GR3000418T3 - Preparation of fibrates - Google Patents

Preparation of fibrates

Info

Publication number: GR3000418T3
Authority: GR; Greece
Prior art keywords: fibrates; preparation; image; halogen atom; chlorobenzamido
Prior art date: 1986-04-30

Application number

GR90400186T

Other languages

English (en)

Inventor

Jean-Pierre Bourgogne

Roland Sornay

Original Assignee

Fournier Innovation Synergie

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-04-30

Filing date

1990-03-30

Publication date

1991-06-28

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9334781&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR3000418(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-03-30 Application filed by Fournier Innovation Synergie filed Critical Fournier Innovation Synergie

1991-06-28 Publication of GR3000418T3 publication Critical patent/GR3000418T3/el

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/708—Ethers
- C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Sampling And Sample Adjustment (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Drilling Tools (AREA)
Polishing Bodies And Polishing Tools (AREA)

GR90400186T 1986-04-30 1990-03-30 Preparation of fibrates GR3000418T3 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8606258A FR2598146B1 (fr)	1986-04-30	1986-04-30	Nouveau procede de preparation de fibrates.

Publications (1)

Publication Number	Publication Date
GR3000418T3 true GR3000418T3 (en)	1991-06-28

Family

ID=9334781

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR90400186T GR3000418T3 (en)	1986-04-30	1990-03-30	Preparation of fibrates

Country Status (9)

Country	Link
US (1)	US4739101A (el)
EP (1)	EP0245156B1 (el)
JP (1)	JPS62263146A (el)
AT (1)	ATE49195T1 (el)
CA (1)	CA1282424C (el)
DE (1)	DE3761307D1 (el)
ES (1)	ES2005059B3 (el)
FR (1)	FR2598146B1 (el)
GR (1)	GR3000418T3 (el)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0725725B2 (ja) *	1987-07-23	1995-03-22	保土谷化学工業株式会社	ベンズアミド誘導体
WO1989006643A1 (en) *	1988-01-22	1989-07-27	Kharkovsky Nauchno-Issledovatelsky Institut Endokr	UNDECYLIC ETHER n-CHLOROPHENOXYISOBUTYRIC ACID AND A PHARMACEUTICAL PREPARATION FOR TREATING HYPERLIPEMIA BASED ON IT
US5008439A (en) *	1988-03-21	1991-04-16	Hoechst Celanese Corporation	Synthesis of 2-(4-hydroxyphenoxy) alkanoic acid esters
IL102707A (en) *	1992-08-02	1996-11-14	Cherkez Stephen	Processes for the preparation of tyramine derivatives
EP0625504B1 (de)	1993-05-12	1997-08-27	HEUMANN PHARMA GmbH	Stabile und kristalline Form von Bezafibrat
US5412112A (en) *	1994-06-14	1995-05-02	Industrial Technology Research Institute	Derivatives and preparation of 2,2-dimethyl-5-substituted phenoxy-pentanoic acids
US6814977B1 (en)	1998-12-18	2004-11-09	Abbott Laboratories	Formulations comprising lipid-regulating agents
US7014864B1 (en)	1998-12-18	2006-03-21	Abbott Laboratories	Formulations comprising lipid-regulating agents
US6838091B2 (en)	1998-12-18	2005-01-04	Abbott Laboratories	Formulations comprising lipid-regulating agents
US6368622B2 (en)	1999-01-29	2002-04-09	Abbott Laboratories	Process for preparing solid formulations of lipid regulating agents with enhanced dissolution and absorption
US6383517B1 (en)	1999-01-29	2002-05-07	Abbott Laboratories	Process for preparing solid formulations of lipid-regulating agents with enhanced dissolution and absorption
US6180138B1 (en)	1999-01-29	2001-01-30	Abbott Laboratories	Process for preparing solid formulations of lipid-regulating agents with enhanced dissolution and absorption
US6719999B2 (en)	1999-03-31	2004-04-13	Abbott Laboratories	Formulations comprising lipid-regulating agents
US6372251B2 (en)	1999-06-11	2002-04-16	Abbott Laboratories	Formulations comprising lipid-regulating agents
US6982251B2 (en) *	2000-12-20	2006-01-03	Schering Corporation	Substituted 2-azetidinones useful as hypocholesterolemic agents
SI1413331T1 (sl) *	2001-01-26	2008-02-29	Schering Corp	Kombinacije fenofibrata peroksisomskega proliferator aktivirajocega receptorja (PPAR) z ezetimib zaviralcem absorpcije sterola za vaskularne indikacije
BR0206639A (pt) *	2001-01-26	2004-02-25	Schering Corp	Combinações de inibidor(es) da absorção do esterol com modificador(es) do sangue para o tratamento de condições vasculares
US20060287254A1 (en) *	2001-01-26	2006-12-21	Schering Corporation	Use of substituted azetidinone compounds for the treatment of sitosterolemia
KR20040025889A (ko) *	2001-01-26	2004-03-26	쉐링 코포레이션	혈관성 질환을 치료하기 위한 스테롤 흡수 억제제와심혈관성 제제의 조합물
MXPA03006631A (es) *	2001-01-26	2004-03-18	Schering Corp	Combinaciones de secuestrante(s) de los acidos biliares y de inhibidor(es) de la absorcion de los esteroles, y tratamiento para indicaciones vasculares.
AU2002240050A1 (en) *	2001-01-26	2002-08-06	Schering Corporation	Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications
US7071181B2 (en) *	2001-01-26	2006-07-04	Schering Corporation	Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
PL205343B1 (pl) *	2001-01-26	2010-04-30	Schering Corp	Zastosowanie inhibitora wchłaniania sterolu
ITMI20010203A1 (it) *	2001-02-02	2002-08-02	Solchem Italiana Spa	Processo per la preparazione di fibrati
ITMI20010936A1 (it) *	2001-05-08	2002-11-08	Laboratorio Chimico Int Spa	Processo per la produzione di acidi 2-4-(2,2-dialociclopropil)fenossi\|-alcanoici e loro esteri
DE60216275T2 (de) *	2001-05-25	2007-06-21	Schering Corp.	Verwendung von mit azetidinon substituierten derivaten bei der behandlung der alzheimer-krankheit
US20030119808A1 (en) *	2001-09-21	2003-06-26	Schering Corporation	Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
CN1556700A (zh) *	2001-09-21	2004-12-22	��鹫˾	使用甾醇吸收抑制剂治疗或预防脉管炎的方法
US7053080B2 (en) *	2001-09-21	2006-05-30	Schering Corporation	Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US7056906B2 (en) *	2001-09-21	2006-06-06	Schering Corporation	Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
MXPA04002573A (es) *	2001-09-21	2004-06-18	Schering Corp	Tratamiento de xantoma con derivados de azetidinona como inhibidores de la absorcion de esterol.
MXPA05004811A (es) *	2002-11-06	2005-07-22	Schering Corp	Inhibidores de absorcion de colesterol para el tratamiento de trastornos autoinmunes.
WO2004081004A1 (en)	2003-03-07	2004-09-23	Schering Corporation	Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
US7459442B2 (en) *	2003-03-07	2008-12-02	Schering Corporation	Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
DE602004018617D1 (de) *	2003-03-07	2009-02-05	Schering Corp	Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
US7235543B2 (en)	2003-03-07	2007-06-26	Schering Corporation	Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP2007510659A (ja) *	2003-11-05	2007-04-26	シェーリング　コーポレイション	脂質調節剤および置換アゼチジノンの組み合わせならびに血管状態の処置
US8062664B2 (en) *	2003-11-12	2011-11-22	Abbott Laboratories	Process for preparing formulations of lipid-regulating drugs
FR2892721B1 (fr) *	2005-10-28	2009-07-24	Synkem Sa	Nouveau procede de preparation de sels d'acides et d'ammonium quaternaires
EP1837327A1 (en) *	2006-03-23	2007-09-26	SOLMAG S.p.A.	Method for preparing pure fenofibrate
EP2173701A1 (fr) *	2007-07-05	2010-04-14	Finorga	Procede de preparation du fenofibrate
CN103373921B (zh)	2012-04-26	2016-08-10	浙江海正药业股份有限公司	4-((取代苯基)二氟甲基)苯氧基羧酸衍生物及其制备方法和医药用途
WO2018018618A1 (zh) *	2016-07-29	2018-02-01	浙江工业大学	一种非诺贝特的晶型及其制备方法
CN107698422A (zh) *	2017-08-21	2018-02-16	赵剑锋	一种2‑[4‑(4‑ 氯苯甲酰) 苯氧基]‑2‑ 甲基丙酸的合成工艺

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2060573A1 (de) *	1969-12-18	1971-06-24	Ciba Geigy Ag	Neue Carbonsaeuren und Verfahren zu ihrer Herstellung
US3795691A (en) *	1971-06-23	1974-03-05	American Home Prod	Cholesterol-lowering agents
US3759950A (en) *	1971-09-20	1973-09-18	American Home Prod	2-phenoxyalkanoic acid esters
CH626318A5 (el) *	1977-03-08	1981-11-13	Ciba Geigy Ag
IT1141655B (it) *	1980-02-12	1986-10-08	Schiapparelli Spa	Nuovi derivati dell'acido propanoico ad attivita' ipolipidemica e ipocolesterolemica
DE3150233A1 (de) *	1981-12-18	1983-06-30	Basf Ag, 6700 Ludwigshafen	Verfahren zur herstellung von 2-(hydroxiphenoxi)-carbonsaeureestern
US4661505A (en) *	1982-11-03	1987-04-28	Eli Lilly And Company	Leukotriene antagonists
IL71668A (en) *	1983-05-13	1988-07-31	Dow Chemical Co	Method of preparing esters of aryloxyphenoxy propanoic acid

1986
- 1986-04-30 FR FR8606258A patent/FR2598146B1/fr not_active Expired
1987
- 1987-04-27 CA CA000535685A patent/CA1282424C/en not_active Expired - Lifetime
- 1987-04-27 US US07/043,184 patent/US4739101A/en not_active Expired - Lifetime
- 1987-04-27 AT AT87400967T patent/ATE49195T1/de not_active IP Right Cessation
- 1987-04-27 EP EP87400967A patent/EP0245156B1/fr not_active Expired - Lifetime
- 1987-04-27 DE DE8787400967T patent/DE3761307D1/de not_active Expired - Lifetime
- 1987-04-27 ES ES87400967T patent/ES2005059B3/es not_active Expired - Lifetime
- 1987-04-28 JP JP62106179A patent/JPS62263146A/ja active Granted
1990
- 1990-03-30 GR GR90400186T patent/GR3000418T3/el unknown

Also Published As

Publication number	Publication date
EP0245156B1 (fr)	1990-01-03
US4739101A (en)	1988-04-19
FR2598146B1 (fr)	1989-01-20
CA1282424C (en)	1991-04-02
EP0245156A1 (fr)	1987-11-11
DE3761307D1 (de)	1990-02-08
JPS62263146A (ja)	1987-11-16
ATE49195T1 (de)	1990-01-15
ES2005059B3 (es)	1990-03-16
FR2598146A1 (fr)	1987-11-06
JPH0529343B2 (el)	1993-04-30
ES2005059A4 (es)	1989-03-01

Publication	Publication Date	Title
GR3000418T3 (en)	1991-06-28	Preparation of fibrates
WO1988000042A1 (en)	1988-01-14	New 5-alkoxy-2,4-diamino-alkyl benzols, and hair tinting means using them
AU575306B2 (en)	1988-07-28	Proline derivatives
ES548357A0 (es)	1987-01-16	Procedimiento para preparar derivados de n-(adamantil-1)-pirrolidon-5-carboxamida-2.
AU4611589A (en)	1990-06-28	Enzyme-inhibiting amino acid derivatives, a process for the preparation thereof, agents containing these, and the use thereof.
ES545009A0 (es)	1986-07-16	Procedimiento de preparacion de nuevas fenil-naftiridinas.
HUT39147A (en)	1986-08-28	Process for preparing phenoxy-propanol-acethylene derivatives and pharmaceutical compositions containing such compounds
AU568064B2 (en)	1987-12-17	4-acylamino-1-aza-adamantanes
ES2066756T3 (es)	1995-03-16	Nuevos derivados de tironina.
ATE101391T1 (de)	1994-02-15	Verfahren zur herstellung von in stellung 3 durch eine halogenierte gesaettigte kette substituierten cyclopropancarbonsaeurederivaten.
ES2006700B3 (es)	1992-04-01	Nuevos derivados de tironina.
DE68910931D1 (de)	1994-01-05	Verfahren zur Herstellung von Propionsäurederivaten.
AU2172688A (en)	1989-03-02	Preparation of dien-1-ols, 9-hydroxydodec-10-enyl 1-tert-butyl ether and use thereof as an intermediate for synthesizing, 8,10-dodecadienol
BR9106128A (pt)	1993-03-02	Sulfetos de n-acil-aminoalquil-2-hidroxietila e um processo para sua preparacao
ES2043631T3 (es)	1994-01-01	Procedimiento de preparacion de hidroxialquilxantinas.
ES2070121T3 (es)	1995-06-01	Procedimiento para la preparacion de 4-alcoxialquil-beta-carbolinas.
DE3660546D1 (en)	1988-09-22	Phosphoroimidates
AT383811B (de)	1987-08-25	Verfahren zur herstellung von monoalkalisalzen von 7-amino-3-cephem-4-carbonsaeurederivaten
ES536140A0 (es)	1985-06-01	Procedimiento para la preparacion de quinolinonas-4
ES2013316A6 (es)	1990-05-01	Un proceso para preparar un derivado de guanidinotiazol
DK74594A (da)	1994-06-22	Fremgangsmåde til fremstilling af paroxetin eller et farmaceutisk acceptabelt salt deraf