GB1196595A - Preparation of a Lactone - Google Patents
Preparation of a LactoneInfo
- Publication number
- GB1196595A GB1196595A GB2151268A GB2151268A GB1196595A GB 1196595 A GB1196595 A GB 1196595A GB 2151268 A GB2151268 A GB 2151268A GB 2151268 A GB2151268 A GB 2151268A GB 1196595 A GB1196595 A GB 1196595A
- Authority
- GB
- United Kingdom
- Prior art keywords
- lactone
- hydroxy
- formula
- preparation
- decanedioic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002596 lactones Chemical class 0.000 title 1
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 abstract 1
- OWYWGLHRNBIFJP-UHFFFAOYSA-N Ipazine Chemical compound CCN(CC)C1=NC(Cl)=NC(NC(C)C)=N1 OWYWGLHRNBIFJP-UHFFFAOYSA-N 0.000 abstract 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 150000002762 monocarboxylic acid derivatives Chemical class 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 238000006385 ozonation reaction Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1,196,595. 6-hydroxy-1,10-decanedioic acid- 1,6-lactone. GEIGY (U.K.) Ltd. 23 Nov., 1967 [21 Dec., 1966], No. 21512/68. Divided out of 1,196,594. Heading C2C. 6-hydroxy-1,10-decanedioic acid-1,6-lactone, having the formula is prepared by treating 1,6-oxido-cyclodec-1-ene, having the formula with ozone, and thermally oxidizing the ozonized material at an elevated temperature. The ozonization is preferably carried out in the presence of a solvent consisting of an aliphatic alcohol or a monocarboxylic acid having from 1 to 4 carbon atoms.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2151268A GB1196595A (en) | 1966-12-21 | 1966-12-21 | Preparation of a Lactone |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2151268A GB1196595A (en) | 1966-12-21 | 1966-12-21 | Preparation of a Lactone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1196595A true GB1196595A (en) | 1970-07-01 |
Family
ID=10164186
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2151268A Expired GB1196595A (en) | 1966-12-21 | 1966-12-21 | Preparation of a Lactone |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1196595A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7119221B2 (en) | 2003-01-23 | 2006-10-10 | Esperion Therapeutics, Inc. | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses |
| US10912751B2 (en) | 2015-03-13 | 2021-02-09 | Esperion Therapeutics, Inc. | Fixed dose combinations and formulations comprising ETC1002 and ezetimibe and methods of treating or reducing the risk of cardiovascular disease |
| US11116739B2 (en) | 2015-03-16 | 2021-09-14 | Esperion Therapeutics, Inc. | Fixed dose combinations and formulations comprising ETC1002 and one or more statins and methods of treating or reducing cardiovascular disease |
| US11407705B2 (en) | 2019-06-21 | 2022-08-09 | Esperion Therapeutics, Inc. | Methods of making bempedoic acid and compositions of the same |
-
1966
- 1966-12-21 GB GB2151268A patent/GB1196595A/en not_active Expired
Cited By (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9452964B2 (en) | 2003-01-23 | 2016-09-27 | Esperion Therapeutics, Inc. | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses |
| US10047028B2 (en) | 2003-01-23 | 2018-08-14 | Esperion Therapeutics, Inc. | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses |
| US7335689B2 (en) | 2003-01-23 | 2008-02-26 | Esperion Therapeutics, Inc. | Dihydroxyl compounds and compositions for cholesterol management and related uses |
| US7405226B2 (en) | 2003-01-23 | 2008-07-29 | Pfizer Inc. | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses |
| US7576130B2 (en) | 2003-01-23 | 2009-08-18 | Esperion Therapeutics, Inc. | Dihydroxyl compounds and compositions for cholesterol management and related uses |
| US7812199B2 (en) | 2003-01-23 | 2010-10-12 | Esperion Therapeutics, Inc. | Hydroxyl compounds and compositions for cholesterol management and related uses |
| US7838554B2 (en) | 2003-01-23 | 2010-11-23 | Esperion Therapeutics, Inc. | Dihydroxyl compounds and compositions for cholesterol management and related uses |
| US8067466B2 (en) | 2003-01-23 | 2011-11-29 | Esperion Therapeutics, Inc. | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management |
| US8153690B2 (en) | 2003-01-23 | 2012-04-10 | Esperion Therapeutics, Inc. | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management |
| US8309604B2 (en) | 2003-01-23 | 2012-11-13 | Esperion Therapeutics, Inc. | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses |
| US8497301B2 (en) | 2003-01-23 | 2013-07-30 | Esperion Therapeutics, Inc. | Hydroxyl compounds and compositions for cholesterol management and related uses |
| US8623915B2 (en) | 2003-01-23 | 2014-01-07 | Esperion Therapeutics, Inc. | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses |
| US9000041B2 (en) | 2003-01-23 | 2015-04-07 | Esperion Therapeutics, Inc. | Hydroxyl compounds and compositions for cholesterol management and related uses |
| US9006290B2 (en) | 2003-01-23 | 2015-04-14 | Esperion Therapeutics, Inc. | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses |
| US7335799B2 (en) | 2003-01-23 | 2008-02-26 | Esperion Therapeutics, Inc. | Hydroxyl compounds and compositions for cholesterol management and related uses |
| US7119221B2 (en) | 2003-01-23 | 2006-10-10 | Esperion Therapeutics, Inc. | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses |
| US9624152B2 (en) | 2003-01-23 | 2017-04-18 | Esperion Therapeutics, Inc. | Hydroxyl compounds and compositions for cholesterol management and related uses |
| US10118881B2 (en) | 2003-01-23 | 2018-11-06 | Esperion Therapeutics, Inc. | Hydroxyl compounds and compositions for cholesterol management and related uses |
| US10941095B2 (en) | 2003-01-23 | 2021-03-09 | Esperion Therapeutics, Inc. | Hydroxyl compounds and compositions for cholesterol management and related uses |
| US10912751B2 (en) | 2015-03-13 | 2021-02-09 | Esperion Therapeutics, Inc. | Fixed dose combinations and formulations comprising ETC1002 and ezetimibe and methods of treating or reducing the risk of cardiovascular disease |
| US11744816B2 (en) | 2015-03-13 | 2023-09-05 | Esperion Therapeutics, Inc. | Fixed dose combinations and formulations comprising ETC1002 and ezetimibe and methods of treating or reducing the risk of cardiovascular disease |
| US11116739B2 (en) | 2015-03-16 | 2021-09-14 | Esperion Therapeutics, Inc. | Fixed dose combinations and formulations comprising ETC1002 and one or more statins and methods of treating or reducing cardiovascular disease |
| US11613511B2 (en) | 2019-06-21 | 2023-03-28 | Esperion Therapeutics, Inc. | Methods of making bempedoic acid and compositions of the same |
| US11407705B2 (en) | 2019-06-21 | 2022-08-09 | Esperion Therapeutics, Inc. | Methods of making bempedoic acid and compositions of the same |
| US11760714B2 (en) | 2019-06-21 | 2023-09-19 | Esperion Therapeutics, Inc. | Methods of making bempedoic acid and compositions of the same |
| US11926584B2 (en) | 2019-06-21 | 2024-03-12 | Esperion Therapeutics, Inc. | Methods of making bempedoic acid and compositions of the same |
| US11987548B2 (en) | 2019-06-21 | 2024-05-21 | Esperion Therapeutics, Inc. | Methods of making bempedoic acid and compositions of the same |
| US12344578B2 (en) | 2019-06-21 | 2025-07-01 | Esperion Therapeutics, Inc. | Salt forms of bempedoic acid and methods for using the same |
| US12398087B2 (en) | 2019-06-21 | 2025-08-26 | Esperion Therapeutics, Inc. | Methods of making bempedoic acid and compositions of the same |
| US12404227B2 (en) | 2019-06-21 | 2025-09-02 | Esperion Therapeutics, Inc. | Methods of making bempedoic acid and compositions of the same |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |