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GB933368A - Process for the manufacture of ú ú¾ú´quinoline derivatives - Google Patents

Process for the manufacture of ú ú¾ú´quinoline derivatives

Info

Publication number
GB933368A
GB933368A GB12886/62A GB1288662A GB933368A GB 933368 A GB933368 A GB 933368A GB 12886/62 A GB12886/62 A GB 12886/62A GB 1288662 A GB1288662 A GB 1288662A GB 933368 A GB933368 A GB 933368A
Authority
GB
United Kingdom
Prior art keywords
ú3⁄4ú
manufacture
quinoline derivatives
bromide
sulphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB12886/62A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of GB933368A publication Critical patent/GB933368A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

In a process for the preparation of isoquinoline derivatives of the formulae <FORM:0933368/IV(a)/1> and <FORM:0933368/IV(a)/2> wherein A- represents an ion, hal represents a halogen atom and n represents 1, 2 or 3, a compound of the formula <FORM:0933368/IV(a)/3> is condensed with a halosubstituted benzaldehyde and the resulting condensation product hydrogenated, if desired. 1,2-Dimethyl- 6,7-dimethoxy- 3,4-dihydro-isoquinolinium iodide, bromide and methyl sulphate are prepared by reacting the tertiary base with methyl iodide, bromide and sulphate, respectively.
GB12886/62A 1961-04-14 1962-04-04 Process for the manufacture of ú ú¾ú´quinoline derivatives Expired GB933368A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH449061A CH413838A (en) 1961-04-14 1961-04-14 Process for the preparation of tetrahydroisoquinolines

Publications (1)

Publication Number Publication Date
GB933368A true GB933368A (en) 1963-08-08

Family

ID=4277073

Family Applications (1)

Application Number Title Priority Date Filing Date
GB12886/62A Expired GB933368A (en) 1961-04-14 1962-04-04 Process for the manufacture of ú ú¾ú´quinoline derivatives

Country Status (5)

Country Link
BE (1) BE616022A (en)
CH (1) CH413838A (en)
ES (1) ES276452A1 (en)
GB (1) GB933368A (en)
OA (1) OA00929A (en)

Also Published As

Publication number Publication date
ES276452A1 (en) 1962-10-16
CH413838A (en) 1966-05-31
OA00929A (en) 1968-03-22
BE616022A (en) 1962-10-05

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