GB890622A - Therapeutically active product - Google Patents
Therapeutically active productInfo
- Publication number
- GB890622A GB890622A GB41988/59A GB4198859A GB890622A GB 890622 A GB890622 A GB 890622A GB 41988/59 A GB41988/59 A GB 41988/59A GB 4198859 A GB4198859 A GB 4198859A GB 890622 A GB890622 A GB 890622A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cobalt
- copper
- halide
- manganese
- iodide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A therapeutically active complex is obtained by reacting dissolved heparin with a halide or sulphate of sodium, potassium or cobalt; a halide of manganese or copper; or a hydroxide or carbonate of cobalt, manganese or copper. Preferably the heparin is dissolved in water and the inorganic substance added and the pH adjusted to a value greater than 4, and the reaction carried out at a temperature of 70 DEG to 135 DEG C., if necessary under pressure. The resulting product in solution or in solid form may be used in the treatment of coronary thrombosis and atherosclerosis. Specified inorganic substances are sodium iodide, potassium iodide, manganous iodide, cobalt iodide, cobalt chloride, copper chloride, cobalt sulphate, and cobalt carbonate.ALSO:A complex obtained by reacting dissolved heparin with a halide or sulphate of sodium, potassium or cobalt; a halide of manganese or copper; or a hydroxide or carbonate of cobalt, manganese or copper (see Group IV (a)) is used in aqueous solution in the treatment of coronary thrombosis and atherosclerosis.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH6732958A CH387007A (en) | 1958-12-15 | 1958-12-15 | Process for preparing a complex with therapeutic action |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB890622A true GB890622A (en) | 1962-03-07 |
Family
ID=4527869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB41988/59A Expired GB890622A (en) | 1958-12-15 | 1959-12-10 | Therapeutically active product |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE585539A (en) |
| CH (1) | CH387007A (en) |
| ES (1) | ES254078A1 (en) |
| FR (1) | FR464M (en) |
| GB (1) | GB890622A (en) |
| OA (1) | OA01092A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988009347A1 (en) * | 1987-05-29 | 1988-12-01 | Kabivitrum Ab | Novel heparin derivatives |
| US7790906B2 (en) | 2005-06-01 | 2010-09-07 | Pulsion Medical Systems Ag | Method for the purification of betaines |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4039665A (en) * | 1975-05-20 | 1977-08-02 | William T. Foley Foundation, Inc. | Method for the eradication of venous blemishes |
-
1958
- 1958-12-15 CH CH6732958A patent/CH387007A/en unknown
-
1959
- 1959-12-10 ES ES0254078A patent/ES254078A1/en not_active Expired
- 1959-12-10 BE BE585539A patent/BE585539A/en unknown
- 1959-12-10 GB GB41988/59A patent/GB890622A/en not_active Expired
-
1960
- 1960-08-29 FR FR837080A patent/FR464M/fr active Active
-
1964
- 1964-12-30 OA OA51210A patent/OA01092A/en unknown
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988009347A1 (en) * | 1987-05-29 | 1988-12-01 | Kabivitrum Ab | Novel heparin derivatives |
| EP0302034A1 (en) * | 1987-05-29 | 1989-02-01 | Kabi Pharmacia AB | Novel heparin derivatives, a process for their preparation and their use in pharmaceuticals |
| US7790906B2 (en) | 2005-06-01 | 2010-09-07 | Pulsion Medical Systems Ag | Method for the purification of betaines |
Also Published As
| Publication number | Publication date |
|---|---|
| ES254078A1 (en) | 1960-02-16 |
| OA01092A (en) | 1968-08-07 |
| FR464M (en) | 1961-05-02 |
| CH387007A (en) | 1965-01-31 |
| BE585539A (en) | 1960-04-01 |
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