GB395296A - Process for the manufacture of new soluble calcium salts and products obtained thereby - Google Patents
Process for the manufacture of new soluble calcium salts and products obtained therebyInfo
- Publication number
- GB395296A GB395296A GB6102/33A GB610233A GB395296A GB 395296 A GB395296 A GB 395296A GB 6102/33 A GB6102/33 A GB 6102/33A GB 610233 A GB610233 A GB 610233A GB 395296 A GB395296 A GB 395296A
- Authority
- GB
- United Kingdom
- Prior art keywords
- calcium
- salts
- hypobromite
- aqueous solution
- double
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 159000000007 calcium salts Chemical class 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 229910001622 calcium bromide Inorganic materials 0.000 abstract 4
- WGEFECGEFUFIQW-UHFFFAOYSA-L calcium dibromide Chemical compound [Ca+2].[Br-].[Br-] WGEFECGEFUFIQW-UHFFFAOYSA-L 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- 239000007864 aqueous solution Substances 0.000 abstract 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Chemical compound OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 2
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 abstract 2
- 229910001861 calcium hydroxide Inorganic materials 0.000 abstract 2
- 239000000920 calcium hydroxide Substances 0.000 abstract 2
- XVDWMONETMNKBK-UHFFFAOYSA-N calcium;dihypobromite Chemical compound [Ca+2].Br[O-].Br[O-] XVDWMONETMNKBK-UHFFFAOYSA-N 0.000 abstract 2
- 230000008020 evaporation Effects 0.000 abstract 2
- 238000001704 evaporation Methods 0.000 abstract 2
- JGJLWPGRMCADHB-UHFFFAOYSA-N hypobromite Chemical compound Br[O-] JGJLWPGRMCADHB-UHFFFAOYSA-N 0.000 abstract 2
- 239000000243 solution Substances 0.000 abstract 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- 239000002970 Calcium lactobionate Substances 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 229940050954 calcium lactobionate Drugs 0.000 abstract 1
- 235000019307 calcium lactobionate Nutrition 0.000 abstract 1
- RHEMCSSAABKPLI-SQCCMBKESA-L calcium;(2r,3r,4r,5r)-2,3,5,6-tetrahydroxy-4-[(2s,3r,4s,5r,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoate Chemical compound [Ca+2].[O-]C(=O)[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O.[O-]C(=O)[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O RHEMCSSAABKPLI-SQCCMBKESA-L 0.000 abstract 1
- JYTUSYBCFIZPBE-ZNLUKOTNSA-N cellobionic acid Chemical compound OC(=O)[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O JYTUSYBCFIZPBE-ZNLUKOTNSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Double calcium salts are prepared by treatment of calcium bromide with the calcium salts of polyhydroxymonocarboxylic acids derived from polyaldoses in equimolecular proportions. The salts are ground together or caused to react in aqueous solution. In a modification, polyaldoses are oxidized with calcium hypobromite in presence of calcium hydroxide, when the calcium bromide liberated from the hypobromite unites with the neutralized oxidation product. The double salts are useful therapeutically. According to the examples, (1) calcium bromide is ground, or dissolved in hot water, with calcium lactobionate; from its solution, it crystallizes out; (2) milk sugar is oxidized in aqueous solution with a mixture of calcium hydroxide and calcium hypobromite; on evaporation of the filtered solution, the double salt separates out; (3) from an aqueous solution of calcium bromide and calcium maltobionate, the double salt is isolated by evaporation under reduced pressure or by precipitation with alcohol.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH395296X | 1932-03-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB395296A true GB395296A (en) | 1933-07-13 |
Family
ID=4514056
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB6102/33A Expired GB395296A (en) | 1932-03-04 | 1933-02-28 | Process for the manufacture of new soluble calcium salts and products obtained thereby |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB395296A (en) |
-
1933
- 1933-02-28 GB GB6102/33A patent/GB395296A/en not_active Expired
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