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GB1283273A - Process and apparatus for blood fractionation - Google Patents

Process and apparatus for blood fractionation

Info

Publication number
GB1283273A
GB1283273A GB52788/70A GB5278870A GB1283273A GB 1283273 A GB1283273 A GB 1283273A GB 52788/70 A GB52788/70 A GB 52788/70A GB 5278870 A GB5278870 A GB 5278870A GB 1283273 A GB1283273 A GB 1283273A
Authority
GB
United Kingdom
Prior art keywords
blood
membrane
pressure applied
filter
pressure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB52788/70A
Inventor
William Fred Blatt
Edward Alan Agranat
Peter Nicholas Rigopulos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amicon Corp
Original Assignee
Amicon Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amicon Corp filed Critical Amicon Corp
Priority to GB52788/70A priority Critical patent/GB1283273A/en
Publication of GB1283273A publication Critical patent/GB1283273A/en
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/18—Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/147—Microfiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/08—Flat membrane modules
    • B01D63/087—Single membrane modules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/56—Labware specially adapted for transferring fluids
    • B01L3/563—Joints or fittings ; Separable fluid transfer means to transfer fluids between at least two containers, e.g. connectors
    • B01L3/5635—Joints or fittings ; Separable fluid transfer means to transfer fluids between at least two containers, e.g. connectors connecting two containers face to face, e.g. comprising a filter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
    • A61M1/3633—Blood component filters, e.g. leukocyte filters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2315/00—Details relating to the membrane module operation
    • B01D2315/10—Cross-flow filtration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons

Landscapes

  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • External Artificial Organs (AREA)

Abstract

1283273 Fractionating blood; filter for blood AMICON CORP 5 Nov 1970 52788/70 Headings BID and B1X [Also in Division Fl] Blood is separated into a cellular fraction and plasma by conducting it under pressure along a flow path in contact with a porous filter membrane having effective pore diameters of from 0.1 to 0.8 micron. The depth of the path relative to the membrane is no more than 20 mils and the pressure applied to the blood is sufficient to maintain a pressure differential between the opposite faces of the membrane of from 1 to 15 p.s.i. and a flow velocity of whole blood over the membrane of from 2 to 50 feet per minute. Two apparatus for carrying out the process are also described. In that of Figs. 3, 4 (not shown) blood from a hypodermic syringe is forced through the membrane under controlled pressure applied by spring (72).
GB52788/70A 1970-11-05 1970-11-05 Process and apparatus for blood fractionation Expired GB1283273A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB52788/70A GB1283273A (en) 1970-11-05 1970-11-05 Process and apparatus for blood fractionation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB52788/70A GB1283273A (en) 1970-11-05 1970-11-05 Process and apparatus for blood fractionation

Publications (1)

Publication Number Publication Date
GB1283273A true GB1283273A (en) 1972-07-26

Family

ID=10465321

Family Applications (1)

Application Number Title Priority Date Filing Date
GB52788/70A Expired GB1283273A (en) 1970-11-05 1970-11-05 Process and apparatus for blood fractionation

Country Status (1)

Country Link
GB (1) GB1283273A (en)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2136314A (en) * 1983-03-14 1984-09-19 Gelman Sciences Inc Filter and Method for Obtaining Blood Plasma Samples
US4631130A (en) * 1980-09-25 1986-12-23 Terumo Corporation Plasma separator
USRE32874E (en) * 1982-11-01 1989-02-21 Gail A. Rock Plasma-free medium for platelet storage
US4828976A (en) * 1983-12-29 1989-05-09 Thomas Jefferson University Glucose free media for storing blood platelets
US5034135A (en) * 1982-12-13 1991-07-23 William F. McLaughlin Blood fractionation system and method
US6863821B2 (en) 2002-02-02 2005-03-08 Baxter International Inc. Shear-enhanced systems and methods for removing waste materials and liquid from the blood
WO2011155897A1 (en) * 2010-06-10 2011-12-15 Hemcheck Sweden Aktiebolag Arrangement for detection of hemolysis
WO2013085462A1 (en) * 2011-12-09 2013-06-13 Hemcheck Sweden Aktiebolag Arrangement for detection of hemolysis
WO2015014934A1 (en) * 2013-07-31 2015-02-05 Mann+Hummel Gmbh Device for cross flow filtration
US8961789B2 (en) 2008-10-31 2015-02-24 Baxter International Inc. Systems and methods for performing hemodialysis
EP3056276A3 (en) * 2015-02-11 2016-11-16 EMD Millipore Corporation Stirred cell and method of using same
USD804653S1 (en) 2015-06-12 2017-12-05 Emd Millipore Corporation Pressure vessel
WO2017220159A1 (en) * 2016-06-24 2017-12-28 Ritter Gmbh System and method for obtaining serum from blood

Cited By (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4631130A (en) * 1980-09-25 1986-12-23 Terumo Corporation Plasma separator
USRE32874E (en) * 1982-11-01 1989-02-21 Gail A. Rock Plasma-free medium for platelet storage
US5034135A (en) * 1982-12-13 1991-07-23 William F. McLaughlin Blood fractionation system and method
US5376263A (en) * 1982-12-13 1994-12-27 William F. McLaughlin Pump control apparatus for cellular filtration systems employing rotating microporous membranes
US5464534A (en) * 1982-12-13 1995-11-07 William F. McLaughlin Blood fractionation system and method
US5783085A (en) * 1982-12-13 1998-07-21 Estate Of William F. Mclaughlin Blood fractionation method
GB2136314A (en) * 1983-03-14 1984-09-19 Gelman Sciences Inc Filter and Method for Obtaining Blood Plasma Samples
US4828976A (en) * 1983-12-29 1989-05-09 Thomas Jefferson University Glucose free media for storing blood platelets
US6863821B2 (en) 2002-02-02 2005-03-08 Baxter International Inc. Shear-enhanced systems and methods for removing waste materials and liquid from the blood
US7182867B2 (en) 2002-02-02 2007-02-27 Baxter International Inc. Shear-enhanced systems and methods for removing waste materials and liquid from the blood
US7494591B2 (en) 2002-02-02 2009-02-24 Baxter International Inc. Shear-enhanced systems and methods for removing waste materials and liquid from the blood
US9757504B2 (en) 2008-10-31 2017-09-12 Baxter International Inc. Systems and methods for performing hemodialysis
US8961789B2 (en) 2008-10-31 2015-02-24 Baxter International Inc. Systems and methods for performing hemodialysis
WO2011155897A1 (en) * 2010-06-10 2011-12-15 Hemcheck Sweden Aktiebolag Arrangement for detection of hemolysis
US8846333B2 (en) 2010-06-10 2014-09-30 Hemcheck Sweden Ab Method and device for visual detection of hemolysis
WO2013085462A1 (en) * 2011-12-09 2013-06-13 Hemcheck Sweden Aktiebolag Arrangement for detection of hemolysis
US9983199B2 (en) 2011-12-09 2018-05-29 Hemcheck Sweden Aktiebolag Arrangement for detection of hemolysis
CN105263540B (en) * 2013-07-31 2018-07-03 曼·胡默尔有限公司 For the equipment of cross-flow filtration
CN105263540A (en) * 2013-07-31 2016-01-20 曼·胡默尔有限公司 Device for cross flow filtration
US10687750B2 (en) 2013-07-31 2020-06-23 Mann+ Hummel Gmbh Device for cross flow filtration
CN108771775A (en) * 2013-07-31 2018-11-09 曼·胡默尔有限公司 equipment for cross-flow filtration
WO2015014934A1 (en) * 2013-07-31 2015-02-05 Mann+Hummel Gmbh Device for cross flow filtration
US10088398B2 (en) 2015-02-11 2018-10-02 Emd Millipore Corporation Stirred cell and method of using same
US10656060B2 (en) 2015-02-11 2020-05-19 Emd Millipore Corporation Stirred cell and method of using same
EP3056276A3 (en) * 2015-02-11 2016-11-16 EMD Millipore Corporation Stirred cell and method of using same
USD804653S1 (en) 2015-06-12 2017-12-05 Emd Millipore Corporation Pressure vessel
WO2017220159A1 (en) * 2016-06-24 2017-12-28 Ritter Gmbh System and method for obtaining serum from blood

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Legal Events

Date Code Title Description
PS Patent sealed
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PE20 Patent expired after termination of 20 years