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GT200800256A - Derivados de pirazolo [3,4-d]-pirimidina útiles para tratar trastornos respiratorios - Google Patents

Derivados de pirazolo [3,4-d]-pirimidina útiles para tratar trastornos respiratorios

Info

Publication number
GT200800256A
GT200800256A GT200800256A GT200800256A GT200800256A GT 200800256 A GT200800256 A GT 200800256A GT 200800256 A GT200800256 A GT 200800256A GT 200800256 A GT200800256 A GT 200800256A GT 200800256 A GT200800256 A GT 200800256A
Authority
GT
Guatemala
Prior art keywords
pirazolo
pirimidine
derivatives
useful
respiratory disorders
Prior art date
Application number
GT200800256A
Other languages
English (en)
Inventor
Bruce Ian
Hayler Judy Fox
Bloomfield Graham Charles
Edwards Lee
Cox Brian
Howsham Catherine
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36687588&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GT200800256(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of GT200800256A publication Critical patent/GT200800256A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA PRESENTE INVENCIÓN SE REFIERE A UN COMPUESTO DE LA FÓRMULA I O UNA SAL FARMACÉUTICA ACEPATABLE O UN SOLVATO DEL MISMO DONDE R1-R3 SE DEFINEN EN LA DESCRIPCIÓN, A COMPOSICIONES Y AL USO DE LOS COMPUESTOS EN EL TRATAMIENTO DE ENFERMEDADES QUE SE ALIVIAN MEDIANTE LA INHIBICIÓN DE LA 3-CINASA DE FOSFATIDIL-INOSITOL. T2008
GT200800256A 2006-05-23 2008-11-21 Derivados de pirazolo [3,4-d]-pirimidina útiles para tratar trastornos respiratorios GT200800256A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0610242.0A GB0610242D0 (en) 2006-05-23 2006-05-23 Organic compounds

Publications (1)

Publication Number Publication Date
GT200800256A true GT200800256A (es) 2009-05-28

Family

ID=36687588

Family Applications (1)

Application Number Title Priority Date Filing Date
GT200800256A GT200800256A (es) 2006-05-23 2008-11-21 Derivados de pirazolo [3,4-d]-pirimidina útiles para tratar trastornos respiratorios

Country Status (24)

Country Link
US (5) US20090131457A1 (es)
EP (1) EP2026811A1 (es)
JP (1) JP2009537580A (es)
KR (1) KR101106853B1 (es)
CN (1) CN101443013A (es)
AR (2) AR061057A1 (es)
AU (1) AU2007253615B2 (es)
BR (1) BRPI0712022A2 (es)
CA (1) CA2650661A1 (es)
CL (1) CL2007001455A1 (es)
CR (1) CR10419A (es)
EC (1) ECSP088902A (es)
GB (1) GB0610242D0 (es)
GT (1) GT200800256A (es)
IL (1) IL195017A0 (es)
MA (1) MA30433B1 (es)
MX (1) MX2008014835A (es)
NO (1) NO20084997L (es)
PE (1) PE20080315A1 (es)
RU (1) RU2008150619A (es)
TN (1) TNSN08478A1 (es)
TW (1) TW200806665A (es)
WO (1) WO2007134828A1 (es)
ZA (1) ZA200809097B (es)

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WO2013077921A2 (en) 2011-09-02 2013-05-30 The Regents Of The University Of California Substituted pyrazolo[3,4-d]pyrimidines and uses thereof
JP5796130B2 (ja) 2011-09-14 2015-10-21 プロクシマゲン リミテッド 新規な酵素阻害剤化合物
GB201115853D0 (en) 2011-09-14 2011-10-26 Proximagen Ltd New enzyme inhibitor compounds
BR112014007788A2 (pt) 2011-10-03 2017-04-18 Univ North Carolina Chapel Hill compostos de pirrolopirimidina para tratamento do câncer
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Also Published As

Publication number Publication date
US8901134B2 (en) 2014-12-02
US20140235632A1 (en) 2014-08-21
US20090131457A1 (en) 2009-05-21
US20140051698A1 (en) 2014-02-20
AR061057A1 (es) 2008-07-30
KR101106853B1 (ko) 2012-01-19
GB0610242D0 (en) 2006-07-05
JP2009537580A (ja) 2009-10-29
ECSP088902A (es) 2008-12-30
AU2007253615B2 (en) 2011-06-23
TNSN08478A1 (en) 2010-04-14
CL2007001455A1 (es) 2008-05-16
ZA200809097B (en) 2009-11-25
CN101443013A (zh) 2009-05-27
AR110051A2 (es) 2019-02-20
US20180125849A1 (en) 2018-05-10
MA30433B1 (fr) 2009-05-04
US20160303132A1 (en) 2016-10-20
RU2008150619A (ru) 2010-06-27
MX2008014835A (es) 2008-12-01
TW200806665A (en) 2008-02-01
NO20084997L (no) 2008-12-22
BRPI0712022A2 (pt) 2011-12-27
WO2007134828A1 (en) 2007-11-29
PE20080315A1 (es) 2008-06-11
EP2026811A1 (en) 2009-02-25
CR10419A (es) 2011-07-19
CA2650661A1 (en) 2007-11-29
IL195017A0 (en) 2009-08-03
KR20090008392A (ko) 2009-01-21
AU2007253615A1 (en) 2007-11-29

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