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GB968980A - Measles virus vaccine - Google Patents

Measles virus vaccine

Info

Publication number
GB968980A
GB968980A GB12640/64A GB1264064A GB968980A GB 968980 A GB968980 A GB 968980A GB 12640/64 A GB12640/64 A GB 12640/64A GB 1264064 A GB1264064 A GB 1264064A GB 968980 A GB968980 A GB 968980A
Authority
GB
United Kingdom
Prior art keywords
measles virus
vaccine
culture
cultures
wet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB12640/64A
Inventor
Gwenneth Doreen Lawrence
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Priority to GB12640/64A priority Critical patent/GB968980A/en
Publication of GB968980A publication Critical patent/GB968980A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/155Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/165Mumps or measles virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18411Morbillivirus, e.g. Measles virus, canine distemper
    • C12N2760/18434Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Measles vaccine containing living attenuated measles virus which has been grown in chick embryo tissue culture is produced by infecting chick embryo tissue culture with attenuated measles virus, incubating the infected culture at 32 DEG C. and harvesting a wet vaccine by collecting the liquid from the culture. In the example, cultures of 7-11 day old chick embryos incubated at 37 DEG C. until a confluent cell sheet was formed were infected with measles virus after washing with balanced salt solution both before and after inoculation. The cultures were fed with medium SM199 and incubated at 32 DEG C. for 7-14 days. Cell debris was removed by centrifugation, the wet vaccine harvested and freeze dried after the addition of sorbitol.
GB12640/64A 1961-09-08 1961-09-08 Measles virus vaccine Expired GB968980A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB12640/64A GB968980A (en) 1961-09-08 1961-09-08 Measles virus vaccine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB12640/64A GB968980A (en) 1961-09-08 1961-09-08 Measles virus vaccine

Publications (1)

Publication Number Publication Date
GB968980A true GB968980A (en) 1964-09-09

Family

ID=10008426

Family Applications (1)

Application Number Title Priority Date Filing Date
GB12640/64A Expired GB968980A (en) 1961-09-08 1961-09-08 Measles virus vaccine

Country Status (1)

Country Link
GB (1) GB968980A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4211843A (en) * 1977-11-30 1980-07-08 L'institut Armand-Frappier Strain of measles virus and process of producing the same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4211843A (en) * 1977-11-30 1980-07-08 L'institut Armand-Frappier Strain of measles virus and process of producing the same

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