GB708384A - Drug solutions and process for the manufacture thereof - Google Patents
Drug solutions and process for the manufacture thereofInfo
- Publication number
- GB708384A GB708384A GB6705/52A GB670552A GB708384A GB 708384 A GB708384 A GB 708384A GB 6705/52 A GB6705/52 A GB 6705/52A GB 670552 A GB670552 A GB 670552A GB 708384 A GB708384 A GB 708384A
- Authority
- GB
- United Kingdom
- Prior art keywords
- carbon atoms
- fatty acids
- alcohols
- acid
- specified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
Abstract
Drug solutions for percutaneous applications are prepared by dissolving the drug in one or more esters of non-cyclic fatty acids having an unbranched chain containing 7 to 14 carbon atoms, said esters not containing free hydroxyl groups. Specified fatty acids are heptanoic, octanoic, non-anoic, decanoic, undecanoic, dodecanoic, tridecanoic and tetradecanoic acids; derivatives thereof containing alkyl side chains of not more than five carbon atoms, e.g. 2-ethyl-heptanoic acid, 6-butyl-octanoic acid and 8-ethyl-undecanoic acid; unsaturated acids, e.g. undecylenic acid; mixtures of fatty acids, e.g. from natural sources, e.g. coconut oil or synthetic, e.g. oxidation of paraffins. Specified alcohols are mono-hydric alcohols of up to 4 C atoms, e.g. ethanol and butanol; dihydric alcohols, e.g. propylene glycol and trihydric alcohols, e.g. glycerine. The triglycerides are preferred, especially the mixed esters and ester mix-having an unbranched chain of 7 to 11 carbon atoms be larger than the proportion of fatty acids containing 12 to 14 carbon atoms. Specified drugs are fat-soluble vitamins, e.g. vitamin A, hormones, e.g. testosterone propionate, keratolytic substances and antimycotics.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE708384X | 1951-03-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB708384A true GB708384A (en) | 1954-05-05 |
Family
ID=6617602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB6705/52A Expired GB708384A (en) | 1951-03-16 | 1952-03-14 | Drug solutions and process for the manufacture thereof |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB708384A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0120286A1 (en) * | 1983-02-22 | 1984-10-03 | The Wellcome Foundation Limited | Pesticidal pour-on oil formulations |
| FR2558729A1 (en) * | 1984-02-01 | 1985-08-02 | Nitto Electric Ind Co | COMPOSITION FOR PERCUTANEOUS ADMINISTRATION OF METOCLOPRAMIDE |
-
1952
- 1952-03-14 GB GB6705/52A patent/GB708384A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0120286A1 (en) * | 1983-02-22 | 1984-10-03 | The Wellcome Foundation Limited | Pesticidal pour-on oil formulations |
| FR2558729A1 (en) * | 1984-02-01 | 1985-08-02 | Nitto Electric Ind Co | COMPOSITION FOR PERCUTANEOUS ADMINISTRATION OF METOCLOPRAMIDE |
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