Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB11268/61A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US71129Aexternal-prioritypatent/US3047568A/en
Application filed by American Cyanamid CofiledCriticalAmerican Cyanamid Co
Publication of GB912962ApublicationCriticalpatent/GB912962A/en
C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07J—STEROIDS
C07J75/00—Processes for the preparation of steroids in general
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Chemical & Material Sciences
(AREA)
Organic Chemistry
(AREA)
Health & Medical Sciences
(AREA)
General Health & Medical Sciences
(AREA)
Steroid Compounds
(AREA)
Abstract
The invention comprises 16-cyano steroids of the androstane or the estratriene series and a process for preparing a 16-cyano steroid by reacting a 16 - hydroxymethylene - 17 - keto steroid (or a tautomer thereof) with O,N-bis-trifluoroacetyl-hydroxylamine. The starting 16-hydroxymethylene steroid is obtained by reacting a 17-keto steroid with a lower alkyl formate, e.g. ethyl formate, in the presence of an alkaline condensing agent.
GB11268/61A1960-08-151961-03-28Steroids and method of producing same
ExpiredGB912962A
(en)