Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3386560A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyesult Gyogyszer es Tapszergyar
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyesult Gyogyszer es Tapszergyar
Egyt Gyogyszervegyeszeti Gyar
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Publication date
Application filed by Egyesult Gyogyszer es Tapszergyar, Egyt Gyogyszervegyeszeti GyarfiledCriticalEgyesult Gyogyszer es Tapszergyar
Publication of GB908161ApublicationCriticalpatent/GB908161A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
The invention comprises N-acylnortropan-3a - and -3b -ols of the skeletal structure <FORM:0908161/IV (b)/1> and their 6,7-epoxy substituted derivatives, in which R is a hydroxyl group or an ester grouping, R1 is an alkyl or alkenyl group or a halogen substituted or unsubstituted aralkyl group, and R2 is an oxygen or sulphur atom, and the preparation thereof by reacting the corresponding N-unsubstituted nortropan-3-ols or their esters, in the presence of acid binding agents, with carbonic acid half ester acid halides of the general formula R1-R2-CO-X in which X is a halogen atom. The acid halide and acid binding agent are added substantially simultaneously to the nor-tropane derivative to avoid an excessively alkaline reaction medium.
GB3386560A1960-05-091960-10-03N-acyl tropan-3-ols and esters thereof
ExpiredGB908161A
(en)