GR920100520A - Compounds. - Google Patents
Compounds.Info
- Publication number
- GR920100520A GR920100520A GR920100520A GR920100520A GR920100520A GR 920100520 A GR920100520 A GR 920100520A GR 920100520 A GR920100520 A GR 920100520A GR 920100520 A GR920100520 A GR 920100520A GR 920100520 A GR920100520 A GR 920100520A
- Authority
- GR
- Greece
- Prior art keywords
- useful
- intervention
- inhibition
- compounds
- disease conditions
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000005764 inhibitory process Effects 0.000 abstract 2
- 102000011017 Type 4 Cyclic Nucleotide Phosphodiesterases Human genes 0.000 abstract 1
- 108010037584 Type 4 Cyclic Nucleotide Phosphodiesterases Proteins 0.000 abstract 1
- 230000003197 catalytic effect Effects 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 230000017074 necrotic cell death Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000006433 tumor necrosis factor production Effects 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
New cyclohexano-hylidene derivatives are described which interrupt production of the carcinomal necrosis factor and are useful for the treatment of disease conditions which promote or aggravate TNF production. The compounds of this invention are also useful in intervention with or inhibition of the enzymatic or catalytic action of phosphodiesterase IV and, therefore, they are useful for therapeutic treatment of disease conditions requiring their intervention or inhibition.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR92100520 | 1992-11-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
GR920100520A true GR920100520A (en) | 1994-07-29 |
Family
ID=10941241
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR920100520A GR920100520A (en) | 1992-11-26 | 1992-11-26 | Compounds. |
Country Status (1)
Country | Link |
---|---|
GR (1) | GR920100520A (en) |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2723937A1 (en) * | 1976-06-03 | 1977-12-15 | Upjohn Co | 4-AMINO-4-ARYLCYCLOHEXANONE COMPOUNDS, METHODS FOR THEIR MANUFACTURING, INTERMEDIATES USED IN THEIR MANUFACTURING, AND MEDICINAL PRODUCTS |
US4795757A (en) * | 1984-09-04 | 1989-01-03 | Rorer Pharmaceutical Corporation | Bisarylamines |
WO1991015451A1 (en) * | 1990-04-05 | 1991-10-17 | Smithkline Beecham Pharma Gmbh | Novel derivatives of phenyl-cycloalkanes and -cycloalkenes |
-
1992
- 1992-11-26 GR GR920100520A patent/GR920100520A/en unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2723937A1 (en) * | 1976-06-03 | 1977-12-15 | Upjohn Co | 4-AMINO-4-ARYLCYCLOHEXANONE COMPOUNDS, METHODS FOR THEIR MANUFACTURING, INTERMEDIATES USED IN THEIR MANUFACTURING, AND MEDICINAL PRODUCTS |
US4795757A (en) * | 1984-09-04 | 1989-01-03 | Rorer Pharmaceutical Corporation | Bisarylamines |
WO1991015451A1 (en) * | 1990-04-05 | 1991-10-17 | Smithkline Beecham Pharma Gmbh | Novel derivatives of phenyl-cycloalkanes and -cycloalkenes |
Non-Patent Citations (1)
Title |
---|
CHEMICAL ABSTRACTS, vol. 73, no. 21, 23 November 1970, Columbus, Ohio, US; abstract no. 109530f, '4-CYANO-4-PHENYLAMINOCYCLOHEXANES, BLOOD PRESSURE DEPRESSANTS' page 347 ; * |
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