GB552581A - Process for the manufacture of pantothenic acid - Google Patents
Process for the manufacture of pantothenic acidInfo
- Publication number
- GB552581A GB552581A GB5745/41A GB574541A GB552581A GB 552581 A GB552581 A GB 552581A GB 5745/41 A GB5745/41 A GB 5745/41A GB 574541 A GB574541 A GB 574541A GB 552581 A GB552581 A GB 552581A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pantothenic acid
- aqueous solution
- sodium methoxide
- manufacture
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 title abstract 8
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 title abstract 4
- 229940055726 pantothenic acid Drugs 0.000 title abstract 4
- 235000019161 pantothenic acid Nutrition 0.000 title abstract 4
- 239000011713 pantothenic acid Substances 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- WQDUMFSSJAZKTM-UHFFFAOYSA-N Sodium methoxide Chemical compound [Na+].[O-]C WQDUMFSSJAZKTM-UHFFFAOYSA-N 0.000 abstract 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 239000007864 aqueous solution Substances 0.000 abstract 3
- 239000012670 alkaline solution Substances 0.000 abstract 1
- 159000000007 calcium salts Chemical class 0.000 abstract 1
- 235000011121 sodium hydroxide Nutrition 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
552,581. Pantothenic acid. HOFFMANLA ROCHE & CO., AKT.-GES., F. May 2, 1941, No. 5745. Convention date, April 19, 1940. [Class 2 (iii)] Pantothenic acid is prepared by reacting an alkaline solution of #-alanine with α-hydroxy- ##-dimethyl-γ-butyrolactone. In examples the reaction is carried out in the presence of (1) sodium methoxide in aqueous solution, (2) an aqueous solution of caustic soda, (3) a methyl alcohol solution of sodium methoxide, and (4) an aqueous solution of potassium hydroxide. In each case the pantothenic acid is isolated as the calcium salt. Specifications 535,988 and 551,883 are referred to.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH552581X | 1940-04-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB552581A true GB552581A (en) | 1943-04-15 |
Family
ID=4519731
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5745/41A Expired GB552581A (en) | 1940-04-19 | 1941-05-02 | Process for the manufacture of pantothenic acid |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB552581A (en) |
-
1941
- 1941-05-02 GB GB5745/41A patent/GB552581A/en not_active Expired
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