GR3004990T3 - - Google Patents
Info
- Publication number
- GR3004990T3 GR3004990T3 GR920401326T GR920401326T GR3004990T3 GR 3004990 T3 GR3004990 T3 GR 3004990T3 GR 920401326 T GR920401326 T GR 920401326T GR 920401326 T GR920401326 T GR 920401326T GR 3004990 T3 GR3004990 T3 GR 3004990T3
- Authority
- GR
- Greece
- Prior art keywords
- carnitine
- aminoacid
- protected
- propyl
- mercaptomethyl
- Prior art date
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 2
- 235000001014 amino acid Nutrition 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 125000003974 3-carbamimidamidopropyl group Chemical group C(N)(=N)NCCC* 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 229960004203 carnitine Drugs 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- -1 mercaptomethyl Chemical group 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
- C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8648217A IT1208753B (it) | 1986-07-02 | 1986-07-02 | L-amminoacil derivati della l-carnitina, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' epatoprotettrice che li contengono |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3004990T3 true GR3004990T3 (el) | 1993-04-28 |
Family
ID=11265298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR920401326T GR3004990T3 (el) | 1986-07-02 | 1992-06-19 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US4812478A (el) |
| EP (1) | EP0252030B1 (el) |
| AT (1) | ATE77366T1 (el) |
| DE (1) | DE3779819T2 (el) |
| ES (1) | ES2039476T3 (el) |
| GR (1) | GR3004990T3 (el) |
| IT (1) | IT1208753B (el) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1224842B (it) * | 1988-12-27 | 1990-10-24 | Sigma Tau Ind Farmaceuti | Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso |
| IT1240790B (it) * | 1990-03-06 | 1993-12-17 | Sigma Tau Ind Farmaceuti | Alfa-ammino-omega-alchiltioacilcarnitine e composizioni farmaceutiche contenenti tali composti ad attivita' sul sistema cardiovascolare. |
| IT1248321B (it) * | 1991-05-15 | 1995-01-05 | Sigma Tau Ind Farmaceuti | Uso di esteri di acil l-carnitine con l'acido gamma-idrossibutirrico per produrre composizioni farmaceutiche per il trattamento di epatopatie |
| US5569457A (en) * | 1994-11-18 | 1996-10-29 | Shug; Austin L. | Method of stimulating antibody formation |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1156840B (it) * | 1978-06-27 | 1987-02-04 | Sigma Tau Ind Farmaceuti | Acil derivati della carnitina |
| IT1145371B (it) * | 1980-05-30 | 1986-11-05 | Sigma Tau Ind Farmaceuti | Alcossi-acil carnitine procedimento per la loro preparazione e composizioni farmaceutiche che le contengono |
| DE3463261D1 (en) * | 1983-12-28 | 1987-05-27 | Sigma Tau Ind Farmaceuti | Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same |
| IT1181682B (it) * | 1985-06-11 | 1987-09-30 | Sigma Tau Ind Farmaceuti | Impiego di alcanoil l-carnitine per il trattamento terapeutico del parkinsonismo idiopatico o indotto |
-
1986
- 1986-07-02 IT IT8648217A patent/IT1208753B/it active
-
1987
- 1987-06-29 US US07/067,694 patent/US4812478A/en not_active Expired - Fee Related
- 1987-07-01 DE DE8787830245T patent/DE3779819T2/de not_active Expired - Lifetime
- 1987-07-01 ES ES198787830245T patent/ES2039476T3/es not_active Expired - Lifetime
- 1987-07-01 EP EP87830245A patent/EP0252030B1/en not_active Expired - Lifetime
- 1987-07-01 AT AT87830245T patent/ATE77366T1/de not_active IP Right Cessation
-
1988
- 1988-11-08 US US07/268,751 patent/US4868211A/en not_active Expired - Fee Related
-
1992
- 1992-06-19 GR GR920401326T patent/GR3004990T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IT1208753B (it) | 1989-07-10 |
| US4812478A (en) | 1989-03-14 |
| IT8648217A0 (it) | 1986-07-02 |
| DE3779819D1 (de) | 1992-07-23 |
| ATE77366T1 (de) | 1992-07-15 |
| DE3779819T2 (de) | 1992-12-24 |
| US4868211A (en) | 1989-09-19 |
| EP0252030A3 (en) | 1988-11-02 |
| ES2039476T3 (es) | 1993-10-01 |
| EP0252030B1 (en) | 1992-06-17 |
| EP0252030A2 (en) | 1988-01-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| LU88321I2 (fr) | Quinapril (Accupril) | |
| KR840004070A (ko) | 2-아자스피로[4(3+m)]-3-카복실산 유도체의 제조방법 | |
| GR3004990T3 (el) | ||
| ES535354A0 (es) | Procedimiento para preparar derivados cefemicos | |
| ES2057116T3 (es) | Derivados de acido n-(5,6,7,8-tetrahidropirido-(2,3-d)pirimidin-6-ilalcanoil) glutamico. | |
| RU1804462C (en) | Method of cefem compounds or theirs salts synthesis | |
| BR8208033A (pt) | Processo quimico | |
| FI874586A0 (fi) | Syntes av peptid-aminoalkylaminer och peptidhydrazider medelst fastfasfoerfarande. | |
| JPS55151555A (en) | Proline derivatives and their production | |
| ES2040223T3 (es) | Derivados de la tiadiazolilacetamida, procedimiento para su fabricacion y su utilizacion. | |
| JPS57192348A (en) | Decaprenyl-substituted amino acid derivative | |
| PT84870A (pt) | Processo para a preparacao de derivados da cefalosporina | |
| JPS53108923A (en) | Epoxysuccinylamino acid derivative | |
| JPS557255A (en) | Thiazolidine derivative | |
| JPS6485955A (en) | Dialkyl ester of phthalic acid monoamide derivative and production thereof | |
| ES8603705A1 (es) | Procedimiento para la obtencion de la n-(2-(((5-(dimetilami-no)metil-2-furanil)metil)tio)etil)-n'-metil-2-nitro-1,1- etilendiamina |