GB939682A - Substituted malonic acid dinitriles - Google Patents
Substituted malonic acid dinitrilesInfo
- Publication number
- GB939682A GB939682A GB3821861A GB3821861A GB939682A GB 939682 A GB939682 A GB 939682A GB 3821861 A GB3821861 A GB 3821861A GB 3821861 A GB3821861 A GB 3821861A GB 939682 A GB939682 A GB 939682A
- Authority
- GB
- United Kingdom
- Prior art keywords
- prepared
- formamidinium
- substituted
- acid
- oxapentamethylene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/195—Radicals derived from nitrogen analogues of carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
N-substituted aminomalonic acid dinitriles are prepared by reacting 1 mol. of an N,N,N1,N1- tetrasubstituted formamidinium salt with at least 2 mols. of anhydrous hydrocyanic acid. Preferred N,N,N1,N1-tetra-substituted formamidinium salts have the formula:- <FORM:0939682/IV(a)/1> in which R and R1 separately represents aliphatic, cycloaliphatic or aromatic radicals which may be substituted by alkyl or alkoxy groups, chlorine or bromine or in which a group R together with an adjacent group R1 represent a C4-5 alkylene bridge in which one methylene group can be replaced by O, N or S, and X represents an anion such as that derived from hydrochloric, hydrobromic, hydroiodic, chloric, iodic, perchloric or sulphuric acid. The process yields amine salts as by-products. p N,N,N1,N1- Bis- (pentamethylene)- formamidinium chloride is prepared by heating excess of tetramethyl formamidinium chloride with excess piperidine. N,N,N1,N1- Bis- (3- oxapentamethylene)-formamidinium chloride is prepared by reacting N-formyl morpholine with chloroformic acid-3-oxapentamethylene amide. Chloroformic acid- 3- oxapentamethylene amide is prepared by reacting N-methyl morpholine with phosgene in boiling benzene.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF32561A DE1128431B (en) | 1960-11-16 | 1960-11-16 | Process for the preparation of basic substituted malonic dinitriles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB939682A true GB939682A (en) | 1963-10-16 |
Family
ID=7094685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3821861A Expired GB939682A (en) | 1960-11-16 | 1961-10-25 | Substituted malonic acid dinitriles |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE610352A (en) |
| CH (1) | CH396934A (en) |
| DE (1) | DE1128431B (en) |
| GB (1) | GB939682A (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105985263B (en) * | 2015-02-03 | 2019-02-15 | 兰州大学 | A kind of synthetic method of N,N-disubstituted amino-malononitrile compounds |
-
1960
- 1960-11-16 DE DEF32561A patent/DE1128431B/en active Pending
-
1961
- 1961-10-21 CH CH1219361A patent/CH396934A/en unknown
- 1961-10-25 GB GB3821861A patent/GB939682A/en not_active Expired
- 1961-11-16 BE BE610352A patent/BE610352A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE610352A (en) | 1962-03-16 |
| CH396934A (en) | 1965-08-15 |
| DE1128431B (en) | 1962-04-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB939516A (en) | Sulphonyl ureas | |
| Speziale et al. | N-Substituted glycinate and alaninate esters | |
| US3261865A (en) | N-(chlorobenzoyl)ureas | |
| GB968254A (en) | New dihalogeno-amine-benzylamines | |
| GB939682A (en) | Substituted malonic acid dinitriles | |
| GB1238417A (en) | ||
| GB1093228A (en) | Substituted pyridyl ureas and processes for their preparation | |
| GB943776A (en) | Improvements in or relating to 2-phenylcyclopropylureas | |
| US3270004A (en) | Disubstituted piperazines useful as schistosomiasis agents | |
| ES399787A1 (en) | Process for the manufacture of N,N-disubstituted carbamic acid halides | |
| GB936370A (en) | Isocyanates of furan and tetrahydrofuran | |
| US2597248A (en) | Nu-substituted amino-ethanols | |
| GB1472863A (en) | Intermediates for cephalosporin synthesis | |
| GB1415730A (en) | Preparation of substituted ureas | |
| US2677697A (en) | Basic derivatives of substituted cinnamic acids and methods of preparing same | |
| GB980262A (en) | N-substituted carbamyl chlorides and their preparation | |
| GB990876A (en) | Improvements in and relating to organic diamino carbonates | |
| GB1494117A (en) | Process for the preparation of acid amides | |
| GB952142A (en) | Phenylpiperazinylalkyl carbamates | |
| GB1257199A (en) | ||
| KR810000357B1 (en) | Preparation of Substituted Benzamides | |
| GB1124646A (en) | Organic mono and polyisocyanates | |
| GB765544A (en) | Production of amides and ketones having basic substituents | |
| NO830002L (en) | NEW PYRIDYLPROPYL THIOCARBONATES AND PROCEDURES FOR PREPARING THEREOF. | |
| GB1098598A (en) | Substituted n-tertiary-aminoalkyl-benzamides and their preparation |