[go: up one dir, main page]

GB539893A - Improvements in the preparation of water-soluble derivatives of 2-sulfanilylamidopyridine - Google Patents

Improvements in the preparation of water-soluble derivatives of 2-sulfanilylamidopyridine

Info

Publication number
GB539893A
GB539893A GB5168/40A GB516840A GB539893A GB 539893 A GB539893 A GB 539893A GB 5168/40 A GB5168/40 A GB 5168/40A GB 516840 A GB516840 A GB 516840A GB 539893 A GB539893 A GB 539893A
Authority
GB
United Kingdom
Prior art keywords
compound
water
sodium
disodium
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5168/40A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB539893A publication Critical patent/GB539893A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/76—Nitrogen atoms to which a second hetero atom is attached

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

539,893. Sulphonamido compounds. MERCK & CO., Inc. March 20, 1940, No. 5168. Convention date, March 23, 1939. [Class 2 (iii)] 2 - p - Aminobenzenesulphonamidopyridine, described in Specification 512,145, is converted into its water-soluble N-sodium methylenesulphinate bv treatment with sodium formaldehyde-sulphoxylate in water, glycerine or an aliphatic alcohol or glycol as solvent. The water-soluble disodium compound is obtained if the starting material is used in the form of its sodium compound ; treatment of the disodium compound with mineral acid gives rise to the monosodium compound, from which the disodium compound can be regenerated with caustic soda. The free methylenesulphinic acid may be prepared from the disodium compound by treatment with acetic acid. The products are useful therapeutically. An example is given of the preparation of the monosodium compound, i.e. the N-sodium methylenesulphinate.
GB5168/40A 1939-03-23 1940-03-20 Improvements in the preparation of water-soluble derivatives of 2-sulfanilylamidopyridine Expired GB539893A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US539893XA 1939-03-23 1939-03-23

Publications (1)

Publication Number Publication Date
GB539893A true GB539893A (en) 1941-09-29

Family

ID=21987953

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5168/40A Expired GB539893A (en) 1939-03-23 1940-03-20 Improvements in the preparation of water-soluble derivatives of 2-sulfanilylamidopyridine

Country Status (1)

Country Link
GB (1) GB539893A (en)

Similar Documents

Publication Publication Date Title
GB536939A (en) Improvements in and relating to photographic colour development
GB539893A (en) Improvements in the preparation of water-soluble derivatives of 2-sulfanilylamidopyridine
GB516883A (en) Process for producing coloured photographic layers
GB515386A (en) Process for preparing germicides and products thereof
GB563991A (en) Improvements in or relating to the production of polyvinyl compounds
GB497698A (en) Improvements in or relating to colour-formers for use in colour photography
GB562269A (en) Improvements relating to the production of copolymers of divinyl sulphide and butadiene
GB582988A (en) Fire extinguishing composition
GB415472A (en) Improvements in or relating to the manufacture of oxalic acid and esters thereof
GB549800A (en) Improvement in processes and materials for thickening latex and like materials
GB529382A (en) Manufacture of derivatives of aliphatic amino-sulphonic acids
GB500607A (en) p-carbamidobenzenesulphonamide and process of producing it
GB252099A (en) Improvements in or relating to the preparation of soluble salts of substituted phenyl-arsinic acids
GB1362577A (en) Water-soluble monoazo dyestuffs and process for preparing them
GB393265A (en) Improvements relating to the production of water-free ethyl alcohol
GB547409A (en) Process for the preparation of 4-acetamido-2-hydroxyphenylarsenoxide
GB1207048A (en) Novel 2-alkyl-4-oxa-steroids and a process for the manufacture thereof
GB296106A (en) Improvements in the manufacture and production of n-dihydro-1.2.1.2 anthraquinoneazine
GB559893A (en) Process for the manufacture of pure, crystalline calcium-?-pantothenate
AT170258B (en) Process for the preparation of water-soluble sodium salts of cellulose ether acids, e.g. B. Sodium cellulose glycolate
GB515756A (en) Manufacture of ª‡-chloro-ª‰-alkoxybutyraldehydes
GB743385A (en) 8-bromotheophylline-2-amino-2-methyl-1-propanol
GR6635B (en) METHOD FOR PREPARATION B - (P - OXYPHINYL) - ISOPROPYLMETHYLAMINE.
GB292950A (en) Manufacture of n-oxyethyl derivatives of 2-amino-1-oxybenzene
GB568135A (en) Improvements in the manufacture of titanium compounds