GB1486787A - Process for stabilizing protein containing liquids - Google Patents
Process for stabilizing protein containing liquidsInfo
- Publication number
- GB1486787A GB1486787A GB4594774A GB4594774A GB1486787A GB 1486787 A GB1486787 A GB 1486787A GB 4594774 A GB4594774 A GB 4594774A GB 4594774 A GB4594774 A GB 4594774A GB 1486787 A GB1486787 A GB 1486787A
- Authority
- GB
- United Kingdom
- Prior art keywords
- serum
- protein
- liquid
- rabbit
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/34—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood group antigens
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Developmental Biology & Embryology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Alternative & Traditional Medicine (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Mycology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
Abstract
1486787 Stabilising protein-containing liquids BEHRINGWERKE AG 23 Oct 1974 [23 Oct 1973 6 Sept 1974] 45947/74 Heading A5B [Also in Division C3] A process for stabilising a protein-containing liquid derived from a plant or an animal, e.g. a plant or animal organ extract or serum, comprises treating the liquid with from 3 to 6% by weight, referred to the protein content of the liquid, of a water-soluble salt of an 'acridine or quinoline compound, separating the resulting precipitate, and removing any free acridine or quinoline compound still present in the resulting solution, as by adsorption on active charcoal or bentonite, The resulting stabilized liquid may be sterile filtered into ampoules and lyophilized. A stabilized human or animal serum of which at least one of the components has been determined and standardised, may be employed as a reference standard serum. Many protein-containing liquids are particularly mentioned. Preferred compounds are 2-ethoxy-6, 9-diaminoacridine lactate or bis-(2-methyl-4-amino-quinolyl-6)-carbamide hydrochloride. Contact times of 10-30 minutes are usual. Examples relate to the stabilization of the following proteincontaining liquids: anti-A-serum (human), AB- serum (human), anti-P 1 -serum (wether), antihaptoglobin serum (rabbit), anti-alpha 1 -lipoprotein serum (rabbit); anti-# 2 -glycoprotein serum (rabbit), anti-IgA-serum (sheep or goat) and an aqueous extract of Dolichos biflorus obtained according to known methods for the preparation of phytagglutinin anti-A 1 .
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19732353035 DE2353035B2 (en) | 1973-10-23 | 1973-10-23 | Process for stabilizing human or animal body fluids or plant extracts |
| DE19742442680 DE2442680A1 (en) | 1973-10-23 | 1974-09-06 | STANDARD AND CONTROLLER |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1486787A true GB1486787A (en) | 1977-09-21 |
Family
ID=25765995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4594774A Expired GB1486787A (en) | 1973-10-23 | 1974-10-23 | Process for stabilizing protein containing liquids |
Country Status (9)
| Country | Link |
|---|---|
| BE (1) | BE821384A (en) |
| DE (2) | DE2353035B2 (en) |
| DK (1) | DK138255C (en) |
| FR (1) | FR2248051B1 (en) |
| GB (1) | GB1486787A (en) |
| IE (1) | IE40074B1 (en) |
| IT (1) | IT1049321B (en) |
| LU (1) | LU71160A1 (en) |
| NL (1) | NL7413865A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9863699B2 (en) | 2014-06-09 | 2018-01-09 | Terumo Bct, Inc. | Lyophilization |
| US10793327B2 (en) | 2017-10-09 | 2020-10-06 | Terumo Bct Biotechnologies, Llc | Lyophilization container and method of using same |
| US11604026B2 (en) | 2019-03-14 | 2023-03-14 | Terumo Bct Biotechnologies, Llc | Lyophilization loading tray assembly and system |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2831390C2 (en) * | 1978-07-17 | 1980-08-14 | Boehringer Mannheim Gmbh, 6800 Mannheim | Control serum for clinical-chemical analysis with a certain content of creatine kinase |
| US4438202A (en) * | 1981-11-30 | 1984-03-20 | Technicon Instruments Corporation | Stable, base serum compositions and preparation thereof |
-
1973
- 1973-10-23 DE DE19732353035 patent/DE2353035B2/en not_active Withdrawn
-
1974
- 1974-09-06 DE DE19742442680 patent/DE2442680A1/en not_active Withdrawn
- 1974-10-21 IT IT2863074A patent/IT1049321B/en active
- 1974-10-21 IE IE215774A patent/IE40074B1/en unknown
- 1974-10-22 LU LU71160A patent/LU71160A1/xx unknown
- 1974-10-22 DK DK551474A patent/DK138255C/en not_active IP Right Cessation
- 1974-10-23 GB GB4594774A patent/GB1486787A/en not_active Expired
- 1974-10-23 NL NL7413865A patent/NL7413865A/en unknown
- 1974-10-23 BE BE149799A patent/BE821384A/en unknown
- 1974-10-23 FR FR7435603A patent/FR2248051B1/fr not_active Expired
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11137206B2 (en) | 2014-06-09 | 2021-10-05 | Terumo Bct, Inc. | Lyophilization |
| US10539367B2 (en) | 2014-06-09 | 2020-01-21 | Terumo Bct, Inc. | Lyophilization |
| US9863699B2 (en) | 2014-06-09 | 2018-01-09 | Terumo Bct, Inc. | Lyophilization |
| US10969171B2 (en) | 2014-06-09 | 2021-04-06 | Terumo Bct, Inc. | Lyophilization |
| US10976105B2 (en) | 2014-06-09 | 2021-04-13 | Terumo Bct, Inc. | Lyophilization |
| US11067336B2 (en) | 2014-06-09 | 2021-07-20 | Terumo Bct, Inc. | Lyophilization |
| US11634257B2 (en) | 2017-10-09 | 2023-04-25 | Terumo Bct Biotechnologies, Llc | Lyophilization container and method of using same |
| US10793327B2 (en) | 2017-10-09 | 2020-10-06 | Terumo Bct Biotechnologies, Llc | Lyophilization container and method of using same |
| US11609042B2 (en) | 2019-03-14 | 2023-03-21 | Terumo Bct Biotechnologies, Llc | Multi-part lyophilization container and method of use |
| US11609043B2 (en) | 2019-03-14 | 2023-03-21 | Terumo Bct Biotechnologies, Llc | Lyophilization container fill fixture, system and method of use |
| US11604026B2 (en) | 2019-03-14 | 2023-03-14 | Terumo Bct Biotechnologies, Llc | Lyophilization loading tray assembly and system |
| US11740019B2 (en) | 2019-03-14 | 2023-08-29 | Terumo Bct Biotechnologies, Llc | Lyophilization loading tray assembly and system |
| US11747082B2 (en) | 2019-03-14 | 2023-09-05 | Terumo Bct Biotechnologies, Llc | Multi-part lyophilization container and method of use |
| US11815311B2 (en) | 2019-03-14 | 2023-11-14 | Terumo Bct Biotechnologies, Llc | Lyophilization container fill fixture, system and method of use |
| US11994343B2 (en) | 2019-03-14 | 2024-05-28 | Terumo Bct Biotechnologies, Llc | Multi-part lyophilization container and method of use |
Also Published As
| Publication number | Publication date |
|---|---|
| IE40074B1 (en) | 1979-03-14 |
| DK551474A (en) | 1975-06-16 |
| IE40074L (en) | 1975-04-23 |
| LU71160A1 (en) | 1976-08-19 |
| IT1049321B (en) | 1981-01-20 |
| BE821384A (en) | 1975-04-23 |
| DK138255C (en) | 1979-01-22 |
| FR2248051A1 (en) | 1975-05-16 |
| NL7413865A (en) | 1975-04-25 |
| DK138255B (en) | 1978-08-07 |
| FR2248051B1 (en) | 1979-09-28 |
| DE2353035A1 (en) | 1975-04-30 |
| DE2442680A1 (en) | 1976-08-12 |
| DE2353035B2 (en) | 1979-10-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee | ||
| PCNP | Patent ceased through non-payment of renewal fee |