GB1235590A - Vitamin compositions and a process for the manufacture thereof - Google Patents
Vitamin compositions and a process for the manufacture thereofInfo
- Publication number
- GB1235590A GB1235590A GB31202/69A GB3120269A GB1235590A GB 1235590 A GB1235590 A GB 1235590A GB 31202/69 A GB31202/69 A GB 31202/69A GB 3120269 A GB3120269 A GB 3120269A GB 1235590 A GB1235590 A GB 1235590A
- Authority
- GB
- United Kingdom
- Prior art keywords
- vitamin
- emulsion
- added
- june
- microns
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229940088594 vitamin Drugs 0.000 title 1
- 229930003231 vitamin Natural products 0.000 title 1
- 235000013343 vitamin Nutrition 0.000 title 1
- 239000011782 vitamin Substances 0.000 title 1
- 150000003722 vitamin derivatives Chemical class 0.000 title 1
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 abstract 6
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 abstract 6
- 235000019155 vitamin A Nutrition 0.000 abstract 6
- 239000011719 vitamin A Substances 0.000 abstract 6
- 229940045997 vitamin a Drugs 0.000 abstract 6
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 abstract 5
- 239000000839 emulsion Substances 0.000 abstract 5
- 108010010803 Gelatin Proteins 0.000 abstract 2
- 239000003963 antioxidant agent Substances 0.000 abstract 2
- 230000003078 antioxidant effect Effects 0.000 abstract 2
- 235000006708 antioxidants Nutrition 0.000 abstract 2
- 239000003995 emulsifying agent Substances 0.000 abstract 2
- 229920000159 gelatin Polymers 0.000 abstract 2
- 239000008273 gelatin Substances 0.000 abstract 2
- 235000019322 gelatine Nutrition 0.000 abstract 2
- 235000011852 gelatine desserts Nutrition 0.000 abstract 2
- 244000215068 Acacia senegal Species 0.000 abstract 1
- 235000006491 Acacia senegal Nutrition 0.000 abstract 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 abstract 1
- 239000004255 Butylated hydroxyanisole Substances 0.000 abstract 1
- 239000004322 Butylated hydroxytoluene Substances 0.000 abstract 1
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 abstract 1
- 229920000084 Gum arabic Polymers 0.000 abstract 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
- 229930006000 Sucrose Natural products 0.000 abstract 1
- -1 Vitamin A compound Chemical class 0.000 abstract 1
- 235000010489 acacia gum Nutrition 0.000 abstract 1
- 235000019282 butylated hydroxyanisole Nutrition 0.000 abstract 1
- CZBZUDVBLSSABA-UHFFFAOYSA-N butylated hydroxyanisole Chemical compound COC1=CC=C(O)C(C(C)(C)C)=C1.COC1=CC=C(O)C=C1C(C)(C)C CZBZUDVBLSSABA-UHFFFAOYSA-N 0.000 abstract 1
- 229940043253 butylated hydroxyanisole Drugs 0.000 abstract 1
- 235000010354 butylated hydroxytoluene Nutrition 0.000 abstract 1
- 229940095259 butylated hydroxytoluene Drugs 0.000 abstract 1
- 235000019864 coconut oil Nutrition 0.000 abstract 1
- 239000003240 coconut oil Substances 0.000 abstract 1
- 230000001804 emulsifying effect Effects 0.000 abstract 1
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 abstract 1
- IPCSVZSSVZVIGE-UHFFFAOYSA-M hexadecanoate Chemical compound CCCCCCCCCCCCCCCC([O-])=O IPCSVZSSVZVIGE-UHFFFAOYSA-M 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 239000003921 oil Substances 0.000 abstract 1
- 235000019198 oils Nutrition 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 229960000342 retinol acetate Drugs 0.000 abstract 1
- QGNJRVVDBSJHIZ-QHLGVNSISA-N retinyl acetate Chemical compound CC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C QGNJRVVDBSJHIZ-QHLGVNSISA-N 0.000 abstract 1
- 235000019173 retinyl acetate Nutrition 0.000 abstract 1
- 239000011770 retinyl acetate Substances 0.000 abstract 1
- 229940108325 retinyl palmitate Drugs 0.000 abstract 1
- 235000019172 retinyl palmitate Nutrition 0.000 abstract 1
- 239000011769 retinyl palmitate Substances 0.000 abstract 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 abstract 1
- 235000010234 sodium benzoate Nutrition 0.000 abstract 1
- 239000004299 sodium benzoate Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 235000010199 sorbic acid Nutrition 0.000 abstract 1
- 239000004334 sorbic acid Substances 0.000 abstract 1
- 229940075582 sorbic acid Drugs 0.000 abstract 1
- 238000001694 spray drying Methods 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
- 239000005720 sucrose Substances 0.000 abstract 1
- 229930003799 tocopherol Natural products 0.000 abstract 1
- 239000011732 tocopherol Substances 0.000 abstract 1
- 235000019149 tocopherols Nutrition 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L7/00—Cereal-derived products; Malt products; Preparation or treatment thereof
- A23L7/10—Cereal-derived products
- A23L7/101—Addition of antibiotics, vitamins, amino-acids, or minerals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
1,235,590. Stabilizing Vitamin A. F. HOFFMANN-LA ROCHE & CO. A.G. 20 June, 1969 [24 June, 1968], No. 31202/69. Heading C2V. [Also in Division A5] Vitamin A is stabilized by emulsifying (a) from 100,000 to 400,000 International Units of Vitamin A per gram of the emulsion, (b) from 50 to 120 mg. of an antioxidant per million International Units of Vitamin A, (c) from 50 to 60% by weight of the emulsion of an emulsifying agent, and (d) sufficient water to provide an emulsion containing 45% solids, the emulsion oil droplets so obtained being from 1 to 3 microns in size, and spray-drying the emulsion to obtain stabilized Vitamin A in powder form having a particle size of from 1 to 80 microns. The Vitamin A compound used may be Vitamin A acetate or palmitate and the antioxidant may be butylated hydroxy toluene, butylated hydroxy anisole or tocopherols. The emulsifying agent may be gum acacia, gelatin or hydrolysed gelatin. Coconut oil may be added as a taste stabilizer, lactose or sucrose may be added as a plasticizer-carrier and sodium benzoate and sorbic acid may be added as preservatives. Examples are given.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73920368A | 1968-06-24 | 1968-06-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1235590A true GB1235590A (en) | 1971-06-16 |
Family
ID=24971254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB31202/69A Expired GB1235590A (en) | 1968-06-24 | 1969-06-20 | Vitamin compositions and a process for the manufacture thereof |
Country Status (10)
| Country | Link |
|---|---|
| BE (1) | BE734970A (en) |
| CA (1) | CA941740A (en) |
| CH (1) | CH526274A (en) |
| DE (1) | DE1931439A1 (en) |
| DK (1) | DK127164B (en) |
| FR (1) | FR2011564A1 (en) |
| GB (1) | GB1235590A (en) |
| IT (1) | IT961359B (en) |
| NL (1) | NL6909567A (en) |
| SE (1) | SE371744B (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2897119A (en) * | 1957-11-12 | 1959-07-28 | Camp Sea Food Company Inc Van | Stable powdered oil soluble vitamins and method of preparing stable powdered oil soluble vitamins |
| DE1517044A1 (en) * | 1962-06-04 | 1969-05-14 | Hoffmann La Roche | Process for the vitaminization of food and feed |
-
1969
- 1969-06-19 CH CH935469A patent/CH526274A/en not_active IP Right Cessation
- 1969-06-19 CA CA054,755A patent/CA941740A/en not_active Expired
- 1969-06-20 GB GB31202/69A patent/GB1235590A/en not_active Expired
- 1969-06-20 DE DE19691931439 patent/DE1931439A1/en active Pending
- 1969-06-23 NL NL6909567A patent/NL6909567A/xx unknown
- 1969-06-23 DK DK336169AA patent/DK127164B/en unknown
- 1969-06-23 BE BE734970A patent/BE734970A/en unknown
- 1969-06-23 FR FR6920921A patent/FR2011564A1/fr not_active Withdrawn
- 1969-06-24 IT IT18639/69A patent/IT961359B/en active
- 1969-06-24 SE SE6908496A patent/SE371744B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK127164B (en) | 1973-10-01 |
| CA941740A (en) | 1974-02-12 |
| IT961359B (en) | 1973-12-10 |
| DE1931439A1 (en) | 1970-01-15 |
| FR2011564A1 (en) | 1970-03-06 |
| NL6909567A (en) | 1969-12-30 |
| CH526274A (en) | 1972-08-15 |
| BE734970A (en) | 1969-12-23 |
| SE371744B (en) | 1974-12-02 |
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