung |
| RU2437662C2 (ru) | 2006-04-07 | 2011-12-27 | Меррион Рисерч Iii Лимитед | Твердая пероральная лекарственная форма, содержащая усилитель |
| EP2055297A1 (de) * | 2007-11-05 | 2009-05-06 | Merz Pharma GmbH & Co. KGaA | Behandlungsverfahren zur Rückfärbung von Haaren mittels Bisphosphonaten durch physiologische Repigmentierung bei aus Altersgründen oder vorzeitig ergrauten Patienten |
| CN102056615A (zh) | 2008-05-07 | 2011-05-11 | 默里昂研究Ⅲ有限公司 | 肽的组合物及其制备方法 |
| KR101118794B1 (ko) | 2009-11-10 | 2012-06-13 | 동아제약주식회사 | 비스포스포네이트를 함유하는 약학 조성물 |
| FR2954320B1 (fr) | 2009-12-17 | 2012-06-15 | Cll Pharma | Composition pharmaceutique orale suprabiodisponible contenant un acide biphosphonique ou un de ses sels |
| US20110182985A1 (en) * | 2010-01-28 | 2011-07-28 | Coughlan David C | Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof |
| WO2011120033A1 (en) | 2010-03-26 | 2011-09-29 | Merrion Research Iii Limited | Pharmaceutical compositions of selective factor xa inhibitors for oral administration |
| TR201100151A2 (tr) * | 2011-01-06 | 2012-07-23 | Bi̇lgi̇ç Mahmut | İbandronate formülasyonu. |
| BR112015022739A2 (pt) * | 2013-03-15 | 2017-07-18 | Mylan Inc | processo de fabricação para uma forma de dosagem efervescente |
| ES2975708T3 (es) | 2015-01-29 | 2024-07-12 | Novo Nordisk As | Comprimidos que comprenden agonista del GLP-1 y recubrimiento entérico |
| CN116173068B (zh) * | 2022-12-14 | 2025-02-07 | 嘉实（湖南）医药科技有限公司 | 一种复方磷酸盐颗粒的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1201087B (it) * | 1982-04-15 | 1989-01-27 | Gentili Ist Spa | Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche |
| IT1195993B (it) * | 1984-01-12 | 1988-11-03 | Gentili Ist Spa | Forme farmaceutiche a base di difosfonati |
| FR2633181B1 (fr) * | 1988-06-24 | 1992-01-10 | Glaxo Lab Sa | Composition pharmaceutique a base de ranitidine et son procede de preparation |
| DE59202126D1 (de) * | 1991-07-01 | 1995-06-14 | Gergely Gerhard | Verfahren zur Herstellung einer pharmazeutischen Zubereitung mit wenigstens zwei verschiedenen Wirkstoffen und Verwendung einer solchen Zubereitung. |
| US5270365A (en) * | 1991-12-17 | 1993-12-14 | Merck & Co., Inc. | Prevention and treatment of periodontal disease with alendronate |
| JPH08505142A (ja) * | 1992-12-23 | 1996-06-04 | メルク エンド カンパニー インコーポレーテッド | 骨損失を治療及び予防するためのビスホスホネート／エストロゲン療法 |
| US5656288A (en) * | 1995-06-08 | 1997-08-12 | Sanofi Winthrop, Inc. | Stable pharmaceutical compositions containing tiludronate hydrates and process for producing the pharmaceutical compositions |
-
1997
- 1997-05-13 AU AU30053/97A patent/AU712710B2/en not_active Expired
- 1997-05-13 DE DE69726879T patent/DE69726879T2/de not_active Expired - Lifetime
- 1997-05-13 JP JP09542490A patent/JP2000511178A/ja not_active Ceased
- 1997-05-13 EP EP97924695A patent/EP0939624B1/de not_active Expired - Lifetime
- 1997-05-13 AT AT97924695T patent/ATE256456T1/de not_active IP Right Cessation
- 1997-05-13 ES ES97924695T patent/ES2210529T3/es not_active Expired - Lifetime
- 1997-05-13 WO PCT/US1997/008055 patent/WO1997044017A1/en active IP Right Grant
- 1997-05-13 CA CA002254060A patent/CA2254060C/en not_active Expired - Lifetime
-
1999
- 1999-10-22 HK HK99104703A patent/HK1019555A1/xx not_active IP Right Cessation
-
2009
- 2009-03-17 JP JP2009063857A patent/JP2009167200A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0939624B1 (de) | 2003-12-17 |
| WO1997044017A1 (en) | 1997-11-27 |
| CA2254060A1 (en) | 1997-11-27 |
| CA2254060C (en) | 2007-05-01 |
| HK1019555A1 (en) | 2000-02-18 |
| AU712710B2 (en) | 1999-11-11 |
| DE69726879T2 (de) | 2004-10-14 |
| AU3005397A (en) | 1997-12-09 |
| EP0939624A1 (de) | 1999-09-08 |
| JP2000511178A (ja) | 2000-08-29 |
| JP2009167200A (ja) | 2009-07-30 |
| ES2210529T3 (es) | 2004-07-01 |
| DE69726879D1 (de) | 2004-01-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |