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GB201120711D0 - Method for classifying tumour cells - Google Patents

Method for classifying tumour cells

Info

Publication number
GB201120711D0
GB201120711D0 GBGB1120711.5A GB201120711A GB201120711D0 GB 201120711 D0 GB201120711 D0 GB 201120711D0 GB 201120711 A GB201120711 A GB 201120711A GB 201120711 D0 GB201120711 D0 GB 201120711D0
Authority
GB
United Kingdom
Prior art keywords
classifying
tumour cells
classes
nsclc
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1120711.5A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Erasmus University Medical Center
Original Assignee
Erasmus University Medical Center
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erasmus University Medical Center filed Critical Erasmus University Medical Center
Priority to GBGB1120711.5A priority Critical patent/GB201120711D0/en
Publication of GB201120711D0 publication Critical patent/GB201120711D0/en
Priority to PCT/EP2012/004957 priority patent/WO2013079215A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G01N33/5752—
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention relates to a method for preparing an optimised gene signature for assigning a NSCLC sample to one or more NSCLC classes, comprising subjecting a gene signature set forth in Table 12 herein to nearest shrunken centroid analysis to identify one or more subgroups of gene classifiers corresponding to one or more of classes 1 to 6 identified in Table 12, and validating the performance of the selected classifiers by K-fold or leave-one-out cross-validation.
GBGB1120711.5A 2011-12-01 2011-12-01 Method for classifying tumour cells Ceased GB201120711D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB1120711.5A GB201120711D0 (en) 2011-12-01 2011-12-01 Method for classifying tumour cells
PCT/EP2012/004957 WO2013079215A1 (en) 2011-12-01 2012-11-30 Method for classifying tumour cells

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1120711.5A GB201120711D0 (en) 2011-12-01 2011-12-01 Method for classifying tumour cells

Publications (1)

Publication Number Publication Date
GB201120711D0 true GB201120711D0 (en) 2012-01-11

Family

ID=45509031

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1120711.5A Ceased GB201120711D0 (en) 2011-12-01 2011-12-01 Method for classifying tumour cells

Country Status (2)

Country Link
GB (1) GB201120711D0 (en)
WO (1) WO2013079215A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9726661B2 (en) * 2012-07-06 2017-08-08 Institut Gustave-Roussy Simultaneous detection of cannibalism and senescence as prognostic marker for cancer
WO2014018683A2 (en) * 2012-07-24 2014-01-30 Cedars-Sinai Medical Center A novel method to detect resistance to chemotherapy in patients with lung cancer
CN110662844A (en) 2017-05-22 2020-01-07 内盖夫生物技术国家研究所有限公司 Biomarkers for diagnosis of lung cancer
CN112159661B (en) * 2020-08-31 2022-09-27 南昌航空大学 Preparation method and application of rare earth upconversion fluorescent probe for detecting DNA damage markers
CN113096730B (en) * 2021-04-02 2022-02-25 中山大学 Prediction system for nasopharyngeal carcinoma molecular typing

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4631211A (en) 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5270163A (en) 1990-06-11 1993-12-14 University Research Corporation Methods for identifying nucleic acid ligands
US5567588A (en) 1990-06-11 1996-10-22 University Research Corporation Systematic evolution of ligands by exponential enrichment: Solution SELEX
US5503978A (en) 1990-06-11 1996-04-02 University Research Corporation Method for identification of high affinity DNA ligands of HIV-1 reverse transcriptase
US5654151A (en) 1990-06-11 1997-08-05 Nexstar Pharmaceuticals, Inc. High affinity HIV Nucleocapsid nucleic acid ligands
US5837832A (en) 1993-06-25 1998-11-17 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
JP4531132B2 (en) 1995-06-02 2010-08-25 ギリード・サイエンシズ・インコーポレーテッド High affinity oligonucleotide ligands for growth factors
WO1998035012A2 (en) 1997-02-12 1998-08-13 Chan Eugene Y Methods and products for analyzing polymers
US6403311B1 (en) 1997-02-12 2002-06-11 Us Genomics Methods of analyzing polymers using ordered label strategies
DE69838521T2 (en) 1997-07-07 2008-05-21 Medical Research Council Method for increasing the concentration of nucleic acid molecules
US6790671B1 (en) 1998-08-13 2004-09-14 Princeton University Optically characterizing polymers
US6263286B1 (en) 1998-08-13 2001-07-17 U.S. Genomics, Inc. Methods of analyzing polymers using a spatial network of fluorophores and fluorescence resonance energy transfer
US6210896B1 (en) 1998-08-13 2001-04-03 Us Genomics Molecular motors
GB9900298D0 (en) 1999-01-07 1999-02-24 Medical Res Council Optical sorting method
US6818395B1 (en) 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
US6440706B1 (en) 1999-08-02 2002-08-27 Johns Hopkins University Digital amplification
US6762059B2 (en) 1999-08-13 2004-07-13 U.S. Genomics, Inc. Methods and apparatuses for characterization of single polymers
US6696022B1 (en) 1999-08-13 2004-02-24 U.S. Genomics, Inc. Methods and apparatuses for stretching polymers
AU7086800A (en) 1999-08-30 2001-03-26 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The High speed parallel molecular nucleic acid sequencing
GB0022458D0 (en) 2000-09-13 2000-11-01 Medical Res Council Directed evolution method
US7194269B2 (en) 2000-10-30 2007-03-20 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Industry Method and wireless communication hub for data communications
GB0127564D0 (en) 2001-11-16 2002-01-09 Medical Res Council Emulsion compositions
CA2513535C (en) 2003-01-29 2012-06-12 454 Corporation Bead emulsion nucleic acid amplification
US8048627B2 (en) 2003-07-05 2011-11-01 The Johns Hopkins University Method and compositions for detection and enumeration of genetic variations
WO2005039389A2 (en) 2003-10-22 2005-05-06 454 Corporation Sequence-based karyotyping
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
US20060019264A1 (en) 2003-12-01 2006-01-26 Said Attiya Method for isolation of independent, parallel chemical micro-reactions using a porous filter
CA2553833C (en) 2004-01-28 2012-10-02 454 Corporation Nucleic acid amplification with continuous flow emulsion
EP1735626A2 (en) 2004-04-16 2006-12-27 EVOTEC Neurosciences GmbH Diagnostic and therapeutic use of kcnc1 for neurodegenerative diseases
US20100273711A1 (en) * 2007-09-28 2010-10-28 Anil Potti Individualized cancer treatments

Also Published As

Publication number Publication date
WO2013079215A1 (en) 2013-06-06

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)