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GB1504295A - 6 beta-fluoropregnane-compounds - Google Patents

6 beta-fluoropregnane-compounds

Info

Publication number
GB1504295A
GB1504295A GB4297877A GB4297877A GB1504295A GB 1504295 A GB1504295 A GB 1504295A GB 4297877 A GB4297877 A GB 4297877A GB 4297877 A GB4297877 A GB 4297877A GB 1504295 A GB1504295 A GB 1504295A
Authority
GB
United Kingdom
Prior art keywords
fluoro
fluoropregnane
beta
compounds
dione
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4297877A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB4297877A priority Critical patent/GB1504295A/en
Publication of GB1504295A publication Critical patent/GB1504295A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

1504295 6# - Fluoro - #<SP>1,4,9(11)</SP> - pregnatrienes G PALLADINO 24 Feb 1975 [5 March 1974] 42978/77 Divided out of 1504294 Heading C2U Novel steroids are 6#-fluoro-1,4,9(11),16-pregnatetraen- 21 - ol - 3,20 - dione 21 - acetate; 6# - fluoro - 1,4,9(11) - pregnatriene 16α,17α,21 - triol - 3,20 - dione 21-acetate; and those of the formula wherein Ac is acetyl; R is 2-8C alkanoyl; and Z is H, α-CH 3 or #-CH 3 . They are prepared as illustrated in the following reaction schemes which also illustrate their conversion to the pharmacologically active steroids of the parent Specification.
GB4297877A 1975-02-24 1975-02-24 6 beta-fluoropregnane-compounds Expired GB1504295A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB4297877A GB1504295A (en) 1975-02-24 1975-02-24 6 beta-fluoropregnane-compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4297877A GB1504295A (en) 1975-02-24 1975-02-24 6 beta-fluoropregnane-compounds

Publications (1)

Publication Number Publication Date
GB1504295A true GB1504295A (en) 1978-03-15

Family

ID=10426813

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4297877A Expired GB1504295A (en) 1975-02-24 1975-02-24 6 beta-fluoropregnane-compounds

Country Status (1)

Country Link
GB (1) GB1504295A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3250211A4 (en) * 2015-01-30 2018-09-05 Coral Drugs Pvt. Ltd. Novel process for preparation of glucocorticoid steroids

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3250211A4 (en) * 2015-01-30 2018-09-05 Coral Drugs Pvt. Ltd. Novel process for preparation of glucocorticoid steroids

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Legal Events

Date Code Title Description
PS Patent sealed
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee