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GT199800183A - Imidazotriazinonas sustituidas por 2-fenilo. - Google Patents

Imidazotriazinonas sustituidas por 2-fenilo.

Info

Publication number
GT199800183A
GT199800183A GT199800183A GT199800183A GT199800183A GT 199800183 A GT199800183 A GT 199800183A GT 199800183 A GT199800183 A GT 199800183A GT 199800183 A GT199800183 A GT 199800183A GT 199800183 A GT199800183 A GT 199800183A
Authority
GT
Guatemala
Prior art keywords
imidazotriazinonas
fenilo
replaced
gmpc
imidazotriazinones
Prior art date
Application number
GT199800183A
Other languages
English (en)
Inventor
Ulrich Dr Niewohner
Mazen Dr Es-Sayed
Helmut Dr Haning
Thomas Dr Schenke
Karl-Heinz Dr Schlemmer
Jorg Dr Keldenich
Erwin Dr Bischoff
Elizabeth Dr Perzborn
Klaus Dr Dembowsky
Peter Dr Serno
Marc Dr Nowakowski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT199800183A publication Critical patent/GT199800183A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LAS IMIDAZOTRIAZINONAS SUSTITUIDAS POR 2FENILO CON RESTOS ALQUILO CORTOS, NO RAMIFICADOS, EN POSICION 9, SE PREPARAN A PARTIR DE LAS CORRESPONDIENTES 2FENILIMIDAZOTRIAZINONAS MEDIANTE CLOROSULFONACION Y TRANSFORMACION POSTERIOR CON LAS AMINAS. LOS COMPUESTOS INHIBEN LAS FOSFODIESTERASAS QUE METABOLIZAN EL GMPC Y SON ADECUADAS COMO SUSTANCIA ACTIVA EN MEDICAMENTOS PARA EL TRATAMIENTO DE ENFERMEDADES CARDIOVASCULARES Y CEREBROVASCULARES.
GT199800183A 1997-11-12 1998-11-11 Imidazotriazinonas sustituidas por 2-fenilo. GT199800183A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19750085A DE19750085A1 (de) 1997-11-12 1997-11-12 2-Phenyl-substituierte Imidazotriazinone

Publications (1)

Publication Number Publication Date
GT199800183A true GT199800183A (es) 2000-05-04

Family

ID=7848473

Family Applications (1)

Application Number Title Priority Date Filing Date
GT199800183A GT199800183A (es) 1997-11-12 1998-11-11 Imidazotriazinonas sustituidas por 2-fenilo.

Country Status (6)

Country Link
DE (1) DE19750085A1 (es)
EC (1) ECSP024267A (es)
GT (1) GT199800183A (es)
RU (1) RU2260593C2 (es)
SV (1) SV1998000135A (es)
ZA (1) ZA9810297B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0113343D0 (en) * 2001-06-01 2001-07-25 Bayer Ag Novel Heterocycles 2
MX2013003093A (es) * 2010-09-20 2013-10-28 Envivo Pharmaceuticals Inc Compuestos de imidazotriazinona.
CN102134242B (zh) * 2011-01-21 2013-08-28 浙江大德药业集团有限公司 一种用于治疗阳痿的快速长效的化合物

Also Published As

Publication number Publication date
DE19750085A1 (de) 1999-05-20
ECSP024267A (es) 2002-06-26
RU2260593C2 (ru) 2005-09-20
SV1998000135A (es) 1999-03-09
ZA9810297B (en) 1999-05-20

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