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GB1292170A - A method of preparing aeruginoic acid and esters thereof - Google Patents

A method of preparing aeruginoic acid and esters thereof

Info

Publication number
GB1292170A
GB1292170A GB4454370A GB4454370A GB1292170A GB 1292170 A GB1292170 A GB 1292170A GB 4454370 A GB4454370 A GB 4454370A GB 4454370 A GB4454370 A GB 4454370A GB 1292170 A GB1292170 A GB 1292170A
Authority
GB
United Kingdom
Prior art keywords
esters
acid
aeruginoic
preparing
sept
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4454370A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Godo Shusei KK
Original Assignee
Godo Shusei KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Godo Shusei KK filed Critical Godo Shusei KK
Publication of GB1292170A publication Critical patent/GB1292170A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1292170 Thiazole derivatives GODO SHUSEI KK 17 Sept 1970 [17 Sept 1969] 44543/70 Addition to 1292169 Headings C2A and C2C Novel esters of 2-(o-hydroxyphenyl)-thiazole- 4-carboxylic acid are prepared by reacting ohydroxythiobenzamide with the appropriate esters of halopyruvic acids of the formula wherein X is halogen and R is an organic radical derived by the removal of a hydrogen atom of an alcoholic hydroxy group from an organic compound. The resulting ester may be hydrolysed to the free acid.
GB4454370A 1969-09-17 1970-09-17 A method of preparing aeruginoic acid and esters thereof Expired GB1292170A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7325169 1969-09-17

Publications (1)

Publication Number Publication Date
GB1292170A true GB1292170A (en) 1972-10-11

Family

ID=13512759

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4454370A Expired GB1292170A (en) 1969-09-17 1970-09-17 A method of preparing aeruginoic acid and esters thereof

Country Status (5)

Country Link
DE (1) DE2045818A1 (en)
FR (1) FR2062210A5 (en)
GB (1) GB1292170A (en)
IT (1) IT1050117B (en)
NL (1) NL7013787A (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4457936A (en) * 1980-01-29 1984-07-03 Hoechst Aktiengesellschaft Use of hydroxyphenyl-thiazole-, -thiazoline- and -thiazolidine-carboxylic acids, for influencing the collagen metabolism
EP1143951A3 (en) * 1998-09-21 2002-02-06 University Of Florida Research Foundation, Inc. Antimalarial agents
US6521652B1 (en) 1998-08-31 2003-02-18 University Of Florida Research Foundation, Inc. Thiazoline acid derivatives
US6794515B2 (en) 2002-05-15 2004-09-21 Genzyme Corporation Synthesis of 2-alkylcysteine via substituted thiazoline amide
US8278458B2 (en) 2005-04-04 2012-10-02 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues
US8324397B2 (en) 2007-03-15 2012-12-04 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues
US8604216B2 (en) 2003-09-09 2013-12-10 University Of Florida Research Foundation, Inc. Desferrithiocin derivatives and methods of use thereof
US10010535B2 (en) 2013-11-22 2018-07-03 University Of Florida Research Foundation, Incorporated Desferrithiocin analogs and uses thereof
US10570104B2 (en) 2015-04-27 2020-02-25 University Of Florida Research Foundation, Incorporated Metabolically programmed metal chelators and uses thereof
US11931346B2 (en) 2011-12-16 2024-03-19 University Of Florida Research Foundation, Incorporated Uses of 4′-desferrithiocin analogs

Cited By (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4457936A (en) * 1980-01-29 1984-07-03 Hoechst Aktiengesellschaft Use of hydroxyphenyl-thiazole-, -thiazoline- and -thiazolidine-carboxylic acids, for influencing the collagen metabolism
USRE39132E1 (en) 1998-08-31 2006-06-13 University Of Florida, Research Foundation, Inc. Thiazoline acid derivatives
US6521652B1 (en) 1998-08-31 2003-02-18 University Of Florida Research Foundation, Inc. Thiazoline acid derivatives
US6525080B1 (en) 1998-08-31 2003-02-25 University Of Florida Research Foundation, Inc. Thiazoline acid derivatives
US6559315B1 (en) 1998-08-31 2003-05-06 University Of Florida Research Foundation, Inc. Thiazoline acid derivatives
US8008502B2 (en) 1998-08-31 2011-08-30 University Of Florida Research Foundation, Inc. Thiazoline acid derivatives
US7126004B2 (en) 1998-08-31 2006-10-24 University Of Florida Research Foundation, Inc. Thiazoline acid derivatives
EP1143951A3 (en) * 1998-09-21 2002-02-06 University Of Florida Research Foundation, Inc. Antimalarial agents
US7879886B2 (en) 1998-09-21 2011-02-01 University Of Florida Research Foundation, Inc. Iron binding agents
US7144904B2 (en) 1998-09-21 2006-12-05 University Of Florida Research Foundation, Inc. Iron binding agents
US6864270B2 (en) 1998-09-21 2005-03-08 University Of Florida Research Foundation, Inc. Iron binding agents
US6875883B2 (en) 2002-05-15 2005-04-05 Genzyme Corporation Synthesis of benzonitriles from substituted benzaldehyde
US6794515B2 (en) 2002-05-15 2004-09-21 Genzyme Corporation Synthesis of 2-alkylcysteine via substituted thiazoline amide
US7002036B2 (en) 2002-05-15 2006-02-21 Genzyme Corporation Synthesis of 2-alkyl amino acids
US7038073B2 (en) 2002-05-15 2006-05-02 Genzyme Corporation Synthesis of 2-alkyl amino acids
US6903220B2 (en) 2002-05-15 2005-06-07 Genzyme Corporation Synthesis of chiral 2-alkyl amino acids
US7115769B2 (en) 2002-05-15 2006-10-03 Genzyme Corporation Synthesis of 2-alkylcysteine via phase transfer catalysis
US6875882B2 (en) 2002-05-15 2005-04-05 Genzyme Corporation Synthesis of benzonitriles from substituted benzoic acid
US6861532B2 (en) 2002-05-15 2005-03-01 Genzyme Corporation Synthesis of 2-alkylcysteine
US7285676B2 (en) 2002-05-15 2007-10-23 Genzyme Corporation Synthesis of chiral 2-alkyl amino acids
US7285670B2 (en) 2002-05-15 2007-10-23 Genzyme Corporation Synthesis of substituted thiazoline carboxylic acids
US7294718B2 (en) 2002-05-15 2007-11-13 Genzyme Corporation Synthesis of a 4-methylthiazole-4(S)-carboxylic acid compound
US7576234B2 (en) 2002-05-15 2009-08-18 Genzyme Corporation Synthesis of 2-alkyl amino acids
US6846958B2 (en) 2002-05-15 2005-01-25 Genzyme Corporation Synthesis of benzimidate from benzoic acid
US6982335B2 (en) 2002-05-15 2006-01-03 Genzyme Corporation Synthesis of substituted thiazoline carboxylic acids
US8604216B2 (en) 2003-09-09 2013-12-10 University Of Florida Research Foundation, Inc. Desferrithiocin derivatives and methods of use thereof
US8278458B2 (en) 2005-04-04 2012-10-02 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues
US8722899B2 (en) 2005-04-04 2014-05-13 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues
US9096553B2 (en) 2005-04-04 2015-08-04 University Of Florida Research Foundation, Incorporated Desferrithiocin polyether analogues
US9567309B2 (en) 2005-04-04 2017-02-14 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues
US9994535B2 (en) 2005-04-04 2018-06-12 University Of Florida Foundation, Inc. Desferrithiocin polyether analogues
US8324397B2 (en) 2007-03-15 2012-12-04 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues
US9174948B2 (en) 2007-03-15 2015-11-03 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues
US9730917B2 (en) 2007-03-15 2017-08-15 University Of Florida Research Foundation, Incorporated Desferrithiocin polyether analogues
US11931346B2 (en) 2011-12-16 2024-03-19 University Of Florida Research Foundation, Incorporated Uses of 4′-desferrithiocin analogs
US10010535B2 (en) 2013-11-22 2018-07-03 University Of Florida Research Foundation, Incorporated Desferrithiocin analogs and uses thereof
US10570104B2 (en) 2015-04-27 2020-02-25 University Of Florida Research Foundation, Incorporated Metabolically programmed metal chelators and uses thereof

Also Published As

Publication number Publication date
NL7013787A (en) 1971-03-19
IT1050117B (en) 1981-03-10
FR2062210A5 (en) 1971-06-25
DE2045818A1 (en) 1971-04-08

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees