GB923125A - Steroid compounds - Google Patents
Steroid compoundsInfo
- Publication number
- GB923125A GB923125A GB2531759A GB2531759A GB923125A GB 923125 A GB923125 A GB 923125A GB 2531759 A GB2531759 A GB 2531759A GB 2531759 A GB2531759 A GB 2531759A GB 923125 A GB923125 A GB 923125A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- general formula
- represents hydrogen
- keto
- above general
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
The invention comprises 4,6-pregnadienes of the general formula <FORM:0923125/IV(a)/1> wherein R represents hydrogen or an acyl group, R1 represents a hydroxyl or keto group, and X represents hydrogen or a halogen atom, and the 16-methyl group is in the a - and b -position, and the preparation thereof by reacting the corresponding 4-pregnene compounds with chloranil in an organic solvent such as t-butanol, at an elevated temperature. The 11-hydroxy compounds of the above general formula may be oxidised to the corresponding 11-keto compounds, and 21-ester compounds of the above general formula may be hydrolysed to 21-hydroxy compounds. Ester groups present may be a 21-acetate, 21-propionate or 21-butyrate. The preferred halogen at the 9-position is fluorine. Specifications 877,085 and 906,443 are referred to.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75340758A | 1958-08-06 | 1958-08-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB923125A true GB923125A (en) | 1963-04-10 |
Family
ID=25030512
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2531759A Expired GB923125A (en) | 1958-08-06 | 1959-07-23 | Steroid compounds |
Country Status (2)
Country | Link |
---|---|
BE (1) | BE581421A (en) |
GB (1) | GB923125A (en) |
-
1959
- 1959-07-23 GB GB2531759A patent/GB923125A/en not_active Expired
- 1959-08-06 BE BE581421A patent/BE581421A/en unknown
Also Published As
Publication number | Publication date |
---|---|
BE581421A (en) | 1960-02-08 |
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