[go: up one dir, main page]

GB1368812A - Thienodiazepine compounds processes for producing them and compositions containing them - Google Patents

Thienodiazepine compounds processes for producing them and compositions containing them

Info

Publication number
GB1368812A
GB1368812A GB5289171A GB5289171A GB1368812A GB 1368812 A GB1368812 A GB 1368812A GB 5289171 A GB5289171 A GB 5289171A GB 5289171 A GB5289171 A GB 5289171A GB 1368812 A GB1368812 A GB 1368812A
Authority
GB
United Kingdom
Prior art keywords
alkyl
formula
producing
nov
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5289171A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1149571A external-priority patent/JPS5010871B1/ja
Priority claimed from JP1149471A external-priority patent/JPS4941437B1/ja
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Publication of GB1368812A publication Critical patent/GB1368812A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/36—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1368812 Thienodiazepines SUMITOMO CHEMICAL CO Ltd 15 Nov 1971 [16 Nov 1970 15 Dec 1970 2 March 1971 (2)] 52891/71 Heading C2C Compounds of the general formula (R 1 = H, C 1-4 alkyl, cycloalkylmethyl, (CH 2 ) n - NR A R B , CH 2 CONR C R D , (CH 2 ) n OR E ; R A-E = H, C 1-4 alkyl; n = 1-4; R 2 = H, C 1-4 alkyl; R 3 = H, halogen; X = halogen, NO 2 , CN, C 1-4 alkyl or alkoxy) and their acid addition salts are prepared by (a) cyclizing a compound of the formula or salt thereof or (b) reacting a compound of the formula (R 4 = R 1 except H) with hydrazine hydrate, optionally followed by introduction of R 3 , R I and/or salt formation. The preparation of starting materials for both processes and of 2-bromoacetamido-3-(o-chloro- and fluorobenzoyl)thiophene is described. The above compounds are anticonvulsants, sedatives, muscle relaxants and hypnotics, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier. Reference has been directed by the Comptroller to Specification 1,291,684.
GB5289171A 1970-11-16 1971-11-15 Thienodiazepine compounds processes for producing them and compositions containing them Expired GB1368812A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP10133070 1970-11-16
JP11277370 1970-12-15
JP1149571A JPS5010871B1 (en) 1971-03-02 1971-03-02
JP1149471A JPS4941437B1 (en) 1971-03-02 1971-03-02

Publications (1)

Publication Number Publication Date
GB1368812A true GB1368812A (en) 1974-10-02

Family

ID=27455610

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5289171A Expired GB1368812A (en) 1970-11-16 1971-11-15 Thienodiazepine compounds processes for producing them and compositions containing them

Country Status (8)

Country Link
BE (1) BE775334A (en)
DD (1) DD95387A5 (en)
FI (1) FI53214C (en)
FR (1) FR2113955B1 (en)
GB (1) GB1368812A (en)
NL (1) NL7115664A (en)
NO (1) NO133672C (en)
SE (1) SE391523B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2385721A1 (en) * 1977-03-31 1978-10-27 Hexachimie CYCLOPROPYL-6 DIHYDRO-1,3 METHYL-1 PHENYL-5 OXO-2 2 H-THIENO (2,3-E) DIAZEPINE, ITS PREPARATION PROCESS AND ITS THERAPEUTIC APPLICATION

Also Published As

Publication number Publication date
FR2113955B1 (en) 1975-06-06
NO133672B (en) 1976-03-01
FI53214B (en) 1977-11-30
SE391523B (en) 1977-02-21
NL7115664A (en) 1972-05-18
BE775334A (en) 1972-03-16
DD95387A5 (en) 1973-02-05
DE2155403B2 (en) 1976-01-29
FR2113955A1 (en) 1972-06-30
NO133672C (en) 1976-06-09
DE2155403A1 (en) 1972-05-25
FI53214C (en) 1978-03-10

Similar Documents

Publication Publication Date Title
GB1374823A (en) Triazolylbenzophenones
GB1409693A (en) Triazolobenzodiazepines
GB1291631A (en) Triazolobenzodiazepine derivatives
GB1389436A (en) 1,4-benzodiazepine derivatives and their preparation
GB1456627A (en) Pyridobenzodiazepinones
GB1399230A (en) Pyrazolodiazepine compounds and methods for their production
GB1434805A (en) 5-phenoxy-4-amino pyrimidines
GB1368812A (en) Thienodiazepine compounds processes for producing them and compositions containing them
GB1243953A (en) Benzdiazepine derivatives
GB1302353A (en)
GB1449426A (en) Phenoxyalkylamine derivatives and preparation therof
GB1332697A (en) Benzodiazepine derivatives
GB1225677A (en)
GB1373271A (en) Indoles
GB1451389A (en) Indolobenzazepines
GB1260857A (en) IMIDAZO-3H-(4,5-b)-PYRIDINE DERIVATIVES
GB1323591A (en) Benzodiazepine derivatives
GB1324579A (en) N-substituted 3-aminoalkoxy-6-hydrazinopyridazines having antihypertensive activity and their preparation
GB1378617A (en) Triazolylbenzophenones
GB1352490A (en) Thiatriazolobenzo diazepines
GB1359223A (en) Benzodiazepine derivatives processes for producing them 'and compositions containing them
GB1470748A (en) 6-2-pyridyl-4h-s-triazolo-4,3-a-1,4-benzodiazepines
GB1307475A (en) Benzodiazepines process for producing them and compositions con taining them
GB1390602A (en) Benzodiazepine derivatives
GB1264128A (en)

Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee